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21 Cards in this Set
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inhibitor of serotonin storage used for atypical depression, narcolepsy, adn obstructive sleep apnea
side effects: cardiac, hypertension, dizziness, insomina, agitation, rhinitis |
Modafinil
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inhibitors of serotonin degradation used for depression
side effects: systemic tyramine toxicity from consumption of foods that contain tyramine (hypertensive crisis), fever due to increased muscle tone, leukopenia, hepatic failure, drug induced lupus, worsening of depression, dizziness, somnolence, orthostatic hypotension, weight gain, increased liver aminotransferase level, orgasm disorder contraindications: concomitant use of sympathomimetics, bupropion, buspirone, guanethidine, MAOI's, methyldopa, L dopa, L tryptophan, L tyrosine, phenylalanine, CNS depressants, narcotics, dextromethorphan, excessive coffee/chocolate intake, foods with high tyramine, liver disease, pheochromocytoma, HF, general anesthesia/anesthesia with vasoconstrictors |
iproniazid, phenelzine, isocarboxazid
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inhibitor of serotonin storage used for depression
side effects: systemic tyramine toxicity from consumption of foods that contain tyramine (hypertensive crisis), fever due to increased muscle tone, leukopenia, hepatic failure, drug induced lupus, worsening of depression, dizziness, somnolence, orthostatic hypotension, weight gain, increased liver aminotransferase level, orgasm disorder ***** LESS TYRAMINE TOXICITY***** contraindications: concomitant use of sympathomimetics, bupropion, buspirone, guanethidine, MAOI's, methyldopa, L dopa, L tryptophan, L tyrosine, phenylalanine, CNS depressants, narcotics, dextromethorphan, excessive coffee/chocolate intake, foods with high tyramine, liver disease, pheochromocytoma, HF, general anesthesia/anesthesia with vasoconstrictors |
moclobemide, befloxatone, brofaromine
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inhibitor of serotonin degradation used for depression
side effects: systemic tyramine toxicity from consumption of foods that contain tyramine (hypertensive crisis), fever due to increased muscle tone, leukopenia, hepatic failure, drug induced lupus, worsening of depression, dizziness, somnolence, orthostatic hypotension, weight gain, increased liver aminotransferase level, orgasm disorder ***** LESS TYRAMINE TOXICITY***** side effects: systemic tyramine toxicity from consumption of foods that contain tyramine (hypertensive crisis), fever due to increased muscle tone, leukopenia, hepatic failure, drug induced lupus, worsening of depression, dizziness, somnolence, orthostatic hypotension, weight gain, increased liver aminotransferase level, orgasm disorder ***** LESS TYRAMINE TOXICITY***** contraindications: concomitant use of sympathomimetics, bupropion, buspirone, guanethidine, MAOI's, methyldopa, L dopa, L tryptophan, L tyrosine, phenylalanine, CNS depressants, narcotics, dextromethorphan, excessive coffee/chocolate intake, foods with high tyramine, liver disease, pheochromocytoma, HF, general anesthesia/anesthesia with vasoconstrictors *****GREATER FREEDOM WITH DIET***** |
Selegiline
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drugs used for depression, pain syndromes, nocturnal enuresis (I), and OCD (c)
side effects: heart block, cardiac arrhythmias, orthostati c hypotension, MI, agranulocytosis, jaundice, seizure, worsening of depression with suicidal thoughts, bloating, constipatino, xerostomia, dizziness, somnolence, blurred vision, urinary retention contraindications: concomitant use of MAOI, cardiac conduction defects, use in patients after an acute MI |
tricyclic antidepressants: amitriptyline, clomipramine, desipramine, doxepine, imipramine, nortriptyline, trimipramine
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drugs used for depression, anxiety, OCD, post traumatic stress disorder, pain syndrome
side effects: serotonin syndrome, may precipitate mania in BPAD, sexual dysfunction, GI distress, vasospasm, sweating, somnolence, anxiety contraindications: concomitant use of MAOI, pimozide, or thioridazine |
SSRI's: citalopram, fluoxetine, fluvoxamine, paroxetine, sertraline
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drugs used for depression, anxiety, panic disorder, pain syndromes (D)
side effects: neuroleptic malignant syndrome, hepatitis, may exacerbate mania/depression in susceptible patients, hypertension, sweating, weight loss, GI distress, blurred vision, nervousness, sexual dysfunction contraindications: concomitant use of MAOI |
venlafaxine and duloxetine
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drug used for depression and smoking cessation
side effects: tachyarrhythmia, hypertension (esp if combined with nicotine patch), may exacerbate mania in susceptible patietns, pruritus, sweating, rash, dyspepsia, constipation, dizziness, tremor, blurred vision, agitation contraindications: seizure, bulimia/anorexia, concomitant MAOI, abrupt discontinuation of alcohol or sedatives |
bupropion
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drug used for depression
side effects: agranulocytosis, seizure, may exacerbate mania/depression in susceptible patients, somnolence, increased appetite, hyperlipidemia, constipation, dizziness contraindication: concomitant use MAOI |
mirtazapine
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drugs used for depression and insomnia (t)
side effects: priapism, orthostatic hypotension, liver failure, seizure, may worsen mania/depression, sweating, weight change, dyspepsia, dizziness, somnolence, blurred vision contraindications: coadministration of MAOI, pimozide, trizolam, carbamazepin |
nefazodone, trazodone
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serotonin receptor agonist used for anxiety
side effects: ischemia/MI, cerebrovascular accitdent, dizziness, confusion, headache, excitement, blurred vision, hostile feeling/behavior, nervousness |
buspirone
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serotonin receptor agonist used for migraine headaches
side effects: coronary artery spasm, hypertensive crisis, ischemia/MI, cerebrovascular accident, seizure, chest pain, flushing, nausea, dizziness contraindications: ergot agent, concomitant MAOI, ichemic cardiac/cerebrovascular/peripheral vascular syndromes, uncontrolled hypertensino |
sumatriptan, rizatriptan, almotriptan, frovatriptan, eletriptan, zomitriptan
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serotonin receptor antagonist used for glaucoma and hypertension
side effects: orthostatic hypotension, Vtach, flushing, rash, fluid retention, dyspepsia, dizziness, sedation |
ketanserin
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serotonin receptor antagonist used for nausea
side effects: cardia arrhythmia, bronchospasm, increased liver enzymes, constipation, diarrhea, fatigue, headache |
ondansetron
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serotonin receptor antagonist used for IBS with constipation predominance
side effects: hyptension syncope, diarrhea, dizziness, headache contraindications: history of bowel obstruction, abdominal adhesions/symptomatic gallbladder disease, moderate to severe hepatic impairment, severe renal impairment, suspected sphincter of Oddi dysfunction |
Tegaserod and Prucalopride
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serotonin receptor antagonist used for IBS with diarrhea predominance
side effects: severe constipation, acute ischemic colitis, abdominal pain, nausea, headache contraindications: pre existing constipation, concurrent use of fluvoxamine, crohn's disese, UC, diverticulitis, severe hepatic impairment, history of hypercoaguable state, history of impaired intestinal circulation, instestinal stricture, ischemic colitis, toxic megacolon |
alosetron
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drug used for bipolar affective disorder
side effects: acute drug intoxication, severe bradyarrhythmia, hypotension, sinus node dysfunction, hyperkalemia, pseudotumor cerebri, increased intracranial pressure and papilledema, seizure, polyuria, nephrogenic DI, hypothyroidism, goiter, ECG and EEG abnormalities, diarrhea, nausea, muscle weakenss, transient visual field scotoma, renal impairment, acne contraindications: severe debilitation, dehydration, sodium depletion, significant cardiovascular disease, significant renal impairment, lactation |
lithium
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drug used for partial and toic clonic seizures, BPAD, and trigeminal neuralgia
side effects: aplstic anemia, agranulocytosis, thrombocytopenia, leukopenia, AV blck, arrhythmias, Steven Johnson syndrome, toxic epidermal necrolysis, hyponatremia, hypocalcemia, SIADH, porphyria, hepatitis, nephrotoxicity, blood pressure lability, rash, confusion, nystagmus, blurred vision contraindications: comcomitant use MAOI, history bone marrow depression |
Carbamazepine
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drug used for partial adn tonic clonic seizures, atypical absence siezures, and BPAD
side effects: Steven Johnson syndrome, toxic epidermal necrolysis, bone marrow suppression, hepatic necrosis, amnesia, angioedema, rash, ataxia, somnolence, burred vision |
lamotrigine
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drug used for tonic clonic seizures, absence siezures, atypical absence seizures, partial seizures
side effects: hepatotoxicity, pancreatitis, thrombocytopenia, hyperammonemia, GI irritation, weight gain, ataxia, sedation, tremor |
valproic acid
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drug used for ADHD adn narcolepsy
side effects: hypertensino, tachyarrhythmia, Gille de la Tourette's syndrome, seizure, psychotic disorder with prolonged use, restlessness, dysphoric mood, rebound fatigue, addiction potential, loss of appetite, irritability, erectile dysfunction contraindicaitons: advanced cardiovascular disease, glaucoma, hyperthyroidism, MAOI therapy, severe hypertension |
amphetamine and methylphenidate
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