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10 Cards in this Set
- Front
- Back
(P) OMEPRAZOLE
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PROTON-PUMP INHIBITOR
4: GERD MECH: inhibits H+/K+ ATP-ase pump --> blocks gastric acid production ADVERSES: headA & D * CYP-450 sys ** **longer duration in asians** * no CRUSHING * * 1 hour b4 meals * |
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(P) RANITADINE
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H2 ANT
4: ulcers MECH: inhibits gastric acid secretion ** DOES NOT HIT CYP-450 ** ** must be given 2 hours apart from antacids ** ** GIVE SLOW or you get hypOtn & arrhymias ** |
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(P) ALUMINUM HYDROXIDE (w/Mg hydroxide)
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ANTACIDS
4: GERD MECH: raises pH in stomach & duodenum ADVERSES: D (frm Al), CONST (frm Mg) - can cancel out, but usually diarrhea wins * give 2 hours b4 meals ** |
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(P) METROCLOPRAMIDE
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PROKINETIC (+ motion)
4: diabetic gastroparesis (inadequete gastric squeezing) MECH: + Fxs of ACh --> faster peristalsis/gastric emptying (dopamine ANT --> same Fx) INTRCT'N: levodopa (dopa agonist) * give 30 mins b4 @ meal ** |
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(P) PANCRELIPASE
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DIGESTIVE ENZYMES
4: lack of pancreatic enzymes MECH: has AMYLASE, LIPASE, & PROTEASE |
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(P) ONDANSETRON
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ANTI-EMETICS
4: NAUSEA & VOMITING MECH: 5-HT3 inhibitor - block sserontonin receptors suppresses stim of CTZ & VC (drugs classes that cause emesis: ANESTHESIA, OPIODS, CHEMO-) * given 4 PONV (post-operative nausea & vomiting) as off-label use * * give 30 mins b4 chemo * * not a PREVENTATIVE 4 PONV - must give after they already abrf * |
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(P) SIMETHICONE
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ANTI-FLATULANTS
4: excess gas MECH: de-foaming breaks surface tension of gas bubbles |
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(P) DIPHENOXYLATE HCl
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ANTI-DIARRHEALS
4: diarhhea MECH: Prolongs intestinal transit time * given w/ atropine to fight addiction * |
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(P) MAGNESIUM HYDROXIDE (milk of Mg)
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ANTI-CONSTIPATION
4: Constipation MECH: attracts H2O to intestinal lumen --> peristalsis |
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(P) ALOSETRON
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4:
IBS MECH: blocks 5-HT3 (blocks serotonin type 3 receptors) * follow w/ H2O * |