Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
10 Cards in this Set
- Front
- Back
|
Pigmented lesion usually seen on attached gingiva that usually has a history of long duration.
- May be increased in pregnancy |
Physiologic (racial) Pigmentation (Melanoplakia)
HISTO - Melanin is secreted by the melanocytes and accumulates in the basal cell layer. |
|
|
Smokers Melanosis
- seen in 21% of smokers - appears as brown patch several cm in diameter - Most common area is mandibular anterier gingiva, buccal mucosa, palate, etc. - Amount of pigmentation appears to be related to amount of tobacco consumed - May disappear months to years after cessation of smoking. Not pre-malignant. |
|
|
Oral Melanotic Macule
- Occurs on oral mucosa (vermillion border and gingiva) - Usually < 7mm - 2:1 Female predilection - Do not usually enlarge after diagnosis - Not related to sun exposure. |
|
|
An area of increased melanin pigmentation mainly within the basal cell layer (w/out an increase in the number of melanocytes) That is related to sun exposure.
|
Ephelis (Freckle)
- usually > 5 mm in diameter - usually occurs on lip (85% lower lip) |
|
Present for a long time
|
Pigmented Cellula Nevus (mole)
- Does not blanch (may not be pigmented) - Most frequently on palate (most common intraoral site), gingiva, Buccal mucosa (2nd most common intraoral site) and lips. - Usually less than 6 mm Most common of all human "tumors" but really rare in the oral cavity. |
|
later stage: Nevus cells are no longer within epithelium but are within the underlying connective tissue.
|
Intramucosal nevus (pigmented cellular neveus, mole)
- Most common intraoral nevi |
|
nevus cells are located at the junction of epithelium and CT
|
Junctional nevus
Other variants - Blue nevus (2nd most common oral nevi) usually hard palate - Congenital melanocytic nevus - Halo nevus - Spitz nevus (Benign juvenile melanoma) |
|
|
Smoker melanosis
|
|
|
Malignant Melanoma
- 3rd most common cancer of skin (83% of all deaths due to skin cancer) - Sunlight is an important etiologic factor - Ulceration is common Two phases of growth. - Radial-growth phase: cells spread laterally but stay confined to epithelium - better prognosis. - Vertical growth phase -Malignant cells begin to invade underlying connective tissue. |
|
|
Acral lentiginous melanoma
- most common form in the oral cavity - This palatal melanoma demonstrates numerous atypical melanocytes in the basilar portion of the epithelium with invasion into the superficial lamina propria. |
