Pharmacy And Toxicology,” Chapter 6,

Front 1

The actual title of the “blue bible” of pharmacology is
1. the Physicians’ Desk Reference
2. The United States Pharmacopoeia and
National Formulary (USP-NF)
3. the Pharmacological Basis of Therapeutics
4. Remington’s Pharmaceutical Sciences

Back 1

The
Pharmacological Basis of Therapeutics (Goodman and Gilman) is a textbook of pharmacology, toxicology, and therapeutics. This work is known as the blue bible of pharmacology.

Front 2

The most common factor influencing the amount of drug given to a patient is
1. weight
2. gender
3. age
4. route of administration

Back 2

Age is the most common factor that influences the amount of drug to be given. An infant requires a lower dose than an adult.

Front 3

What would be the proper dose in milliliters of ampicillin for an 8-year old child if the adult dose is 15 ml?
1. 2
2. 6
3. 9
4. 15

Back 3

age over age + 12 X dose
8/20X15=6

Front 4

What is the name of the rule used to determine appropriate dosage of medication based on a child’s weight?
1. Young’s Rule
2. Clark’s Rule
3. Rule of Nines
4. Minimum Rule

Back 4

The rule governing calculation of pediatric doses based on weight is Clark’s Rule.

Front 5

Determine the appropriate dose in milligrams of medication for a child
weighing 30 pounds if the average dose for
an adult dose is 600 mg.
1. 50
2. 100
3. 120
4. 150

Back 5

weight in pounds over 150 X adult dose = childs dose
30/150X600mg=120

Front 6

In computing the amount of drug to be given to an underweight female, what adjustments to the normal dosage would ordinarily be made?
1. Increase the dosage because of her weight and further increase because of her sex
2. Increase of dosage because of her weight but decrease because of her sex
3. Decrease of dosage because of her sex and further decrease because of her weight
4. Decrease of dosage because of her sex but an increase because of her weight

Back 6

Decrease of dosage because of her sex and further decrease because of her weight

Front 7

A drug given repeatedly to a patient often has to be increased in dosage to maintain the desired effect. The need for a larger
dose is probably caused by
1. an acquired tolerance from habitual use
2. an abnormal sensitivity
3. a cumulative effect from habitual use
4. an individual idiosyncrasy

Back 7

Habitual use—Some patients must take medications continuously, causing their bodies to build up tolerance to the drug.

Front 8

The most common method of administering medications is
1. orally
2. parentally
3. topically
4. intravenously

Back 8

ORAL.—Oral administration of medications is the most common method.

Front 9

Which of the following is an example of a drug injected intradermally?
1. Insulin
2. Procaine hydrocloride
3. Purified protein derivative
4. 2 or 3 above

Back 9

Purified protein derivative

Front 10

Which of the following is NOT a way in which drugs are grouped?
1. By chemical characteristics
2. By their brand names
3. By their source
4. By their action on the body

Back 10

By their brand names

Front 11

Which of the following is a characteristic side effect of antihistamines?
1. Nausea
2. Drowsiness
3. Uricaria
4. Tinnitis

Back 11

Antihistamines may cause drowsiness.

Front 12

Agents that inhibit the growth of microorganisms without necessarily killing them are known as
1. germicides
2. fungicides
3. antiseptics
4. astringents

Back 12

Antiseptics suppress the growth of microorganisms.

Front 13

The drug group most often used to treat dyspepsia is
1. emollients
2. astringents
3. antacids
4. adsorbents

Back 13

Antacids are drugs used to counteract hyperacidity in the stomach .An excess of acid can irritate the mucous membranes and is commonly known as indigestion, heartburn, or dyspepsia.

Front 14

Patients sensitive to penicillin may also exhibit sensitivity to cephalosporins.
1. True
2. False

Back 14

Because the cephalosporins are structurally similar to the penicillins, some patients allergic to penicillin may also be allergic to cephalosporin drugs.

Front 15

Milk or milk products may interfere with the absorption of which of the following drugs?
1. Cephalexin (Keflex)
2. Tetracycline hydrochloride
3. Streptomycin sulfate
4. Erthromycin

Back 15

Tetracyclines should not be administered with milk, milk products, antacids or iron preparations; they combine with metal ions to form nonabsorbable compounds.

Front 16

Macrolides are effective against which of the following organisms?
1. Gram-positive cocci
2. Dermatophytes
3. Parasites
4. Gram-negative

Back 16

Macrolide antibiotics constitute a large group of bacteriostatic agents that inhibit protein synthesis. They are effective gainst gram-positive cocci, Neisseria, Hemophilus, and mycobacteria.

Front 17

Supplemental potassium may be required with which of the following categories of
drugs?
1. Anti-inflammatories
2. Antidiahrreals
3. Antipyretics
4. Diuretics

Back 17

However, loss body fluids due to use of diuretics can seriously deplete electrolytes from the system, and care should be taken to monitor and replenish lost sodium and potassium through diet and supplement therapy.

Front 18

The two most important opium alkaloids are morphine and
1. paraldehyde
2. codeine
3. meperidine
4. cocaine

Back 18

Opium alkaloids, e.g., morphine and codeine, have replaced opium in medical use.

Front 19

Water-soluable vitamins are not excreted in the urine and are stored in the body in
moderate amounts.
1. True
2. False

Back 19

Water-soluble vitamins are excreted in the urine and are not stored in the body in appreciable quantities.

Front 20

As used in the Navy, what is the primary purpose of biological agents?
1. Diagnosis
2. Resuscitation
3. Immunization
4. Pest control

Back 20

Biological agents are prepared from living organisms or their products. The chief purpose served by these preparations in the Navy is the immunization of personnel against infectious disease.

Front 21

Which of the following organizations is responsible for the licensing of biological
agents?
1. Secretary of the Navy
2. Public Health Service
3. American Medical Association
4. Secretary of the Treasury

Back 21

Biological agents include serums, viruses, toxins, antitoxins, antigens, and bacterial vaccines. Manufacturers of these products must be licensed by the Secretary of the Treasury. Their products are monitored by the U.S. Public Health Service.

Front 22

With which of the following is the yellow fever vaccine reconstituted?
1. Sterile water, USP
2. Triple distilled water, USP
3. Sterile, 5% dextrose in water, USP
4. Sterile sodium chloride injection, USP

Back 22

Yellow Fever Vaccine.—This vaccine is a dull, light orange, flaky or crust-like desiccated mass that requires rehydration immediateley before use. It must be stored at or below 0C until rehydration is effected with sterile sodium chloride injection USP.

Front 23

Which of the following vaccines should not be administered to individuals who are sensitive to egg products?
1. Smallpox
2. Plague
3. Influenza
4. Anthrax

Back 23

Influenza Virus Vaccine.—The influenza virus vaccine is prepared from the allantoic fluid of incubated fertile hen eggs.

Front 24

A poison that is introduced into the body in one location and affects the body in another
location is displaying what effect?
1. Local
2. Remote
3. Cumulative
4. Inhibiting

Back 24

A remote effect is produced when a poison affects parts of the body that are remote to the site of application or point of introduction.

Front 25

A poison that is introduced into the body in one location and affects the body in another
location is displaying what effect?
1. Local
2. Remote
3. Cumulative
4. Inhibiting

Back 25

?

Front 26

Which of the following is equal to one onehundredth of a liter?
1. Dekaliter
2. Deciliter
3. Centiliter
4. Milliliter

Back 26

Centiliter

Front 27

The basic unit of weight in the apothecary system is the
1. gram
2. grain
3. dram
4. milliliter

Back 27

In this system, the basic unit of weight is the grain (abbreviated “gr”), and the basic unit of volume is the minim (abbreviated “m”).

Front 28

A prescription requires 2 ounces of a substance stocked in liters. How many milliliters are required to fill the prescription?
1. 0.030
2. 0.060
3. 30.0
4. 60.0

Back 28

1 fluid ounce = 29.57 milliliters= 60

Front 29

A compound requires 40 grains of a substance stocked in kilograms. How many grams are required to prepare the compound?
1. 0.62
2. 2.6
3. 4.2
4. 2,400.0

Back 29

1 grain = 0.065 gram or 65 milligrams
2.6

Front 30

You have 360 grams of a compound. If 54 grams of the compound is silver nitrite, what is the percentage of silver nitrite?
1. 12.5
2. 15.0
3. 17.5
4. 20.0

Back 30

X = 54/360 x 100(%) = 15 (%)

Hint 30

To find the percentage strength when the amount of the active ingredient and the total quantity of the mixture are known, divide the weight or volume of the active ingredient by the
total weight or volume of the mixture. Then multiply the resulting answer by 100 to convert the decimal fraction to percent.