Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
62 Cards in this Set
- Front
- Back
|
Natural penicillin is the safest drug as far as toxicity is concerned, EXCEPT for its ability to
|
evoke seizures in meningitis and epilepsy and cause hypersensitivity reactions
|
|
|
Co-trimoxazole is a combination of
|
sulfametoxazole and trimethoprim
|
|
|
Entero-hepatic cycling is the property of
|
erythromycin
|
|
|
All of the following penicillins are resistant to penicillinase EXCEPT
|
ampicillin
|
|
|
Niclosamide is a drug used in the treatment of
|
flatworm infestation
|
|
|
Kernicterus may be evoked in newborn or premature children treated with sulfonamides because of
|
displacement of bound bilirubin from albumin
|
|
|
Drugs used in the prophylaxis and treatment of malaria include all of the following EXCEPT
|
sulfametoxazole-trimetoprime
|
|
|
A drug of choice in treatment of clindamycin-induced pseudomembranaceus colitis is
|
vancomycin
|
|
|
Clavulanic acid is an important ageant in the treatment of bacterial infections because
|
it inactivates bacterial beta-lactamase
|
|
|
Doxorubicin (a)
|
damages the myocardium
|
|
|
Dapsone (b)
|
used in treatment of leprosy
|
|
|
Bleomycin (c)
|
damages the lungs
|
|
|
Griseofulvin (d)
|
disrupts mitotic spindle
|
|
|
Methotrexate is the anticancer agent acting by
|
interference with folic acid related purine nucleotide synthesis
|
|
|
Emetine is a drug used in treatment of
|
amebiasis
|
|
|
Which of the following agents is used in the treatment of systemic mycosis
|
amphotericin B
|
|
|
Amantadine is a drug used in the treatment of
|
Parkinson
viral respiratory infections |
|
|
Trimethoprim is a drug that
|
inhibits dihydrofolate reductase
|
|
|
Of the following statements about mechlorethamine select one that is INCORRECT
|
it is the most lipophilic agent and excellently penetrates the brain
|
|
|
All of the following statements about 5-Fluorouracil are true EXCEPT
|
it is a purine analogue (it's a pyrimidine analogue)
|
|
|
In case you cannot use penicillins for treatment, you may substitute them with
|
macrolides (erythromycin)
|
|
|
Sulfadiazine (a)
|
inhibits folate production
|
|
|
Cephalothin (b)
|
inhibits cell wall synthesis
|
|
|
Amphotericin (c)
|
binds to ergosterol
|
|
|
Gentamycin (d)
|
binds to the 30S subunit
|
|
|
Anticancer drugs that are useful in the treatment of the following diseases other than neoplasms include all of the following EXCEPT
|
alopecia
|
|
|
Vincristine (a)
|
Hodgkin's disease
|
|
|
Estrogens (b)
|
prostatic carcinoma
|
|
|
Cyclophosphamide (c)
|
Burkitt's lymphoma
|
|
|
Methotrexate (d)
|
Chorioncarcinoma
|
|
|
Metronidazole is an agent useful in the therapy of
|
infections with anaerobic bacteria and Trichomonas vaginalis
|
|
|
Leucovorin is an agent used for
|
rescue in the course of therapy with methotrexate
|
|
|
Fluoroquinolones (norfloxacin, ciprofloxacin) have the following adverse effects
|
CNS problems
cartilage toxicity in children blood discrasias |
|
|
A possible treatment for M. pneumonia will be
|
erythromycin
|
|
|
Adverse reactions of isoniazid include all of the following EXCEPT
|
alopecia
|
|
|
All of the following statements about penicillin G are correct EXCEPT
|
can be given orally
|
|
|
All of the following statements regarding tetracyclins are true EXCEPT
|
they cause peripheral polyneuropathy
|
|
|
Which of the following agents acts by depolarizing the neuromuscular junction
|
pyrantel
succinylcholine |
|
|
The most dangerous antibiotic as far as bone marrow toxicity is concerned is
|
chloramphenicol
|
|
|
Drug of choice for treatment of Legionella is
|
erythromycin
|
|
|
Vancomycin (a)
|
bacterial agent used in the treatment of C. difficile evoked pseudomembranaceous colitis
|
|
|
Azythromycin (b)
|
a macrolide antibiotic with activity also against G(-)-bacteria
|
|
|
Benzathine penicilline (c)
|
has a prolonged action - given once a week
|
|
|
Acyclovir (d)
|
used in hepatic infections, derivative of guanine
|
|
|
All of the following statements about fluocytosine are correct EXCEPT
|
it is an anticancer drug
|
|
|
Vincristine and vinblastine act through
|
disruption of the mitotic spindle
|
|
|
In case of administration of which antibiotic the food accelerates its absorption from the gut?
|
macrolides
|
|
|
Dapsone (a)
|
inhibits folate synthesis
|
|
|
Quinolones (b)
|
damages cartilages and bones in children
|
|
|
Isoniazide (c)
|
inhibits mycolic acid synthesis
|
|
|
Rifampin (d)
|
causes orange discoloration of urine, mucus, saliva, sweat and tears
|
|
|
Which of the following sulfonamides has the longest half-life?
|
sulfamethoxasole
|
|
|
All of the following statements about imipenem are true EXCEPT
|
it is adminsitered in combination with cisplatin
|
|
|
The drug of choice in treatment of early stages of Lyme disease is
|
doxocycline
|
|
|
All of the following statements about acyclovir are true EXCEPT
|
it is activated in infected cells
|
|
|
Antibiotics of choice in pregnant women are
|
penicillins
|
|
|
The best drug to treat mastitis caused by opportunistic Staphylococcus from oral cavity of breastfed infants are
|
amoxycillin+clavulanic acid
|
|
|
Which of the following drugs is a drug of choice in treatment of anaerobic bacterial infections
|
metronidazole+vancomycin
|
|
|
Which of the following adverse reactions of chloramphenicol is specific for infants
|
Grey syndrome (grey baby syndrome)
|
|
|
Which of the drugs used in the treatment of AIDS is a protease inhibitor?
|
saquanir
|
|
|
Which of the following drugs are not used for the treatment of tuberculosis?
|
griseofulvin
|
|
|
Which of the following antibiotics can be administered for only 3-4 days with a full therapeutic action?
|
azithromycin
|
