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38 Cards in this Set
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- 3rd side (hint)
ACTH agonist and its use
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Cosyntropin
to dx: CAH and adrenal insufficiency- measure cortisol before and after this drug |
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Somatram and Somatropin
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GH agonists w/ direct and indirect actions
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IGF-1 agonist
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Mecaserpin
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use of Mecaserpin
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Laron dwarfism and GH deficiency
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will dopamine like drugs increase or decrease GH secretion? What are they used for
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decrease release of GH just pretty much like Pegvisomant - used to tx acromegaly
they are bromocriptine and cabergolin |
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ADH acts on what receptors
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V1- vasoconstriction
V2 - renal fluid reabsorption-> increase blood volume->increase arterial pressure |
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FSH agonist
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Urofollitropin and Follitropin
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Pevisomant
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GH antagonist tx of acromegaly. Dopamine agonists like cabergoline and bromocriptine can be used in acromegaly.
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tx of acromegaly
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tx of hyperprolactinima
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bromocriptine or cabergolin
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oxytocin antagonist
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Atosibam
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Menotrophin
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both FSH and LH agonist
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LH agonist
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hChorionic Gonadotropin
use in ovulation induction and male infertility |
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Tx of SIADH
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Conivaptan-inhibits vasopressin receptor and used in SIADH.
Also other drugs used Lithium, Demeclocyline |
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treatment of nephrogenic
diabetes insipidus |
Thiazides, Amiloride
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Octreotide
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somatostatin analog, which is 45 times more potent in inhibiting the GH secretion.
Used for acromegaly, refractory diarrhea (carcinoid syndrome and VIPoma), esophageal varices. It is associated with nausea, vomiting, abdominal cramps and gall stones. |
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Corticorelin
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this is CrH analog
indicated for differentiating pituitary and ectopic production of ACTH in patients with ACTH-dependent Cushing's syndrome. |
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GnRH agonist
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Gonadorelin – short acting- to induce ovulation
Leuprolide, Nafarelin, Goserelin – long acting –tx endometriosis |
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GnRH antagonist
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Ganirelix- NO AE, used in tx of precocious puberty, prostate and breast ca and in endometriosis
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Cosyntropin
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synthetic ACTH agonist
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TX of cental diabetes incipidus
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Desmopressin
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drug to tx premature labor
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Atosiban
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bromocriptin and caberolin
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tx of hyperprolactinoma, they are dopamine like drugs
it's also used in tx of acromegaly |
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IGF 1- agonist
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Mecasermin
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Ganirelix
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GnRH antagonist- used in tx of precocious puberty and prostate and breast ca and endometriosis
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what is Ghrelin
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it's a GI hormone that induces release of GH
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used to prevent postpartum hemorrhage
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oxytocin
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GH antagonist
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pegvisomant
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used to tx nocturnal enuresis in kids
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desmopressin
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used to tx von Willenbrand disease
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desmopressin
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GHRH agonist
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sarmorelin
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CrH agonist
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corticorelin
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TrH agonist
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protirelin
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Leuprolide
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GnRH long lasting agonist
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gonadorelin
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GnRH short lasting agonist
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used to tx refractory diarrhea
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octreotide
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complication of this drug is carpal tunnel syndrome
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GH synthetic preparation
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cause wasting syndrome in AIDS pts
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GH synthetic hormone
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causes seizures and hyponitreamia
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nasal oxytosin if used for tx of milk letdown reflex
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