Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
8 Cards in this Set
- Front
- Back
|
Define Agonists |
Bind and stimulate physiological regulatory effects of endogenous compounds |
|
|
Define Antagonists |
Bind but do not have regulatory effects and prevent the binding of endogenous compounds. |
|
|
Define Drug Affinity |
The probability that a drug molecule will bind to an available receptor at any given moment in time |
|
|
Define Drug Efficacy |
The ability of an agonist to produce a biological effect |
|
|
Define Drug Potency |
Measure of drug activity expressed in terms of the amount required to produce an effect of given intensity. |
|
|
Define Drug Selectivity |
Drugs ability to preferentially produce a particular effect and is related to the structural specificity of drug binding to receptors |
|
|
Define Tolerance |
A gradual decrease in responsiveness to a drug |
|
|
What are the mechanisms behind Tolerance? |
Change in receptors Loss of receptors Exhaustion of mediators Increased metabolic degradation Physiological adaptation |
