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10 Cards in this Set

  • Front
  • Back
What are the indications of aspirin as an antiplatelet agent?
ACS, stroke, arterial thrombosis
What is the end product blocked by aspirin
Thromboxane A2 (via COX1)
What are the indications of Clopidogrel?
ACS, stroke, stent, thrombosis
What is the mechanism of Clopidogrel
ADP receptor antagonist, reducing GPIIb/IIIa expression
What is a non bleeding side effect of Clopidogrel?
TTP , due to underlying vWF deffiency
What are the 3 direct GPIIb/IIIa inhibitors?
Abciximab
Tirofiban
Epifibtamide

All three drugs are reversible
What is the effect of Dipyramidole and Cilostazol?
PDE-3 inhibition (this keeps cAMP high in the platelets and blocks the expression of GP IIIb/IIIa
What are the indications of a GP IIb/IIIa blocker?
ACS, PCI
What are the indications of Cilostazol?
PVD, Claudication (similar things really)
What are the indications of Dipyramidole?
Arterial thrombosis, Stroke