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37 Cards in this Set
- Front
- Back
DOC for infections caused by gram + cocci
Used prophylactically (syphillis, rheumatic fever) Not effective against PCNase producing organisms |
PCN G
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DOC for staph infections
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narrow spectrum PCNase resistant PCN's
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Most frequently prescribed abx in US
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Amoxacillin
(broad spectrum PCN) |
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What should abx be given with to help reduce nausea?
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Food
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Can a patient with a PCN allergy be given Augmentin, Unasyn, or Timentin
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NO
These contain PCN |
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What's the most common drug allergy?
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PCN
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Which group of abx should be used first?
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Narrow spectrum (to help reduce resistance)
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When giving Ampicillin and Genomycin at the same time, which should be given first?
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Amp first (weakens the cell wall) allowing gent to enter
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What's the major side effect of cephalo?
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Bleeding
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What's another major side effect of cephalo? (black box warning)
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C. diff infection
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When should vanc be used?
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Rx severe infxns
MRSA Ototoxicity |
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When should vanc be used?
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Rx severe infxns
MRSA Ototoxicity |
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When should vanc be used?
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Severe Infxns
MRSA |
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Whats the most common side effects of vanc?
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Ototoxicity
Thrombophlebitis Redman's syndrome if given too fast |
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DOC for patients with true PCN allergy
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Eryhromycin
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What's contraindicated while taking erythromycin
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Antihistamines
Could cause fatal dysrhythmias |
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What's are the major SE of tetracycline
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Will stain teeth yellow (children)
Burn easily |
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What are the major SE of gent?
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Nephrotoxicity
Ototoxicity |
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Describe the drug regimen for Non-resistant TB treatment
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Induction phase (2 months) - 4 drugs
Continuation phase (4 months) - 2 drugs |
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Describe the drug regiment for resistant TB
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(2 months) - 5 drugs
(1-2 years) 2-3 drugs (compliance is very difficult) |
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What are the major drug interactions of Rifampin (Rifadin) (drug for TB)
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Oral contraceptives
Warfarin Drugs for HIV infxn |
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What are the major side effects of Ethambutol (Myambutol) TB treatment
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Optic neuritis
Allergy Hyperuricemia (leads to gout) |
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DOC for anthrax
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Cipro
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Major SE of cipro
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GI
CNS - sz Candida of mouth and vagina Achilles tendon rupture *C. diff infxn |
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What is Flagyl's main use
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Infections caused by obligate anerobes
H. pylori C. diff infxns |
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What should you NOT do with Flagyl
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Put in the fridge
(loses its potency) |
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Why are systemic antifungals so toxic to the body
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B/c the fungal membrane resembles the mammalian cell membrane
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What's the major side effect of Amphotericin B (Fungizone) -- used to rx fungal infxn
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Nephrotoxicity
Must be given over at least 6 hours |
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What are the major SE of protease inhibitors
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Hyperglycemia/diabetes - known to precipitate diabetes
Reduced bone density Hepatotoxicity |
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Antacids (Aluminum salts, what are the major side efffects and conta?
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SE - constipation, hypercalcemia
Contra - osteomalacia (will pull more Ca out of bones) Will also reduce absorption of warfarin, dig, Cipro Give 2 hours before or after meals |
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(Antacid) Tums
Major SE |
Constipation, hypercalcemia, metabolic alkalosis
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What will MOM cause
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diarrhea
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What's the problem with histamine 2 receptor antagonists used as an antacid
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Many drug interxns b/c in inhibits the P450 system
Tagment (worse) |
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How do prokinetic drugs work
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Help increase motion through the gut
Increase gastric emptying time |
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What's the contra to prokinetic drugs
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Epilepsy (precipitates sz)
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Antisecretory agents (Prostoglandin analog)
What should be avoided |
Antacids
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When should a stimulant laxative NOT be used
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When there is a possibility of mechanical obstruction
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