Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
15 Cards in this Set
- Front
- Back
Name five drugs that cause thyroid disorders.
|
Amiodarone (can cause hypo- and hyper-)
Salicylates (doses >2grams/day --> hypo-) Anticonvulsants (lower total T4) Lithium (hypo- and thyrotoxicosis) Interferon-alpha (mostly hypo-) |
|
Should levothyroxine be taken on a full or empty stomach?
|
empty stomach
|
|
What are two important drug interactions with levothyroxine?
|
Warfarin - patients need more warfarin
Digoxin - lower doses required |
|
Are different levothyroxine products interchangable?
|
No.
|
|
What is the dosing for levothyroxine?
|
1.6-1.7 mcg/kg/day (100-125 mcg)
|
|
After initiating therapy with levothyroxine, when should you recheck the patients TSH levels?
|
in 6-8 weeks
|
|
In what increments should you adjust levothyroxine?
|
12.5-25 mcg/day
|
|
What happens if you suppress TSH to below normal?
|
Osteoporosis, cardiac toxicity
|
|
In a pregnant patient, how often should you monitor their FT4 and TSH levels?
|
Monthly during the 1st trimester
|
|
True or False:
In a patient with hypothyroidism, concurrent hyperlipidemia gets worse with thyroid treatment. |
False: hyperlipidemia often normalizes with treatment.
|
|
In a patient who is hyperthyroid, do they need more or less warfarin?
|
Less because the effects are exaggerated.
|
|
In a patient who is hyperthyroid, do they need more or less digoxin?
|
More because higher amounts are required while thyrotoxic.
|
|
What drug is preferred for thyroid storm and in pregnancy?
|
PTU
|
|
What is the preferred drug for hyperthyroidism?
|
Methimazole
|
|
How long do you treat hyperthyroidism?
|
1-2 years
|