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45 Cards in this Set
- Front
- Back
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what does the CNS contain
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brain and spinal cord
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What 2 divisions does the Peripheral Nervous System have
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Senosyr and Motor
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What is the sensory divison of the PNS
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afferent to CNS, heat,light, pain and pressure
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What is the motor division of the PNS
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efferent form the brain to skeletal muscle
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What class of drugs are under the Sympathetic
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alpha 1 & 2
Beta 1 & 2 |
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What does the sensory and motor lack outside the CNS
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a synapse
synpase = a functional space |
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What class of drugs do most respiratory drugs fall under
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sympatheic
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What does the parasympatheic system do?
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cholinergic NS- uses neurofibers that synthesize and use ACH drugs that mimic = cholinergic agents
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What parasympathic has 2 effects what are they?
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Muscarinic and Nicotinic
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What is a Muscarnic effect
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stimulate parasympathetic sites*affects are mediated through the vagus nerve* affects mucus & salivary gland discahrge, decrease in HR, causes vasodilation, decrease in BP
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What is a Nictinic effect?
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receptor sites that stimulates both the parasympathetic and sympatheic NS* end result can icrease BP through vasoconstriction* will increase HR
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What does the sympatheitic system do?
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prepares the body for a stressful encounter
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What chemical mediators does the symaptheic system use
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uses norepinphrine and dopamine
** alpha effect, Beta 1,2 effects, Dopaminergic receptors.** |
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What do alpha 1 drugs do
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excitatory
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What do alpha 2 drugs do
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Inhibitory
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What type of effects does a Beta 1 drugs have?
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excitatory effects
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What type of effects does a Beta 2 drugs have?
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inhibitaory effect
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What does a B1 drug do
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receptors increase rate and force cardiac contraction
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What does a Beta 2 drug do
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relaxes bronchial smooth muscle and vascular beds of skeletal muscles
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What is a dopaminergic receptoe and what effect does it have
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Da1 and Da2 and both inhibitory
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what is a parasympathomimetic
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agents that stimulate the terminal nerve sight either directly or indirectly
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what is direct acting
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drug that resmbles ACH
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What is indirect acting
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drugs that inhibit cholinesterase resulting in an increase in ACH
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What does a parasympatholytic do?
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block ACH receptors - anticholinergics, reverse the blocks by increase ACH, have effects at neuro affector jucntion
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What are the 2 types of catecholamines
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COMT _ Catechol-O methyl transferase, MAO- Monoamine oxidase
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what is metabolism
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analobism + catabolism
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What do the alpha receptors do
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stiilmate the intestion- slows down; alpha-excitability
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What do Beta receptors do?
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stimulation is genreally a relax or excitatory inhibitor with exception to the heart---stimulation occurs
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What is excitaory b1 responsible for
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increase rate and force of contraction
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What is inhibitory beta 2 responsilbe for
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relax bronchial smooth muscle and vascular beds of skeletal muscle
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Catecholamine receptor site "heart" plays what effects on Alpha, Beta 1 &2?
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Alpha minimun/ no recprtos
Beta 1- inc. rate & contraction Beta 2 No receptors |
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Catecholamine receptor site "arteries" plays what effects on Alpha, Beta 1 &2?
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Alpha- constricts inc BP
Beta 1 dilates dec BP Beta 2 nothing |
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Catecholamine receptor site "bronical smooth muscle" plays what effects on Alpha, Beta 1 &2?
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Alpha- no receptors
beta 1 no effect beta 2- relaxes |
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Catecholamine receptor site "skeletal muscle" plays what effects on Alpha, Beta 1 &2?
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alpha- no effect
beta 1 no effect beta 2 tremor |
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Catecholamine receptor site "CNS" plays what effects on Alpha, Beta 1 &2?
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Alpha Unsure
Beta 1 Unsure Beta 2 Stimulates |
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Stimulation of a parasympathetic response =_________?
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Constriction
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What does cAMP do?
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relaxes smooth muscle and inhibits mast degranulation
(good) |
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What do cyclic GMP do
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increases and enhances the release of mast cells
(bad) |
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% is always equla to what measurment
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grams
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What is the formula for calaculating with proportions
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orginal dose = desired dose
________________________ Amount Amount |
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What is the equataion for solving percentage - strength Solution Problems
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Amt of solute = Amt of solute
_________________________ Total Amt 100 Parts |
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When calculating a solution strnegthwhat goes on top and bottom out of wight and volume
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weight on top
volume on bottom |
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If solving for % you do what
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_________ x 1/100 & plug in weight & vol from problem and cross multiply
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If solving for mg you do what
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(% of mg dose) x X
___________________ 100 (30ml) |
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If solving for ml you do what
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% x Weight
___________ 100 X |
