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14 Cards in this Set

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  • Back
  • 3rd side (hint)

Q1


Ind of Insulin


مهم فشخخخ

-DM Type 1 w 2


-DM with pregnancy w lactation


-DM with Stress w Emergency


-DM with severe Liver or Renal Disease


-HyperK مهمة فشخخ


واحدة حامل اول حرف من اسمها K راحت الطوارئ و هي متوترة طلع عندها مشاكل في الكلي كمان عشان كلت كبدة

Q2


Temporary Uses of Insulin


سؤال امتحان

اخر 4


واحدة حامل اول حرف من اسمها K و راحت الطوارئ وهي متوترة فا طلع عندها فشل في الكلي بسبب الكبدة

Q3


Adv of diff Types of Insulin prep


مهم فشخ

1)Ultra-Short (Lispro) :


-Rapid Onset


-better control of post prandial Hyperglycemia


-Less Risk of Delayed Hypoglycemia



2)Short (Regular or Crystalline Zn)


-Used IV or IM in Emergencies ex Ketoacidosis


-Rapid Onset



3)Intermediate acting (NPH)


-Mixed with Regular (biophasic)


-Useful in all forms of Diabetes xpt Ketoacidosis



4)Long acting Glargine


-Max eff maintained for 24h ➡️Good Compliance

Q5


Advs of Insulin

-Hypoglycemia اهم واحد


-Weight Gain مهمة فشخ


-HypoK


-Lipohypertrophy or Lipoatrophy


-Insulin Resistance


-Allergy

Q6


How to Manage Hypoglycemia

-sweets


-IV مهمة فشخ glucose or IM glucagon

Q7



SU



Mech w Advs

-Block ATP sensitive Channels > ⬆️Ca influx > ⬆️insulin


-⬇️Glucagon



-Hypoglycemia اهم واحد


-Weight Gain مهم فشخ


-HSN

Q8


2022 مهم فشخخ


Adv of Repaglinide over Glibenclamide

-Very Rapid Onset


-Less Postprandial Hyperglycemia


-Less Delayed Hypoglycemia


-Used in allergy to Sulfa مهم فشخ

Q9


مهم فشخ


Mech of Metformin

-Insulin Sensitizer


-➖gluconeogenesis اهم واحد


-➕ of Glycolysis


-⬇️intestinal Glucose absorption

Q11


Adv of Metformin over SU



3NO



-No Hypoglycemia


-No Weight Gain


-No Drug interactions

Q12


Advs of Metformin w Pioglitazone

-GIT Upset (Most common)


-Lactic acidosis (Msot serious)



-Na w H2O retention ➡️edema➡️HF


-Weight Gain

Q13


# of Metformin

-Liver Failure


-RF


-HF


-Pneumonia

Q16


مهم فشخخخ


GR Pioglitazone is Delayed Onset

Bec it is agonist for PPAR-Gamma

Q20


Mech of Sitagliptin

Inhibits DPP-4 enzyme through :


A) ⬆️Glucose secretion


B) ⬇️Glucagon secretion

Q21


Drug Therapy of DM TYPE 2