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74 Cards in this Set

  • Front
  • Back
what cells myelinate the CNS and PNS
oligo in the centrer
schwann in the peripheral
what are the three classes of neurons
afferent
efferent
inter
these hvae a sensory receptor with ltos of branching and a cell boey and long peripheral process of the axon are in the PNS and only a short central process axon enters the CNS
afferent neuron
this type of neuron transits information to effector cells. its cell body dendrites anda small esegment of the axon are the in the CNS with most of the axon in the pNS
efferent neurons
this type of neuron functions in integration and lies entirely within the CNS
interneurons
this neuron type is 99 percent of all neurons
interneurons
definition. the specialized junction between two neurons where the electrical activity of the presynaptic neuron influences the excitability of the postsynaptic neuron
synapse
account for 90% of the cells in the CNS
glial cells
what are collaterals
axon side guys that may innervagte several tissues
what are the four types of glial cells in the CNS
oligodendrocytes
astrocytes
microglia
ependymal cells
these cells myelinate the CNS
oligos
these cell are specialized macrophage like cells that perform immune functions in the CNS
microglia
these cells line the fluid filled cavities between the brian and sinal cord and regulate the prouction and flow of CSF
ependymal cells
these cells are for biochemical support of the BBB metabolic support for neurons and other cells and regulate ions and neurotrans and scarring following injury
astrocyte
what glial cell is in charge of scarring in teh CNS
astrocyte
what glial cell is in charge of metabolic support for neurons and surroudning cells
astrocytes
electrical potential =
electrical difference
what is resting membrane potential
-70
the membrane potential at which the flux due to the concentration gradient is equal to the flux due to the electrical gradient
equil potential
what is equil potential based on
conc gradient
electrical gradient
which ion is the main factor in membrane potential
K concentration
which ion is close to the rest membrane potential
potassium
why isn't resting membrane potential equal to potassium
leak potassium channels and some Na movement
whqta sets up the conc gradient
atp pum Na/K
in the pump which way do the ions k and na go
k in na out
review: in the pump what happens
na goes out and k goes in to set up the gradient
important for signaling over short distances
graded potentials
important for long distance signaling along nerve and muscle membranes
action potentials
what are three kinds of graded potentials
synaptic
receptor
pacemaker
can the magnitude of graded potentials vary
yes
which type is decremental
graded
definition. the ability to generate action potentials
EXCITABILITY
action potentials are dependent on what kind of channels
voltage gated ion channels
which channels are slow and which are fast
na fast k slow (leaky)
which is positive and whihc is negative feedback
na positive
potassium negative
what is the difference between absolute and relative refractory periods
relative can have another action potential but only if stronger due to hyperpolarization
what is the best case scenario for fastest travel
myelinated big diameter
which can be depolarization or hyperpolarization
graded
which is depolarization ONLY
action
which potential is initiaed be environmental stimulus or spontaneously
graded
what kind of channels does graded rely on
ligand gated
definition specialized junction between two neurons
synapse
what are the two types of synapses
electrical and chemical
what are the most common type of synapses
chemical
what is the main ion for depoliarizatio in a neuron
calcium
what are two ways that the postsynaptic cell may be activated
IONOTropic
metabotropic
are EPSP and IPSP graded
yes
EPSP is a graded ____
depolarization
is IPSP re de hyper
hyper
what are two ways to reach threshold
summation spatial and temporal
spatial or temporal. which must be the same stimulus
temporal
where is the highest density of voltage gated sodium channels
initial segment
what is the major different between neurotrans and neuromod
neuro mod is slow and depends on G proteins
what is long termp potentiaion
how glutamate ruprtures ampa and nmda receptors
when glutamate containing nuerons rupture they rlease a flodo of glutamate that overstimulates ampa and nmda receptors which is called
excitotoxicty
definiton activated by neurotrans and other chemcial messengers released by nearby neurons glia or the axon terminal itself
autoreceptors
what are the six classes of neurotrans
BANAM
biogenic amines
ach
neuropeptides
aa
misc
what are the biogenic amines
catechol
seratonin
histamine
what are the catechols of the biogenic amines
DA NE EPI
what are the aas
excite glutamate
inhibit glycine GABA
what are the catechols derived from
tyrosine
what is serotonin derived from
tryptophan
what are the receptors for NE and EPI
ADRENERGIC
what are the receptors for ach
nicotinic and muscarinic
what enzyme regulates the synaptic levels of ach
acetylcholinesterase
what are the most prevalent neurotrans in the CNS
AMINO ACIDs aka glutamate and GABA
what are the receptors for glutamate
ampa nmda
group of nerons in the PNS
ganglia
group of neurons in the CNS
nuclei
group of many axons
nerve
group of axons traveling together and links the R and L hemispheres of the CNS
commuissure
a tract; goup of axons taveling together in the CNS
pathway
what are the subdivisions of the brain
DCBC
dienceph
cerebrum
cerebellum
brainstem
forms tghe major output with axons reachign other parts of the cortex and CNS
pyramidal cells