Pharmacology Midterm True Or False

Front 1

Drugs that mimic neurotransmitters are called antagonists

Back 1

false

Front 2

Cytochrome P450 is the enzyme system responsible for metabolism of most drugs

Back 2

true

Front 3

Drugs are mainly excreted in the kidney but may also be excreted in the lungs, saliva, and feces

Back 3

true

Front 4

When a drug causes induction of enzymes, this means that the enzymes which normally break down the drug are inhibited

Back 4

false

Front 5

Grapefruit juice causes a buildup of certain drugs because they can no longer be metabolized by Cytochrome 3A4

Back 5

true

Front 6

According to Dr. Chen, a drug with high protein binding and a narrow therapeuric index is not likely to interfere with the distribution of herbal preparations

Back 6

false

Front 7

When 2 drugs act synergistically, their combined effect is equal to the sum of each drug taken alone

Back 7

false

Front 8

Most drugs are absorbed in the small intestine

Back 8

true

Front 9

According to Dr. Chen, antidiabetic drugs and anticoagulant drugs have a high risk of interacting with herbs

Back 9

true

Front 10

Acetylcholine normally controlls the heart, i.e., is dominant

Back 10

true

Front 11

Acetylcholine causes decreased urination

Back 11

false

Front 12

Neuromuscular blocking agents act at nicotinic receptors

Back 12

true

Front 13

Acetylcholine causes increased urination

Back 13

true

Front 14

Side effects of muscarinic antagonists include salivation and lacrimation

Back 14

false

Front 15

Cholinesterase inhibitors cause a buildup of acetylcholine

Back 15

true

Front 16

Acetylcholine causes mydriases (large pupil)

Back 16

false

Front 17

Muscarinic agonists are used for urinary retention

Back 17

true

Front 18

Muscarinic antagonists have been associated with memory problems

Back 18

true

Front 19

Acetylcholine is responsible for bronchodilation

Back 19

false

Front 20

Acetylcholine controls secretions, i.e., is dominant

Back 20

true

Front 21

To combat low blood pressure, norepinephrine is released and acts at Beta 1 receptors to cause an increase in renin

Back 21

true

Front 22

To combat low blood pressure norepinephrine is released and acts at alpha 1 receptors in the heart to cause increased cardiac output

Back 22

false

((beta 1 receptors, not alpha 1))

Front 23

Angiotensin II and aldosterone both cause retention of water and sodium

Back 23

true

Front 24

Calcium channel blockers work in both the heart and vascular smooth muscle

Back 24

true

Front 25

A common side effect of beta blockers is impotence

Back 25

true

Front 26

Alpha 2 agonists cause norepinephrine to be released in the brain

Back 26

false

Front 27

Alpha 2 agonists cause a decrease in the release of norepinephrine in the brain

Back 27

true

Front 28

All diuretics cause water, sodium, and potassium excretion

Back 28

false

Front 29

Beta blockers that are selective for both beta 1 and beta 2 can be used safely by asthmatic patients

Back 29

false

Front 30

Many antiarrhythmics work by blocking electrolyte (e.g., sodium, potassium, calcium) channels

Back 30

true

Front 31

Drugs that relax vascular smooth muscle cause a decrease in total peripheral resistance

Back 31

true

Front 32

Sympathomimetics are used to stimulate alpha 2 receptors to produce mydriasis for eye exams

Back 32

false

Front 33

Digioxin is an inotropic agent meaning that it causes increased force of contraction in the heart

Back 33

true

Front 34

Vitamin K is used for overdose on heparin

Back 34

false

((protamine sulfate))

Front 35

Anticoagulants do not dissolve clots

Back 35

true

Front 36

There is now a genetic test to see whether people are unusually sensitive to the effects of warfarin

Back 36

true

Front 37

Lipitor is a pregnancy category C

Back 37

false

Front 38

Vitorin is a combination of anticholesterol drugs that decreases absorption of cholesterol and also inhibits synthesis of cholesterol

Back 38

true

Front 39

Grapfruit juice decreases the concentration of Lipitor, thereby reducing side effects of Lipitor

Back 39

false

Front 40

Rhabdomyolysis is a toxic effect of statin drugs

Back 40

true

Front 41

Decreased hepatic function tests (LFTs) indicate liver damage

Back 41

false

Front 42

Anticholinergics and beta blockers are both used for asthma

Back 42

false

Front 43

Anticholinergics and beta 2 agonists are both used for asthma

Back 43

true

Front 44

Leukotriene modulators used for asthma work by inhibiting eosinophil migration

Back 44

true

Front 45

Serevent, a drug used for asthma, has been associated with severe, life threatening asthma

Back 45

true

Front 46

Antihistamines used for respiratory allergic disorders block the histamine 2 receptor

Back 46

false

Front 47

Antihistamine side effects such as dry mouth, blurred vision and urinary retention are due to the anticholinergic effects of antihistamines

Back 47

true

Front 48

One of the problems with inhaled corticosteroids for respiratory disorders such as asthma is that patients can get yeast infections if they don't rinse the mouth after using the inhaler

Back 48

true

Front 49

H2 antagonists work by neutralizing stomach acid

Back 49

false

Front 50

Side effects of proton pump inhibitors include headaches and GI problems

Back 50

true

Front 51

H2 antagonists work to reduce the secretion of gastric acid

Back 51

true

Front 52

Side effects of proton pump inhibitors include headaches and GI problems

Back 52

true

Front 53

H2 antagonists have been associated with risk of dementia in elderly Blacks and Whites

Back 53

false

Front 54

Local antidiarrheals are opiates

Back 54

false

((some are))

Front 55

If a person stops losing weight while taking amphetamine-related anorexiants, the dose should be increased

Back 55

false

Front 56

Adverse reactions to anorexiants involve primarily the cardiovascular and central nervous systems

Back 56

true

Front 57

Meridia causes loss of appetite by inhibiting the satiety center of the brain

Back 57

false

Front 58

People taking Xenical for weight loss can avoid unpleasant side effects by consuming a high fat diet

Back 58

false

Front 59

Certain drugs approved for ADHD, diabetes and epilepsy are being prescribed off label for wieght loss

Back 59

true

Front 60

Ritalin is not associated with psychosis

Back 60

false

Front 61

Tolerance occurs to certain abnormal repetitive movements caused by both dextroamphetamine and methylphenidate

Back 61

false

Front 62

People taking modafinal (Provigil) as a productivity boosting drug may experience a rare but dangerous side effect known as Stevens-Johnson syndrome

Back 62

true

Front 63

If drug abusers crush the ADHD drug lisdexamphetamine (Vynase) and add water to it so that they can inject it, they will not experience an amphetamine high

Back 63

true

Front 64

Meridia is contraindicated for bulimia

Back 64

false

Front 65

Ritalin is not approved for use in children under the age of 6

Back 65

true

((not yet anyway))

Front 66

Tylenol use during pregnancy has been associated with patent ductus arteriosis in newborns

Back 66

false

Front 67

Aspirin use during pregnancy has been associated with patent ductus arteriosis in newborns

Back 67

true

Front 68

NSAIDs should not be used late in pregnancy because of the possibility of bleeding and delayed labor

Back 68

true

Front 69

Daily doses of Tylenol and NSAIDs (except for aspirin) have been associated with high blood pressure

Back 69

true

Front 70

Aspirin and other NSAIDs reversibly block thromboxane in platelets, thereby inhibiting blood clotting

Back 70

false

((aspirin irreversibly blocks thromboxane in platelets))

Front 71

The most effective and most expensive drug for rheumatoid arthritis is methotrexate

Back 71

false

Front 72

Colchincine is used for acute attacks of gout

Back 72

true

Front 73

About 5% of Tylenol is metabolized to a toxic intermediate that requires glutamate in order to be further metabolized to a safe compound

Back 73

false

Front 74

About 5% of Tylenol is metabolized to a toxic intermediate that requires glutathione in order to be metabolized further into a safe compound

Back 74

true

Front 75

Chronic alcohol drikers have increased levels of the cytochrome P450 enzyme that is involved in the metabolism of Tylenol

Back 75

true

Front 76

Cyclooxygenase 2 (COX2) is responsible for protecting the GI tract and the kidney

Back 76

false

Front 77

Cyclooxygenase 1 (COX1) is responsible for protecting the GI tract and the kidney

Back 77

true

Front 78

According to a recent study, 5 of the top 6 drugs causing deaths are painkillers

Back 78

true

Front 79

Treatment for tension headaches is either NSAIDs or benzodiazapines

Back 79

true

Front 80

Both migraines and cluster headaches are believed to be caused by vasoconstriction

Back 80

false

((vasoconstriction --> vasodilation --> pain))

Front 81

Magic mushrooms (psilocybin) have been effective in treating migraine headaches

Back 81

false

Front 82

Magic mushrooms (psilocybin) have been effective in treating cluster headaches

Back 82

true

Front 83

Triptans have been used to relieve both tension and migraine headaches

Back 83

false

Front 84

Triptans have been used to relieve both migraine and cluster headaches

Back 84

true

Front 85

Cluster headaches occur predominantly in men

Back 85

true

Front 86

Tricyclic antidepressants are very effective in treating chronic pain, but they are difficult to treat in an overdose

Back 86

true

Front 87

Opiates cause respiratory depression and this is usually the cause of death in an overdose

Back 87

true

Front 88

Tolerance develops to miosis, constipation and the pain relieving effects of opiates

Back 88

false

Front 89

Lyrica is an anticonvulsant that is also used for chronic pain

Back 89

true

Front 90

People taking opiates for chronic pain are addicted to opiates

Back 90

false

Front 91

Botox is being used to treat migraine headaches

Back 91

true