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10 Cards in this Set
- Front
- Back
Parasympathetic
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Subtype: Cholinergic
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Cholinergic effects
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• THINK WET
• Eye • Salivary glands stimulated • Bronchi constriction • Heart rate slows • GI tract→poop • Urinary bladder→pee • Increased sweating |
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Cholinergic receptors
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• Nicotinic receptors
o In motor nerves and skeletal nerves • Muscle contraction • Muscarinic receptors o In internal organs • Secretions (WET) |
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Neostigmine mechanisms
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• Cholinergic drug
• Work in 2 ways: o Mimic action of Ach • Urecholine, reglan, pilocarpine o Inhibit Ach destruction • Anticholinesterase |
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Cholinergic Drug Prototype
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Neostigmine (prostigmine)
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Clinical Uses for cholinergic medications
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• Bladder atony→relax bladder
• Antidote for sympathetic symptoms • Glaucoma • Altzeimers • GI tract atony→relax sphincter |
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contraindications for cholinergic medications
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• Do NOT use if:
o Urinary or GI tract obstruction o Asthma o Peptic ulcer o CAD o Pregnancy |
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adverse effects of cholinergic medications
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• Dehydration
• Over-sympathetic • Neusance |
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Anti-cholinergic drugs
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• PROTOTYPE: atropine
• Block action of Ach • DRY |
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Anti-cholinergic effects (good and bad)
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• CNS stimulant
o Alert o confusion • Dry eyes • Dry mouth • CV-heart rate up • Pulmonary-respirations up • Dry skin, temp increse • GI-constipation, bloating • Urinary-not peeing, retention |