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8 Cards in this Set
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Define CNS transmitters |
Are biogenic or biochemical substance involved in directly or indirectly in signal transduction or transmission. |
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Classify CNS transmitters |
Broadly classified into 3 1. Neurotransmitters 2. Neuromodulators 3. Neurotropic factors |
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Define neurotransmitters |
Are the most active CNS transmitters involved in signal transduction. That can be - fast or slow neurotransmitters |
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About neurotransmitters 1. Define 2. They can be? 3. Secretion and destruction n 4. Eg of fast Vs slow NT 5. Excitatory neurotransmitters 6. Inhibitory neurotransmitters |
Y |
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Eg of fast Vs slow neurotransmitters |
Fast neurotransmitters 1. Acetylcholine 2. Noradrenaline / adrenaline 3. Glutamate 4. GABA 5. Serotonin Slow neurotransmitters 1. Dopamine 2. Glycine 3. Aspartate 4. Histamine |
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About Excitatory neurotransmitters 1. Define 2. Eg 3.
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1. These are those types of neurotransmitters that bring up an action that leads to increase in neuronal activity. 2. Eg Drugs or agents that cause a) Absence of sleep b) increase in wakefulness c) increase in memory d) increase in hallucinations e) drugs that increase alertness
Eg - *lersinergic acid * some mushrooms * Ach, Glutamate, Aspartate
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Define Neuromodulators 1. Define 2. Xhteristis 3. Eg |
1.Are biogenic or biochemical substance, not principally involved in signal transduction or transmission, but have / exhibit addictive response.. In that summation of Neuromodulators could / will bring about signal transduction Or supportive effect to a weak or slow neurotransmitters can bring about signal transduction... 2. They are never FAST. ie are slow acting.. Could be found neuronally and outside the neuron 3. Eg purine * prostaglandins * purine * prostaglandins * endokephalin * enkephalin * endokephalin * enkephalin |
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Neurotropic factors 1. Define 2. Xhteristis 3. Eg |
1. Defined as CNS transmitters, that act as gene remodeling substance, there by helping to replenish the weary or the dying neurons. 2.They are not found neuronally 3. Eg - substance p - platelet derived growth factor ( PDGF) |
