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101 Cards in this Set
- Front
- Back
Acetylsalicylic acid (aspirin) |
Non-selective COX inhibitors NSAIDs |
|
Diclofenac |
Voltarin , NSAIDs non selective |
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Ibuprofen |
NSAIDs non selective |
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Indomethacin |
NSAIDs non selective |
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Ketoprofen |
NSAIDs non selective |
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Naproxen |
NSAIDs non selective |
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Mefenamic |
NSAIDs non selective |
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Meloxicam |
NSAIDs selective COX II |
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Celecoxib |
NSAIDs, selective COX II |
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Levodopa |
Dopamine precursor, Parkinson’s |
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Levodopa |
Dopamine precursor, Parkinson’s |
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Bromocriptine |
Parkinson’s, dopamine receptors agonist, fungus derivative |
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Levodopa |
Dopamine precursor, Parkinson’s |
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Bromocriptine |
Parkinson’s, dopamine receptors agonist, fungus derivative |
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Amantadine |
Parkinson’s, NMDA receptor antagonist |
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Ropinirole |
Parkinson’s, dopamine receptors agonist |
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Ropinirole |
Parkinson’s, dopamine receptors agonist |
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Pramipexole |
Parkinson’s, dopamine receptors agonist |
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Ropinirole |
Parkinson’s, dopamine receptors agonist |
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Pramipexole |
Parkinson’s, dopamine receptors agonist |
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Rotigotine |
Parkinson’s, dopamine receptors agonist |
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Selegiline |
Parkinson’s, MAO inhibitors (type B) |
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Rasagiline |
Parkinson’s, MAO inhibitors (type B, irreversible) |
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Entacapone |
Parkinson’s, COMT inhibitors |
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Entacapone |
Parkinson’s, COMT inhibitors |
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Benzotropine |
Parkinson’s , antimascarinic drug |
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Penicillin G |
B lactam , cell wall synthesis inhibitors |
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Penicillin G |
B lactam , cell wall synthesis inhibitors |
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Penicillin V |
B lactam , cell wall synthesis inhibitors |
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Amoxicillin |
B lactam , cell wall synthesis inhibitors |
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Amoxicillin |
B lactam , cell wall synthesis inhibitors |
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Amoxicillin + Clavulanic acid |
Augmentin , B lactam , cell wall synthesis inhibitors |
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Amoxicillin |
B lactam , cell wall synthesis inhibitors |
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Amoxicillin + Clavulanic acid |
Augmentin , B lactam , cell wall synthesis inhibitors |
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Amoxicillin + Sulbactam |
Unasyn , B lactam , cell wall synthesis inhibitors |
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Penicillin + amino glycoside |
Synergistic effect |
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Cefazolin |
1st generation (Cephalosporins) |
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Cefazolin |
1st generation (Cephalosporins) |
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Cephalexin |
1st generation (Cephalosporins) |
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Cefazolin |
1st generation (Cephalosporins) |
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Cephalexin |
1st generation (Cephalosporins) |
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Cephradine |
1st generation (Cephalosporins) |
|
Imipenem, meropenem , Etrapenem |
Carbapenems |
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AztrEonam |
Monobactam , AE=aerobic, n=negative rod |
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AztrEonam |
Monobactam , AE=aerobic, n=negative rod |
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Vancomycin |
Glycopeptides |
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AztrEonam |
Monobactam , AE=aerobic, n=negative rod |
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Vancomycin |
Glycopeptides |
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Bacitracin |
Glycopeptides |
|
Doxycycline, Minocycline |
Tetracycline, 30 subunit |
|
Doxycycline, Minocycline |
Tetracycline, 30 subunit , protein synthesis inhibitors |
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Tigecycline |
Glycylcyclines , 30 subunit , protein synthesis inhibitors |
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Gentamicin , Neomycin , Tobramycin , Amikacin, streptomycin |
Amino glycosides, protein synthesis inhibitors , 30S distortion (prevent 30&50 complex) |
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Azithromycin, Clarithromycin, Erythromycin |
Macrolides , inhibit peptide translocation (50S) protein synthesis inhibitors |
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Telithromycine |
Ketolide , inhibit peptide translocation , protein synthesis inhibitors |
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Fidaxomicin |
Macrocyclic, just for Cl.difficile , act on sigma subunit of RNA polymerase, protein synthesis inhibitors |
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Clindamaycin |
Lincosamides, peptide translocation, protein synthesis inhibitors |
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Linzolid |
Oxazolidinones, bind to 23S (prevent 30&50 complex), protein synthesis inhibitors |
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Quinupristin/Dalfopristin |
Streptogramins ,inhibit peptide elongation (50S), protein synthesis inhibitors |
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Quinupristin/Dalfopristin |
Streptogramins ,inhibit peptide elongation (50S), protein synthesis inhibitors |
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Chloramphenicol |
inhibit peptide elongation (transferase)(50S), protein synthesis inhibitors |
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(Cipro , Dela ,Gemi , Levo , Moxi , O , Nor , Nali) + floxacin |
Fluroquinolones , inhibit DNA (gyrase in gram -ve), (topoisomerase 4 in gram +ve) |
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Mafenide , Silver Sulfadiazine , Sulfasalazine , Sulfadoxine |
Sulfonamides , inhibit folate synthesis, analog of PAPA |
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Mafenide , Silver Sulfadiazine , Sulfasalazine , Sulfadoxine |
Sulfonamides , inhibit folate synthesis, analog of PAPA |
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Trimethoprim |
Folate reduction inhibitors, |
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Cotrimoxazole |
combination of Trimethoprim & Sulfamethoxazole (folate synthesis & folate reductase inhibitors ) |
|
Oseltamivir , Zanamivir |
Neuraminidase inhibitors, anti influenza A & B , |
|
Oseltamivir , Zanamivir |
Neuraminidase inhibitors = prevent release of new virus, anti influenza A & B , |
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Amantadine , Rimantadine |
Anti influenza A , inhibitors of viral uncoating |
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Ribavirin |
1- anti influenza, guanosine analogue = inhibit replication 2- anti HCV with interferon |
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Interferon-a |
Hepatitis B & C |
|
Tenofovir |
Analogue of adenosine 1- anti HBV DNA polymerase 2- anti HIV reverse transcriptase (NRTIs) |
|
Tenofovir |
Analogue of adenosine 1- anti HBV DNA polymerase 2- anti HIV reverse transcriptase (NRTIs) |
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Entecavir |
Guanosine analogue, anti HBV |
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- previr |
Anti HCV DAAs NS3/NS4A protease inhibitors |
|
-buvir |
Anti HCV DAAs NS3/NS4A polymerase inhibitors |
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-asvir |
Anti HCV DAAs NS3/NS4A replication complex inhibitors inhibitors |
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Acyclovir |
Herpes virus : Varicella-Zoster, H.simplex |
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Ganciclovir |
Herpes virus: Cytomegalovirus (CMV) |
|
HAART |
Combination of HIV drug NRTIs + ( NNRTI or {integrase inhibitors or protease + cobicistat} ) |
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Abacavir , Tenofover , Lamivudine, Stavudine , Zidovudine |
NRTIs , anti HIV |
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Abacavir , Tenofover , Lamivudine, Stavudine , Zidovudine |
NRTIs , anti HIV |
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Delavirdine , Efavirenz, Etravirine, Nevirine , Rilpivirine |
NNRTIs , anti HIV , directly binding to the enzyme |
|
Abacavir , Tenofover , Lamivudine, Stavudine , Zidovudine |
NRTIs , anti HIV, compete with nucleoside |
|
- navir |
Anti HIV , protease inhibitors (prevent maturation of the virus) |
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- tegravir |
Anti HIV, integrase inhibitors |
|
Enfuvirtide |
Anti HIV , fusion or entry inhibitors , Bind to gb41 |
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Enfuvirtide |
Anti HIV , fusion or entry inhibitors , Bind to gb41 |
|
Maraviroc |
Anti HIV , entry inhibitors, Block CCR5 co receptor |
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Amphotericin B |
Anti fungal , systemic ,polyenes , bind to ergosterol and form pores |
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Flucytosine |
Anti fungal , systemic , Antimetabolite , inhibit thymidylate synthase (prevent DNA synthesis) |
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Flucanazole , Itraconazole, Voriconazole |
Anti fungal , systemic , azole : trizoles (FIV) , inhibit fungal cytochrome P450 (prevent ergosterol synthesis) |
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Caspofungin , Micafungin , anidulafungin |
Anti fungal , systemic , Echinocandis, inhibit Beta (1,3)-d-glucan (prevent cell wall synthesis ) |
|
Terbinafine , Tolnaftate |
Anti fungal , cutaneous (skin) , Squalene Expoxidase Inhibitors |
|
Griseofuvin |
Anti fungal , cutaneous (skin) , inhibit fungal cell mitosis & nuclear acid synthesis , disrupt microtubules function |
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Nystatin |
Anti fungal , cutaneous (skin) , polyenes , form pores |
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Ketoconazole , Miconazole, Clotrimazole |
Anti fungal , cutaneous (skin) , azole : Imidazole (KMC), inhibit fungal cytochrome P450 (prevent ergosterol synthesis) |
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Ciclopirox |
Anti fungal , cutaneous (skin) , inhibit transport of essential elements |
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Methenamine |
Urinary tract antimicrobials |
|
Methenamine |
Urinary tract antimicrobials |
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Nitrofurantoin |
Urinary tract antimicrobials |