Pharmacology Respiratory Pharmacology

Front 1

How are respiratory drugs usually administrated ?

Back 1

Inhalation

Front 2

What is the alternate route to inhalation?

Back 2

systamatically

Front 3

Name the (8) common drugs

Back 3

a) beta2-Adenoceptic agents
b) anticholinergics
c) leucotrine modifers
d) corticosteriods
e)Monoclonal antibodies
f) mast cell stabilisers
g) decongestants
h) methyxanthine

Front 4

Describe asthma

Back 4

A syndrom in which there is a recurrent attacks or reversible airway obstruction as a result of broncoconstriction and mucus secretions

Front 5

How is asthma charcterised ?

Back 5

Difficulity breathing out,wheezing and cough

Front 6

what are the two phases in asthma?

Back 6

Immediate and delayed phase

Front 7

What is the treatment in the case of a immediate early attack?

Back 7

Inhaling drugs from a pressurised container

Front 8

what is done in the case of an acute severe asthma attack

Back 8

hospitalisation

Front 9

What are the names of the agent used in the treatment of asthma ?and list 3 examples

Back 9

beta2 -Adrenoreceptors (salbuonol,terabulaim,and samertron)

Front 10

How beta2adrenorepteragents work?

Back 10

stimulits beta 2 adrenorecepers reducing broncodilation and act as a physilological antagonist to varrious spasmogenic agents

Front 11

What are the three ways for B2adrenorecepter agents to be administered ?

Back 11

Aerosol-most common or orally or injection

Front 12

What the three side effects of B2adrenorecepter agents?

Back 12

Tremor,nervoustension and tachycardia

Front 13

Name two examples of methylxanthines ?

Back 13

Theophline and aminophyline

Front 14

How do methylxanthines work?

Back 14

Produce broncodiluation by inhibiting phosphodiesterase therefore causing increased level of CAMP

Front 15

name the adverse effects of methylxanthines ?

Back 15

Stimulite the heart and CNS ;Nausua headache ,insomnia and abdominal dyscomfort

Front 16

What is the difference between theophyline and aminophyline

Back 16

Theophyline is sustained release oral for nocturnal asthma

where as aminophylin is an intervenous drug given for acute sever asthma

Front 17

Give two examples of anti-Inflammatory agents

Back 17

GLucocorticoids and chromoglicate

Front 18

How do anti-inflammatory agents work

Back 18

increase airway caliber by reducing inflammatory reactions

Front 19

Why are anti-Inflammatory agents only used in the delayed phase of asthma

Back 19

Because they are innefective in the Immediate phase

Front 20

How do chromoglicates work?

Back 20

The action of chromglicates is unknown

Front 21

What is COPD

Back 21

Chronic obstructive pulmonary disease

Front 22

How is COPD characterised (4)

Back 22

a) Inflammation of the airway
b) Cough
c)progressive breathlessness
d) damage to the alveoli

Front 23

what 2 agents are usually used against COPD cough ?

Back 23

Codine and pholcodine

Front 24

what the two cough medications used in COPD not used in asthma patients ?

Back 24

They are contraindicated in asthma

Front 25

What receptors to anti-histamines act upon ?

Back 25

H, receptors

Front 26

what are antihistamines used for ?

Back 26

Allergic reactions such as hay-fever

Front 27

What is the defference between new and old antihistomines

Back 27

Old hace antimucolorinic action and cross the blood brian barrier and have side effects of drowsiness
new have and atropine type of effect and do not cross the blood brain barrier and therefore do not cause drowsiness