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95 Cards in this Set
- Front
- Back
undetected error in blood bank specimens can result in?
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administration of an incompatible blood product and possiblity of a fatal transfusion reaction
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list the blood bank label requirements
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check label against ID braclet( it is only good for 72 hrs)
full name hospital ID# or SS# DOB date and time of collection phlebotomist initials witness (must be 2 persons in room during collection) room # and Bed # (optional) |
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most common test performed by blood bank?
Test determines |
type and screen
blood type (ABO) and RH factor (+/-) |
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compatibility during crossmatch
Done on what blood parts? if incompatible what happens? |
sutability to be mixed
plasma or serum (patient) RBCs(donor) can be fatal(because of aggulation and lysis of RBCs |
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aggulation
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clumping
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lysis
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rupturing
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lookback program ( in ref to blood collection)
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requires notification to all blood recipients when a donor for a blood product they have received has turned positive for a transmissible disease
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autologous donation
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process by which a person donates blood for his own use.
several weeks normal..can be 72 hrs |
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FUO
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fever of unknown orgin
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bacteremia
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bacteria in the blood
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septicemia
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microbes or their toxins in the blood
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blood cultures help determine?
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presence and extent of infection..type of organism..antibiotic most susceptible..effectiveness of treatment
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blood cultures typically ordered when a FUO is?
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immed before or after anticipated fever spikes(bacteria most likely to be present)
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blood culture specimen bottles contain?
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media(nutrient broth..encourages growth of microbes)
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blood culture specimen typically collected in sets of two..they are?
which collected first? |
aerobic(with air)
anaerobic(without air) collect anaerobic first with syringe aerobic first with butterfly(because of air in tubing) |
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skin antisepsis for blood culture
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destruction of microorganisms on the skin
10% povidone or 1-2% tincture of iodine or benzalkonium Chloride (special cleaning pads)infants 2 mos and older and PTs idione sensitive chloroprep(dry for 5 min) chlorhexidine gluconate/isopropyl alcohol preparations (one step application effective with a 30 second scrub) |
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PT on antimicrobial therapy
collect blood culture in an? |
(antibotic therapy)
ARD-antimicrobial removal device (or) FAN-fastidious antomicrobial nuturalization bottles |
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ARD blood collection bottles contain
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resin
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FAN blood collection bottles contain
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activated charcoal
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coagulation sodium citrate tubes must be filled until vacumme exhausted. WHY?
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9:1 ratio of blood to anticoagulant a must
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D-Xylose absorption test used to diagnose?
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malabsorption or failure of the small intestine to absorb nutrients
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what is D-Xylose?
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simple sugar
pentrose present in fruit not normal for blood or urine unless foods are eaten that contain it |
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PP-postprandial
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after a meal
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blood collected 2 hrs after a meal rarely are elevated in what?
elevated indicates what? |
glucose
diabetic |
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2-hour PP screens for
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(glucose test 2 hrs after meal)
diabetes and other metabolism problems |
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GTT
diagnosis ? |
(glucose tolerance test)
carbohydrate metabolism problems |
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major carb is blood is?
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glucose(bodys source of energy)
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OGTT
evaluates? |
(oral glucose test)
body's ability to metabolize glucose |
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2 major types of glucose disorders?
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hyperglycemia(diabetes mellitus-glucose increased)
hypoglycemia(decreased) |
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lactose tolerance test used to determine
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Pt lacks enzyme (mucosal lactase) that is necessary to convert the milk sugar lactose into glucose and galactose
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Pt lacks enzyme (mucosal lactase) suffers from
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gastrointestinal distress and diarrhea following ingestion of milk or other lactose containing food
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lactose tolerance test is perfomed in same manner as?
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2-hour GTT
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paternity testing can also be performed by?
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amniocentesis or chorionic villus sampling(projections of vascular tissue, have same genetic makeup as fertilized egg, become fetal portion of placenta)
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TDM
used for? timing |
Therapeutic drug monitoring
testing of drug levels at specific intervals timing is critical |
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for a drug to be benefical the TDM, peak (max) levels must not? and the trough (min) levels must?
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exceed toxic levels
remain within therapeutic range |
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therapeutic phlebotomy involves?
used to treat? |
withdrawl of large quanities of blood(unit, 500mL)
polycythemia(overproduction of RBCs) hemochromatosis(excess iron deposits in tissues) |
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chain of custody
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when forensic specimens collected-special protocol and form
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ETOH ethanol test
skin antispesis? tube used? |
Blood alcohol test
povidone iodine or (BZK)benzalkonium chloride gray top(sodium floride) |
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Drug screening
NIDA(national institute on drug abuse) collection requirements? |
-Prep:
explain test purpose and procedure advise of rights obtain witnessed signed consent form -collections: special area proctor labeled propely (establish chain of custody sealed and placed in a clocked container documentation carefully maintained |
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POCT
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point of care testing
brings laboratory testing to the PT aka..AST-alternate site testing or ancullary or bed side or near-patient |
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BT test
used for? |
Bleeding time
evaluates platelet plug formation in capillaries to detect platelet function disorders and capillary integrity problems also used in diagnosing problems with hemostasis and as a presurgical screening test |
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accuracy of the results depend on technique in what test
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BT
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BT test
procedure |
bleeding time
performed on volar(inner) lateral surface of forearm, using BP cuff to maintainconstant pressure |
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INR
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international normalized ratio
tests on whole blood from a finger stick |
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ACT
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activated clotting time
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HMT
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Heparin management test
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Pt test used to monitor
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warfin(coumadin) therapy
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APTT/PTT used to screen for?
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bleeding disorders prior to surgery
investigate bleeding or clotting disorders detect clotting factor deficiencies monitor low dose heparin therapy |
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ACT test analyzes activity of
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coagulation factors (used to monitor heparin therapy
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HMT test is used for
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testing high dose heparin monitoring needed in cath labs and surgery
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ABGs measured by POCT
what measured? |
pH(potential hydrogen, acid-base balance)
PCO2(partial pressure of carbon dioxide) PO2(partial pressure of oxygen) |
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PCO2 partial pressure of carbon dioxide is a measure of
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pressure exerted by dissolved co2 in blood plasma, proportional to PCO2 in aveoli
(indicator of how well air is exchanged between blood and lungs) increase is hypoventilation decrease is hyperventilation |
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PO2 partial pressure of oxygen is a measure of
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pressure exerted by dissolved O2 in blood plasma
(indicates the ability of the lungs to diffuse O2 through the alveoli into the blood evalutes the effectiveness of oxygen therapy |
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five most common electrolytes measured by POCT
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Sodium(Na+)
potassium (K+) chloride(Cl-) bicarbonate ion(HCO3-) ionized calcium (iCa2-) |
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most plentiful electrolyte in blood
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sodium
plays major role in maintaining osmotic pressure, acid-base balance, and transmitting nerve impulses |
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hyponatremia
hypernatremia |
reduced and elevated levels of sodium
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electrolyte primarily concentrated within cells
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potassium
very little found in bones and blood released into blood when cells are damaged (major role in nerve conduction, muscle function,acid-base balance,osmotic pressure) influences cardiac output by helping to control rate and force of contractions |
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hypokalemia
hyperkalemia |
decreased and increased blood potassium
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electrolytes that exists mainly in extracelluar spaces
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chloride
(sodium chloride or hydrochloric acid) responsible for maintaining celluar integrity influences osmotic pressure, acid-base balance, water balance |
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what must be supplied together to correct hypokalemia
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potassium and chloride
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electrolyte that plays role in transporting carbon dixoide to lungs and regulation of blood pH
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biocarbonate ion
removal of CO2 by lungs results in decrease of H+ ions and increase of pH hypoventilation results in higher CO2 levels and production of more H+ ions can lead to acidosis |
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electrolyte that accounts for approx. 45% of calcium in blood
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Ionized calcium
( rest bound to protiens and other substances) used for muscular contraction, cardiac function, transmission of nerve impulses and blood clotting |
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Cardiac troponin T (TnT) and troponin I (TnI) are?
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protiens specific to heart muscle,.
rise within hours of myocardial damage |
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ALT-analine transferase
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liver enzyme
monitored on lipid lowering meds done during lipid testing |
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BNP
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B-type natriuretic peptide-(1st objective measurment for CHF-congestive heart failure)cardiac hormone produced by heart in response to ventricular volume expansion and pressure overload
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BNP levels help differentiate between?
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COPD and CHF
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most common POCT test
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glucose
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glucose testing used to monitor?
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diabetes mellitus
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glycosylated Hemoglobin is a diagnostic tool for?
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monitoring diabetes therapy
reflect the average blood glucose for preceding 4-6 weeks A1c is type Hgb tested |
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Hct
measure of? |
Hematocrit
aka..PCV-packed cell volume measure of volume of RBCs in blood |
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Hgb levels are used to monitor PTs with
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anemia
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Guaiac
ued to detect |
Occult blood
hidden blood in feces disease in digestive tract (gastric ulcer and colon cancer) test for peroxidase activity of Hbg molecule (diet free of meat and veggies sources ..will lead to false-positive results) |
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HCG
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human chorionic gonadotropin
hormone produced by placenta (appers in both urine and serum -approx 10 days after conception) preganancy test |
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skin tests?
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TB (PPD)tuberculosis (purified protien derivative)
Aspergillus test (test for hypersensitivity to aspergillus-type of mold) Cocci test - tests for infectious fungus disease caused by coccidioides immitis histo test -test for past or present infection by the fungus histoplasma capsulatum |
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TB test
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determines if developed an immune response to Mycobacterium tuberculosis
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Strep test
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throat swab for detection of group A streptococci
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UA
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regents test(paper strip impregnated with reagents that test for presence of bacteria, blood, bilirubin, leukocytes, protein, urobilinogen, pH, specific gravity)
urinalysis consist of a physical and chemical analysis of specimen as well as microscopic analysis if indicated |
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blood cultures ordered when Patient has?
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FUO
Septicemia bacteremia |
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when drawing a blue top tube
clear/discard tube not required for? required for? why clear? |
not necessary for PT or PTT
necessary all other coagulation tests to clear needle of thromblastin contamination picked up as penetration of skin |
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toxicology
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scientific study of toxins(poisons)
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tosicology tests examine?
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blood
hair urine other body substances |
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drug screening
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random screening (without prior notice)
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bed side testing is also called
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POCT-point of care testing
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BT test evaluates?
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platelet plug formation in capillaries
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coagulation monitoring includes tests for?
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Protime(PT) and INR
activated partial thromboplastin time (APTT or PTT) activated clotting time (ACT) Heparin management test (HMT) |
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coumadin is monitored by?
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PT testing
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arterial blood pH test is a measure of ?
indicates what? |
the body's acid balance
PTs metabolic and respiratory status range 7.35-7.45 |
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below normal pH is refered to as
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acidosis
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above normal pH is refered to as
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alkalosis
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PCO2 is a measure of?
indicator of? |
pressure exerted by dissolved co2 in plasma
indicator of how well air exchanged between blood & lungs |
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PO2 is a measure of?
indicator of? |
pressure exerted by dissolved O2 in plasma
indicator of ability of lungs to diffuse O2-alveloi into blood |
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bicarbonate ion plays a role in?
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transporting CO2 to lungs and regulating pH
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measurement of what protiens is a valuable tool in diagnosing (AMI) acute myocardial Infarction?
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Cardiac troponin T (TnT)
troponin (TnI) |
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what is the first objective measure of CHF(congestive heart failure?
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BNP
B-type natriuretic peptide |
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detection of occult blood in stool is done by what test?
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Guaiac
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