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225 Cards in this Set

  • Front
  • Back
What is pectus excavatum?
Funnel breath - incavement of breast bone.
May cause abnormal position of heart
What is voussure?
A bulge of precordium, showing the thorax is too small for the heart
Pulsation of precordium indicates?
CVS disease & cardiomegaly
What is a systolic pull in intercostal space?
Not pathologic, typical young children
What is precordium?
Heart region
What is PMI?
Point of maximum impulse
Where is normal PMI?
1-2 cm medially from midclavicular line in 4th or 5th intercostal space
What may cause the PMI to move to the left?
- Pleuropericardial adhesions
- Right sided pneumothorax
- Cardiomegaly
Typical sign of left ventricular hypertrophy?
- Apical thrust, located medially from midclavicular line
What things may we palpate in precordial region?
- Apical impulse
- Palpable gallop
- Systolic thrust
- Tactile equivalents of sounds and murmurs
- Precordial thrill
When may we se a systolic thrust (lift) of the sternum?
Hypertrophy / dilatation of right ventricle.

Pathology in normosthenic, normal in asthenic
Where may we palpate the tactile equivalent of 2nd heart sound?
Sternal attachment of left 3rd and 4th ribs
When we may palpate 2nd heart sound, it may mean?
Pulmonary hypertension
What may a tactile equivalent of 1st heart sound mean?
Severe mitral stenosis with membranous valve
How does a precordial thrill feel like?
A purring cat
What does a precordial thrill mean?
Organical valvular disease
Stethoscope: Bell listens best? Example?
Lower frequencies - like 3rd & 4th HS
Stethoscope: Membrane listens best? Example?
Higher frequencies - like decrescendo diastolic murmur or aortic insufficiency
On heart auscultation - what order should we seek for problems?
1. HS
2. Additional sounds
3. Murmurs
Where may we listen for aortic valve?
Right 2nd interspace parasternally
Where may we listen for pulmonary valve?
Left 2nd interspace parasternally
Where may we listen for tricuspid valve?
Lower sternum and lower left sternal border
Where may we listen for mitral valve?
Area of apex of heart
Where is the systolic click of the aortic valve best heard?
Over the apex
Where may the opening snap of mitral valve be best heard?
Over the site of pulmonary ausculation - although it originates from bicuspic valve
Timing of 1st heart sound in cardiac cycle?
Onset of systole
Timing of 2nd heart sound in cardiac cycle?
End of systole
The time b/w 1st & 2nd heart sound is called?
Systolic pause
The time b/w 2nd & 1st heart sound is called?
Diastolic pause
How are heart sounds in obese people?
Softer
How are heart sounds in patients with pulmonary emphysema?
Almost inaudible
What is the cause of 1st HS?
Closure of atrioventricular valves.

Due to higher pressure in ventricles upon contraction, the valves are pushed back.
What are the name of atrioventricular valves?
Mitral valve (bicuspic)
Tricuspid valve
The loudness of 1st HS depends on?
- Speed of pressure increase
- Anatomic condition of valves
- Position of the cusps at the time of ventricular systole
How far after beginning of QRS is onset of 1st HS?
50ms
How long on ECG does the 1st HS last?
100ms
Accentuation of 1st HS may mean?
- Mitral stenosis (mitral is heard over tricuspid)
- Exertional tachycardia
- Fever
- Thyrotoxicosis

It is also a bit delayed, the stenotic valve holds against the pressure a bit longer and then bam it closes
Diminished 1st HS may mean?
Valvular changes due to:
- Thickening
- Fibrosis
- Calcification

Rheumatic heart disease
Acute myocardial infarction
Splitting of 1st HS means?
Asynchronous ventricular contraction (septal defects)
Bundle branch block
--> Not important diagnostically
-----> But must distinguish from 4th HS & early systolic click
What does an early systolic click mean?
Usually an ejection sound
What does a late systolic click mean?
Mitral insufficiency - due to prolapse of the mitral valve into atrium during systole
Reason behind 2nd HS?
Closure of the aortic and pulmonary valves due to higher pressures in the outgoing vessels than inside the ventricles
Which component - pulmonary or aortic - is the most prominent?
Aortic, pulmonary lags behind
Which ventricle expels more blood?
Right ventricle - it has better filling due to suction effect of thorax
What is the physiological splitting of 2nd HS?
That the pulmonary component lags a bit behind
Which HS has the higher pitch?
2nd
Longest time difference between the 2 HS?
0.04 s (at hight of inspiration)
Accentuation of pulmonary component may mean?
- Pulmonary hypertension (mitral stenosis)
- Some congenital heart diseases
- Pulmonary embolism
- Left heart failure
Weakening of pulmonary component may mean?
Fibrotic or calcified leaflets of the valve
A fixed splitting of 2nd heart sound is?
A splitting where both components are clearly splitted and it does not change with breathing
Fixed splitting of 2nd heart sound indicates?
Atrial septal defect
Cause of 3rd HS?
Sudden ending of ventricular distention in initial phase of diastole
Pith of 3rd HS? Bell or membrane?
Low - bell
Pathologic 3rd HS found in?
Mitral incompetence
Ventricular septal defect
LEFT VENTRICULAR FAILURE (40+y)
Constrictive pericarditis
What is pulsus alternans?
An alternating strong and weak pulse
What indicates pulsus alternans?
Left ventricular systolic impairment
When may we hear 3rd HS?
Quick after 2nd HS, like: lub dub (dub)
What is the cause of 4th HS?
Distention of the ventricle caused by atrial systole (active filling)
When may we hear 4th HS?
Just before 1st HS
4th HS may indicate?
Myocardial infarction
Longstanding hypertension
Increased mean atrial pressure
What is a gallop?
Usually tachycardia combined with 3rd or 4th HS
Gallop rhythm is typical (but not conclusive) for?
Left ventricular failure
Cause of diastolic opening snap of the mitral valve?
Rheumatic heart disease
What does it mean that a valve is stenotic?
It cannot open properly, so the leaflets vibrate and create a snapping sound
What is the pericardial knock?
1 HS, 2 HS + early 3rd HS
What is the early systolic (ejection) click?
A click due to stenosis of either aortic or pulmonary valve - the valve cannot open properly, and like a rope holding the door suddenly tightens, this is what makes the sound
When does early systolic click appear?
Quick after 1st HS
What is the late systolic click?
Either:
- Pathologic prolapse of mitral valve into left atrium
- Pericarditis
What is the source of a murmur?
When the flow velocity of blood exceed a certain critical limit in a place where heart cavity or vessels are narrowed or have an uneaven surface
High-pitched murmurs are found where?
In areas with high velocity of blood flow - aortic insufficiency where blood regurgitate through a narrow opening
Low-pitched murmurs are found where?
In areas with lower blood velocity - like mitral stenosis
2 types of systolic murmurs?
Ejection murmur
Regurgitation murmur
When does ejection murmur occur?
In stenosis of aortic or pulmonary valves
What is relative stenosis?
Valves are fine, but either blood flow velocity or the amount of blood (thus velocity) are greater - creating the murmur (like wind through a tunnel)
Shape of ejection murmurs on phonocardiography?
Diamond, introduced by an early systolic click
Where is the murmur heard in aortic stenosis?
2nd right interspace parasternally
Transmit --> Jugular and carotids (more to the right)
Where is the murmur heard in pulmonary stenosis?
Left of the sternum and under clavicles
How may we determine that a murmur is functional and not organic valvular?
Functional is not loud (3 or less) and do not spread
Different types of regurgitation murmurs?
- Decrescendo (weakening in systole)
- Crescendo-decrescendo (similar to ejection (diamond))
- Crescendo (Increasing during systole)
What may cause systolic murmurs?
Mitral valve
Tricuspid valve
Ventricular septal defects
PMI of mitral incompetence?
Apex, spreading to axilla, intensify by squatting
Late systolic murmurs are mostly caused by?
Degenerative changes of elastic valvular structures
--> Leading to prolapse of mitral valve
PMI of tricuspid insufficiency?
Lower sternum, no spread
Very loud murmur, means how severe of organic insufficiency?
Not so much. If no murmur at all it is very severe, cause there is almost no resistance in the valve
PMI of ventricular septal defect murmurs?
Left 4th interspace parasternally
Lower sternum
--> VERY LOUD = Not significant
2 types of diastolic murmurs?
1. Inflow related: Coarse
2. Regurgitant: Decrescendo
When does flow-related murmurs develop?
In stenosis or relative stenosis of an AV valve (M / T)
When does tricuspid stenosis most often occur?
In atrial septal defects - 4x more blood goes through
Why does not inflow related diastolic murmur start just after 2nd HS?
Due to isometric relaxation phase. Here ventricular pressure is still higher than atrial
When does inflow related diastolic murmur start?
At opening of AV valves, when pressure in atrium are higher than ventricular
Is murmur more or less audible in calcified leaflets?
Less
What usually accompany the inflow-related diastolic murmurs?
Diastolic opening snap - since the valve´s opening is limited by adhesions, and the sudden tension and vibration of the valve causes the snap

Presystolic crescendo - loudness increase towards end of systole
How is stenosis and relative stenosis different in inflow-related diastolic murmurs?
Relative stenosis there are no opening snap & no presystolic crescendo
In mitral stenosis, how is pitch and thus what end of stetoschope?
Low - bell
What is the murmur of Austin Flint?
Aortic insufficiency --> Regurgitation. A small stream of regurgitant blood hits mitral valve.
How to distinguish between murmur of mitral and tricuspid stenosis?
Need slow, deep breathing - but not easy to distinguish
Mitral stenosis often leads to?
Pulmonary hypertension
Regurgitant decrescendo murmurs occurs in?
Aortic insufficiency
Pulmonary artery insufficiency
When may we hear the regurgitant murmur of aortic insufficiency?
Right after 2nd HS - due to higher pressure in aorta than LV
Where is PMI of aortic insufficiency?
Right and left 2nd intercostal space parasternally
What side of stethoscope is aortic insufficiency best heard?
Diaphragm - high pitch
How can mitral valve dysfunction lead to pulmonary valve insufficiency?
1. Mitral valve dysfunction
2. Leads to pulmonary congestion
3. Increased pulmonary vascular resistance
4. Secondary dilatation of valvular anulus of pulmonary artery
5. Pulmonary valve insufficiency!! :)
What is the diastolic murmur of Graham Steell?
Murmur of pulmonary valve insufficiency secondary to pulmonary hypertension (thus also usually mitral insufficiency)
Where does continuous murmurs originate?
Places where high pressure vasculature communicates with low pressure systems

E.g. Arteries --> systemic veins
Where do we hear continuous murmur in patients with PDA? (Patent ductus arteriosus of Botallo)
Below left clavicle
What type of murmur do we hear over arteriovenous shunts / fistulas?
Continuous murmur
Function of arteriovenous shunts / fistulas?
In relation du hemodialysis
What is bruit de diable = devil´s murmur?
Murmur created by pressure of the stethoscope causing venous compression.
Pericardial friction rub usually originates from?
Pericarditis
What does pericardial friction rub sound like?
Like walking on frozen snow
If there is fluid in pericardial sac - how is the pericardial friction rub changed?
It dissapears
A louder murmur on squatting indicates?
Regurgitant murmur of mitral valve
Why are murmurs heard worse in standing position?
Since arteriolar resistance decrease
And venous return worsens
When can physical exercise be beneficial to hear a murmur?
In mitral valve stenosis
What is the valsava maneuver?
You push internally like trying to have a bowel movement
What does the valsava maneuver help on the heart?
Increase the pressure in chest
-- Tells the blood not to come back to the heart
--- "Decreasing of preload to the heart"
----- So less stretching of heart muscle, and less efficiency of the heart
What does the valsava maneuver help to discover?
Decrease of all murmurs except:
- Murmur of hypertrophic obstructive cardiomyopathy
- Murmur of mitral valve prolapse
What is, according to the book, recognized as hypertension?
Any over 165/90 mmHg

(over 140/90 is not recommended)
What is regarded as hypotension?
Below 100 mmHg
Systolic BP in lower extremities are how much lower/higher than arms?
10-20 mmHg higher - due to help of gravity
How is BP in lower extermities in patients with coarctation of aorta?
Lower than arms
What is pulsus paradoxus?
A significant decrease in systolic BP during inspiration - exceeding 10 mmHg - called pp when over 20
Pulsus paradoxus exceeding 20 mmHg may indicate?
Cardiac failure
Pulmonary emphysema
Constrictive / exudative pericarditis
What is pulsus alternans?
Alternating strong and weak pulse pressure (peak of systolic BP)
What does pulsus alternans indicate?
Chronic left ventricular myocardial dysfunction
What is extrasystolic bigeminy?
Cardiac arrhytmia where the abnormal heart beat occur every other concurrence
What is definition of a pulse?
A volume change of the artery
What is pulse pressure?
Difference between systolic and diastolic BP
Less than 25mmHg in PulsePressure on the arm indicates?
Low cardiac output
High reading of pulse pressure (>50% of systolic BP) can mean?
Decreased HR
Decreased peripheral resistance
Large stroke volume of LV
Decreased elasticity of arterial wall
Shape of carotid pulse curve in aortic insufficiency?
"Celer et altus"
- Sharp upstroke
- High pulse pressure
- Rapid downstroke
What is the Musset´s sign?
The bouncing of patients head in aortic insufficiency
What may be the cause of the Musset´s sign?
The high pulse curve (water-hammer) or corrigan pulse.
How is the carotid pulse curve in valvular aortic stenosis?
- Slow upstroke with a few downers before slow increase (thrills)
- Pulse reaches peak slowly
How is the carotid pulse curve in subvalvular aortic stenosis with hypertrophic obstructive cardiomyopathy?
- Very rapid upstroke
- Short downstroke before a second upstroke
- Called dicrotic pulse
What is hypertrophic obstructive cardiomyopathy?
Thickening of the LV wall without any appearent reason
What is pulsus bisferiens?
Pulse striking twice, like in the obstructive hypertrophic cardiomyopathy
What is the capillary pulse of Quincke?
When pressing lightly on patients fingernail, one see pink (good perfusion) and pale (low perfusion) parts.

If tissue under nail pulsate in rhythm of heartbeat - this is positive sign (what next q)
What does the capillary pulse of Quinke mean?
Low peripheral vascular resistance
High systolic ejection output

- Aortic incompetence
- Thyrotoxicosis
- Severe anemia
MItral stenosis in adults is always from?
Rheumatic origin
Consequence of blood flow due to mitral stenosis?
Inhibits blood flow from left atrium to ventricle
--> Congestion in left atrium
---> Pulmonary veins
----> Pulmonary capillaries
-----> Pulmonary artery (p.hypertension)
------> Transudate of blood plasma to interalveolar septa and alveoli (p. edema)
-------> Impedes breathing ==> Dyspnea
Auscultatory signs of mitral stenosis?
- Opening snap of mitral valve
- Coarse inflow related diastolic murmur
When does acute mitral incompetence develop?
- Rupture of chordae tendinae (idiopathic or due to endocarditis)
- Ischemic damage to papillary muscle
How are lung findings in mitral insufficiency?
Congested: Crackling rales over lung bases, pulmonary edema
Chronic mitral incompetence is caused by usually?
- Chronic dilatation leading to bad attachment of valve to anulus. "Dilated cardiomyopathy"
- Impairment of papillary muscle function (MI)
Consequence of mitral insufficiency?
More blood to ventricle - volume overload. But a lot is ejected back to atrium - which enlarges greatly
Auscultatory signs of mitral insufficiency? PMI & spread?
Regurgitant systolic murmur, PMI at apex, transmit to axilla
What are greatly enlarged LV & LA clinical signs of?
Heart failure
Physical examination findings of combined mitral stenosis & insufficiency?
VALVULAR STENOSIS
- Opening snap
- Inflow related diastolic murmur

INCOMPETENCE
- Apical systolic murmur
Isolated aortic stenosis is usually congenital or acquired?
Congenital
Aortic stenosis cause what in LV?
Hypertrophy - due to more work against the resistance of the narrowed aortic ostium
First symptom of aortic stenosis may be?
Syncope
Angina pectoris
Auscultatory signs of aortic stenosis?
Systolic click over apex
Long ejection murmur - transmission to carotids
What may cause aortic insufficiency?
Rheumatic heart disease
Syphilis (mesaortitis)
Marfan syndrome
Valvular damage of bact. endocarditis
Long standing systemic hypertension
What is mesaortitis?
Inflammation of middle layer of aorta - due to syphilis
Consequences in heart & flow due to aortic insufficiency?
Ejected blood flows back
-> Increase EDV
--> Increase systolic output
Inspective sign of aortic insufficiency?
Musset´s sign
Carotid pulsation
Auscultatory signs of aortic insufficiency?
- Diastolic decrescendo murmur right after 2nd HS
- PMI in 3rd interspace left/right of sternum (rather than valve area)
What is Flint´s coarse diastolic murmur?
In patients with aortic insufficiency - the regurgitating blood hits the mitral valve
Combined aortic stenosis and insufficiency is heard as?
1. Systolic ejection murmur
2. Diastolic decrescendo murmur
Most common cause of tricuspid insufficiency (thus regurgitation)?
Dilation of right ventricle in heart failure - thus the valvular leaftlets fail to adjust
What happens in tricuspid insufficiency?
Blood is ejected back to RV during systole
What happens in atrial septal defect? (ASD)
Blood from LA goes to RA
-> RA gets volume overloaded
--> Over time it becomes dilated
---> Pulmonary component will lag behind aortic component of 2nd HS
---> SPLITTING OF 2nd HS
Typical auscultatory signs of ASD?
Splitting of 2nd HS
What is the Eisenmenger syndrome?
Congenital ventricular septal defect (VSD) causing L-->R shunt
What does the Eisenmenger VSD cause?
More blood in the pulmonary circulation - causing pulmonary hypertension and cyanosis
Inspection signs of Eisenmenger syndrome?
Voussure & systolic thrust
Cyanosis
(Right ventricular hypertrophy)
Auscultatory signs of Eisenmenger syndrome?
None - silent (!!)
Causes of VSD?
1. Congenital (usually)
2. Perforation post MI
What is Roger´s disease?
A hemodynamically uncomplicated VSD with loud systolic murmur
Auscultatory sounds of VSD?
Loud systolic murmur, depending on the size of the hole. The smaller the larger sound
What is patent ductus arteriosus? (PDA)
Incomplete closure of the duct - leading to shunt of blood from aorta --> pulmonary circulation ("L-->R")
Auscultatory signs of PDA? PMI & transmitted? (diagnostics!)
Continuous systolic-diastolig murmur. PMI in 2nd left interspace parasternally. Transmit to under left clavicle
Cause of valvular stenosis of pulmonary artery?
Congenital
Consequences of pulmonary stenosis?
Hypertrophied RV due to more work against more resistance
Inspectious signs of pulmonary stenosis?
Systolic heaving
Presystolic pulsation of neck veins due to forceful contraction of RA
Auscultatory signs of pulmonary stenosis?
Long systolic ejection murmur
PMI over pulmonary valve
Transmitted under both clavicles
Pulmonary comp. lag after aortic comp.
Cause of coarctation of aorta?
Congenital
What is coarctation of aorta? Consequences?
Narrowing of aorta just after left subclavian artery branch. Leading to increased pressure mechanically and also via activation of RAAS (since kidney is hypoperfused)
Palpatory signs of COA?
Poor pulse in lower extermities - femoral pulse delayed after radial.
Auscultatory signs of COA?
Late systolic murmur, PMI between scapulas
Most important diagnostics of COA?
Pressure difference upper and lower extremities
Where is the pain during angina pectoris?
Behind sternum
Where may anginal pain radiate?
To upper extremities (more left) and to the back
How is the pain in angina pectoris described?
Heavy pressure or squeezing
What releaves the anginal pain?
Nitroglycerin spray sublingually
Characters of MI pain?
Same as anginal - but last longer (+20min)
Not releaved by nitroglycerin!
How is pain in dissecting aneurism of aorta?
Similar to MI, but very sudden, sharp, intensive, radiates to back or abdomen. "Like a truck drove you in the chest"
Pain in pericarditis?
Dull precordial pain. Longlasting (days)
Relief in sitting, worse in supine.
Stabbing pain during cough (like pleuritis pain)
Pain in pulmonary embolization?
Not usually painful. If so - discomfort and dyspnea.
Pain of pleuritis character may develop.
Other causes of pain in precordial area?
- Diseases of cervical spine column
- Diseases of mediastinum and pleura
- Hiatal hernias
- Esophagitis
- Diseases of the bony chest walls
What is dyspnea?
Shortness of breath
2 types of dyspnea?
Exertional (during exercise)
Paroxysmal (sudden)
Exertional dyspnea may be early sign of?
MItral stenosis
What is the purpose of the orthopneic position?
Reduce venous return
Allow usage of auxillary respiratory muscles
What is paroxysmal nocturnal dyspnea?
Wakes up suddenly by shortness of breath - usually same hour every night
How is the paroxysmal nocturnal dyspnea usually described?
Feel like choking or that they have to breathe faster
How is pulmonary edema described by patient?
Severe dyspnea, orthopnea, moist, foamy sputum
What is syncope?
Loss of consciousness due to low cerebral blood perfusion
What is "blackout" syncopes?
Syncope due to short bradyarrhythmia or brief cardiac standstill
What is vasocagal syncope?
The most common syncope - caused by:
- Longtime standing in hot poorly ventilated area
- Pain
- Anxiety
- Sight of blood
- Stimulation of carotid sinus (hypersensitive)
What is exertional syncope? Why is it a serious symptom?
Fainting due to exercise - may be severe heart disease
What may causes of exertional syncope be?
Aortic stenosis
Pulmonary artery stenosis
Severe pulmonary hypertension
What is cyanosis?
Bluish hue of skin & mucous membranes
Cause of cyanosis?
When reduced hemoglobin in capillary blood exceeds 50g/L
1. Stagnation cyanosis
2. Oxygen saturation fall below 85%
Why does stagnation of blood cause cyanosis?
1. More oxygen delivery to tissues
2. Hence more amount of reduced Hb in capillaries
What is the mitral facies?
The cyanotic face developing in mitral valvular disease due to blood stagnation due to increased systemic venous pressure
What is acrocyanosis?
Cyanosis of acral parts like earlobes, nose, fingertips
Normal value of oxygen saturation?
96%
How does fall in oxygen saturation below 85% cause cyanosis?
1. Blood contains less oxygen
2. Normal oxygen extraction from tissues
3. Leads to more reduced Hb, basically.
Difference in peripheral and central cyanosis?
Peripheral: Stagnation of blood
Central: Low oxygen saturation
How does heart compensate for low oxygen saturation?
Increased cardiac output
How mange g/l of sulfhemoglobin may cause cyanosis?
5g/L
How many g/l of methemoglobin may cause cyanosis?
15g/L
Can cyanosis occur in patients with anemia?
No, since all Hb is used for oxygen
Can cyanosis occur in patients with polycythemia?
Yes very easily, because there is a lot of Hb´s free and 50g/L limit is easily exceeded
Cause of local edemas?
- DVT
- Venous valve incompetence
Causes of generalized edema?
- Hypoalbuminemia
- Increased capillary permeability
- Increased filtration pressure in capillaries
Another word for generalized edema?
Anasarca
What is hemoptysis?
Coughing up bloody sputum or blood
Causes of hemoptysis?
Diseases of pulmonary parenchyma
- TB
- Lung cancer
- Bronchiectases
- Lung abcess
Pulmonary congestion
- Usually with mitral valve disease
Pulmonary embolism
Pulmonary hypertension
Rusty sputum may mean?
- Change of erythrocytic Hb to hemosiderin in chronic pulmonary congestion
- Pneumococcal pneumonia
Other symptoms to look for other than hemoptysis in pulmonary embolization?
- Dyspnea
- Pleuritic pain
- EKG changes
- Thrombophlebitis
What is hemoptoe?
Massive expectoration of blood
Usualy cause of hemoptoe?
Broncho-pulmonary disease