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9 Cards in this Set

  • Front
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(P) CAPTOPRIL

(皆ll 終nd 中n -pril)
ANTIHYPERTENSIVE --> ANGIOTENSIN-CONVERTING ENZYME INHIBITORS

4:
HTN, CHF, diabetic nephropathy, & 左eft ventricular dysfunction

MECH:
Inhibits the ACE needed to 化hange inactive angiotensin 吾 --> active angiotensin II

CONTRAS:
2nd and 3rd preg trim

ADVERSES:
** nonproductive cough **
Angioedema, rash, neutropenia, & dyspnea

- Monitor BP throughout

- 呉ive 1 hr B4 meals 4 満ull absorption
(P) LOSARTAN


(usually have -artan)
ANTIHYPERTENSIVE --> ANGIOTENSIN II RECEPTIVE BLOCKERS

4:
HTN, diabetic nephropathy (damaged kidneys 乃rom diabetes), 左eft ventricular dysfunction

MECH:
Selectively blocks binding 之f angiotensin II to the angiotensin II receptors (blocks vasoconstrict.)

1st-線ine Tx 4: LVH (左eft ventricular hypertrophy)

ADVERSES:
diarrhea, asthenia, dizziness, and fatigue

INTERACTS W/ GRAPEJUICE

- Monitor creatinine, BUN, hemoglobin, and hematocrit levels.
normal BP is?
prehypertension?
stage 1 hypertension
stage 2 hypertension
Hypertensive crisis
<120 / <80 mmHg
120-139 / 80-89
140-159 / 90-99
>160 / >100
>210 / >120
(P) EPLERENONE


(勿ot covered deeply)
ANTIHYPERTENSIVE --> SELECTIVE ALDOSTERONE BLOCKERS

4:
HTN

MECH:
Binds selectively to mineralocorticoid receptors, blocking aldosterone binding.
(P) LABETALOL
ANTIHYPERTENSIVE --> ALPHA-BETA BLOCKERS

4:
HTN

- crosses 血lood 脳rain narrier

MECH:
Blocking Alpha-1 --> vasodilation & blocking Beta-1 --> (you block the normal response 之f increased HR) to keep HR the 同ame

CONTRAS:
bradycardia
- careful w/ pts w/ asthma

ADVERSES:
orthostatic hypotension

- get baseline HR
(P) CLONIDINE
ANTIHYPERTENSIVE --> CENTRALLY-ACTING A-2 AGONIST

4:
high BP

MECH:
stimulates the alpha-2 receptors 中n medulla oblangatta, inhibiting the SNS

ADVERSES:
sedation

- reduce dosage slowly to prevent REBOUND HTN
(P) PRAZOSIN
TERA-
DOXA-
ANTIHYPERTENSIVE -->
PERIPHERALLY ACTING A-1 BLOCKERS

4:
high BP
benign prostatic hypertrophy (tera- doxa-)

MECH:
block postsynaptic alpha-1 adrenergic receptors, producing vasodilation

- substantial first-剤ose effect
(P) HYDRALAZINE
ANTIHYPERTENSIVE --> DIRECT ACTING VASODILATORS

4:
Adjunct to anti-hypertensives

MECH:
direct smooth 筋uscle relaxation 之f the arterioles.

CONTRAS:
CAD, and mitral valvular disease

ADVERSES:
Arthralgia, dermatoses, fever, splenomegaly, and glomerular nephritis

- 呉ive with food

- 呉ive w/ beta-blocker or clonidine to reduce chance 之f reflux tachycardia
(P) NITROPRUSSIDE
ANTIHYPERTENSIVE --> DRUGS 4 HTNV CRISIS

4:
hypertensive crisis

MECH:
Directly relaxes vascular smooth 筋uscle --> vasodilation

CONTRAS:
Aortic coarctation or arteriovenous shunting.

ADVERSES:
CYANIDE TOXICITY

- NO drug interactions

-works 疾apidly & dramatically - IV or central 線ine