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31 Cards in this Set
- Front
- Back
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What are the class IA drugs?
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use mnemonic: Queen Proclaims Diso's Pyramide
Quinodine Procainamide Disopyramide |
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what is the action of a class IA drug?
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increases action potential
increases refractory period used in atrial and ventricular arrhythmias |
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Quinodine
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Class IA anti-arrhythmic drug
affinity for open sodium channels may cause thrombocytopneia increases mortality rate |
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Procainamide
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class IA anti-arrhythmic drug
may produce SLE syndrome not 1st choice in treatment can be used during pregnancy |
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Disopyramide
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class IA anti-arrhythmic drug
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Class IB anti-arrhythmic drugs
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use mnemonic: I's Buy Lidy's Mexican Tacos
IB Lidocaine Mexiletine Tocainide decreases Action potential used in acute ventricular arrhythmias can be used during pregnancy |
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side effects of Class IB drugs?
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paraesthesias
tremor nausea slurred speech |
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what is a side effect of class IB anti-arrhythmic drug Tocainide?
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may cause agranulocytosis
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of the class IB anti-arrhythmic drugs which two are used for long term suppression of arrhythmias?
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Mexiletine
Tocainide |
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What are the class IC drugs?
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use mnemonic: I C Fucked People (especially since these drugs are used for severe/life threatening arrhythmias)
IC Flecainide Porpatenone |
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what class of anti-arrhythmic drug is used to treat fetal SVT?
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Class IC drugs
Flecanide Porpatenone |
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Can Class I anti-arrhythmic drugs be used during pregnancy?
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YES
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What type of drug is the Class II anti-arrhythmics?
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Beta-blockers
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what are the approved class II anti-arrhythmic drugs?
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Esmolol
Metprolol Propanolol Carvedilol |
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what type of arrhythmias are class II anti-arrhythmic drugs used to treat?
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supraventricular and ventricular arrhythmias
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which class of drug is the only drug to show a reduction in the mortality rate of patients who have arrhythmias but are asymptomatic?
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Class II Beta blockers
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When are class III anti-arrhythmic drugs used?
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when all other anti-arrhythmics have failed
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what are the class III anti-arrhythmic drugs?
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Potassium Channel blockers
Amidoarone Ibutilide Dufetilide Sotalol Avoid during pregnancy |
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what is the effect seen on the ECG of a class III anti-arrhythmic drug?
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increases the PR interval
prolongs the action potential increases QT interval |
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Amidoarone
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class III anti-arrhythmic drug
increases PR interval potent inhibitor of abnormal automaticity |
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Ibutilide
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increases PR interval
IV administration prolongs cardiac AP used in treatment of atrial flutter or fibrillation |
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Dufetilide
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class III anti-arrhythmic drug
increases PR interval maintains cardioversion of atrial fibrillation/flutter |
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Sotalol
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Class III anti-arrhythmic drug
has class II properties also (b-blocker) increases PR interval prolongs AP chronic suppression of SV/V arrhythmia |
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What are class IV anti-arrhythmic drugs?
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Calcium channel blockers
Diltizem Verapamil |
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what is the mechanism of action of a class IV anti-arrhythmic drug?
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slow AV conduction velocity, prolong AV refractory period
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what type of arrhythmia are class IV anti-arrhythmic drugs used to suppress?
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Prevention of nodular arrhythmia
supraventricular arrhythmia Protects the heart in atrial flutter & fibrillation |
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what is the preferred class IV anti-arrhythmic drug in pregnancy?
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Verapamil
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What drugs are used for treatment of arrhythmias that are not put into a classic anti-arrhythmic drug class?
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Adenosine
Digoxin Magnesium sulfate |
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how is adenosine used to treat arrhythmias?
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rapid IV bolus
terminate acute supraventricular tachycardia |
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what does digoxin do in treating an arrhythmia?
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blocks Na/K pump
increase K efflux positively inotropic negative chronotropic |
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What is magnesium sulfate used for?
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treating arrhythmias induced by drugs
administered via IV |
