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10 Cards in this Set

  • Front
  • Back
Parasympathetic
Subtype: Cholinergic
Cholinergic effects
• THINK WET
• Eye
• Salivary glands stimulated
• Bronchi constriction
• Heart rate slows
• GI tract→poop
• Urinary bladder→pee
• Increased sweating
Cholinergic receptors
• Nicotinic receptors
o In motor nerves and skeletal nerves
• Muscle contraction
• Muscarinic receptors
o In internal organs
• Secretions (WET)
Neostigmine mechanisms
• Cholinergic drug
• Work in 2 ways:
o Mimic action of Ach
• Urecholine, reglan, pilocarpine
o Inhibit Ach destruction
• Anticholinesterase
Cholinergic Drug Prototype
Neostigmine (prostigmine)
Clinical Uses for cholinergic medications
• Bladder atony→relax bladder
• Antidote for sympathetic symptoms
• Glaucoma
• Altzeimers
• GI tract atony→relax sphincter
contraindications for cholinergic medications
• Do NOT use if:
o Urinary or GI tract obstruction
o Asthma
o Peptic ulcer
o CAD
o Pregnancy
adverse effects of cholinergic medications
• Dehydration
• Over-sympathetic
• Neusance
Anti-cholinergic drugs
• PROTOTYPE: atropine
• Block action of Ach
• DRY
Anti-cholinergic effects (good and bad)
• CNS stimulant
o Alert
o confusion
• Dry eyes
• Dry mouth
• CV-heart rate up
• Pulmonary-respirations up
• Dry skin, temp increse
• GI-constipation, bloating
• Urinary-not peeing, retention