Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
4 Cards in this Set
- Front
- Back
(P) ASPIRIN
|
SALICYLATE
4: mild-moderate pain analgesic, antipyretic, anti-inflammatory, anti-platelet irreversibly inhibits COX (cyclooxegenase) MECH: Fever: inhibits PGE2 synth in hypothalmus inflamm: inhibits prostaglandin anti-platelet: irrev inhibits Thromboxane A2 CONTRAS: Peptic Ulcer Gout renal / heptic impairmnt bleeding dis on anti-coag thrpy ADVERSES: GI probs RENAL IMPAIR GASTRIC ULCERS GI BEED **NOt 4 kids w/ varicella (REYE'S!!), NOT during preg (esp. 3rd trim)** ** give w/ milk / food** **<81 mg UNcoated daily = for +CV effects** |
|
(P) IBUPROFEN
|
NSAID (Non-steroidal anti-inflammatory)
4: arthritis mild - moderate pain 1o dysmenorrhea migraine anti-inflammation, analgesic, anti-pyretic, reversibly inhibits COX (cyclooxygenase) MECH: Inhibits COX & Prostaglandin - absorbed from GI CONTRAS: active GI dis renal / hepatic impair hemetopoetic dysfunc pts on coagulotherapy NSAIDs - BLACK BOX: MI / STROKE ADVERSES: GI probs Hepatic / renal toxicity ** preg cat D (3rd tri)** ** MONITOR elderlies** **give w/ milk / food** |
|
(P) ACETAMINOPHEN
|
PARA-AMINOPHENOL DERIVATIVE
4: mild pain anti-pyretic MECH: Central - inhibits prostaglandin synthesis in CNS CONTRAS: hepatic dis viral hepatitis alcoholism ADVERSES: OD = fatal rash urticaria (hives) HEPATIC / RENAL TOXICITY **drug of choice 4 kids & pregs** **ACETYLCYSTEINE = antidote** **interacts w/ warfarin (coumadin)** |
|
(P) SUMATRIPTAN
|
SEROTONIN SELECTIVE AGONIST
4: acute migraine (1o line) cluster headA MECH: selects: 5-HT1b/1d reecpts in cranial blood vessels & sens nerves of trigemenovasc sys = vasoconstric CONTRAS: coronary artery dis ischemic cardiac dis CbV dis (cerebrovasc) ADVERSES: CNS: flush / dizzy / wknss / VASOSPADM -> ISCHEMIA IN CV & CbV sys dysrrhythmias angina **give @ beg in headA** **doesn't help with other HeadA types** |