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10 Cards in this Set

  • Front
  • Back
What is Cytoxan (cyclophosphamide)?
An antineoplastic (alkylating agent)
How does Cytoxan work?
It interferes with DNA replication
What is Cytoxan used for?
It treats cancer/chemotherapy.
What are some adverse effects of Cytoxan?
N/V
alopecia
bone marrow suppression
GI toxicity
hemorrhagic cystitis
What should you monitor with Cytoxan?
CBC
platelets
Potassium
I&O
renal function
hearing or tinnitus
What are important nursing interventions with Cytoxan?
hydration
prevent hypokalemia
give antiemetic
hospital guidelines
What are appropriate doses for Cytoxan?
IV: 40-50 mg/kg in divided doses
PO: 1-5 mg/kg
What are possible drug interactions?
Aminoglycoside - kidney toxicity
Furosemide - ototoxicity
What is Phenothiazine (prototype - thorazine)
Antipsychotic "Typical"

May be used as an antiemetic
What is it used for?
Psychosis, N/V and intractable hiccoughs