Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
31 Cards in this Set
- Front
- Back
Griseofulvin
|
bind to mitotic spindles of fungi and prevents division
|
|
Amphotericin B
|
bind to sterol on cell membrane
|
|
Clotrimazole - Lotrimin
|
membrane leakage during cell division
|
|
Amox. and Clavulinate - Augmentin
|
A-inhibit bact. pro. cell synthesis
C-beta lactamase inhib. |
|
Amoxicillin
|
bind to penicillin binding protein and inhibit bact. pro synthesis in cell wall
|
|
Cephalexin - Keflex
|
binds to penicillin binding pro and inhibit bact. pro synthesis in cell wall
|
|
Azithromycin - Zithromax
|
inhib. pro synthesis by binding to 50s bact. ribosome
|
|
Tetracycline
|
inhibit bact. pro. synthesis by interfering with 30S ribosome
|
|
Gentamicin
|
bind to 30S and 50S ribosomal subunits and interfere with pro synthesis
|
|
Sulfamethoxazole
|
competitive antagonist of para-aminobenzoic acid (PABA) which is used by bact. to synthesize folic acid
|
|
Sulfamethoxazole with Trimethoprim - Bactrim or Septra
|
trimethoprim interferes with folic acid at sucessive step giving a synergistic effect
|
|
Ciprofloxacin - Cipro
|
inhibit DNA gyrase (uncoils DNA) and influence nucleic acid metabolism
|
|
Erythropoietin
|
gene regulation via growth factor receptor activation in the bone marrow
|
|
Cyclosporine - Sandimmune
|
blocks intracellular T cell signalling causing inhib. production of IL-2 by T-cells
|
|
Etancercept - Enbrel
|
inactivates TNF alpha (tumor necrosis factor)
|
|
Acyclovir - Zovirax
|
nucleoside analog (inhib. viral DNA polymerase)
|
|
Zidovudine - Retrovir
|
thymidine analog (chain termination)
|
|
Immune Globulins
|
interfere with virus penetrating cells
|
|
Interferons
|
? mb one of:
inhib. viral penetration inhib. viral peptide elongation degrade viral mRNA |
|
Chloroquine
|
accumulate in food vacuole of parasite and prevents detox of heme metabolism (toxic)
|
|
Quinine and Quinidine
|
inhibit nucleic acid synthesis in parasites
|
|
Metronidazole
|
cytotoxic effect on pro and DNA via specific enzyme
|
|
Tetrahydrozoline - Visine
|
vasoconstriction
|
|
Azelastine - Optivar
|
blocks H1 receptor sites
|
|
Ketorolac - Acular
|
cyclooxygenase inhibitor
|
|
Tobramycin - Tobrex
|
inhib. bacterial pro. synthesis
|
|
Timolol - Timoptic
|
blocks ocular ep - decreasing aqueous humour
|
|
Mupirocin - Bactroban
|
inhibits bact. pro. synthesis
|
|
Ketoconazole - Nizarol
|
inhibits sterol synthesis
|
|
Tretinoin - Retin A
|
decrease hyperkeratinization, increases epidermal thickness and decreases collagen synthesis
|
|
Isoretinoin - Accutane
|
decreases hyperkeratinization, sebaceous gland, sebus and propionibacterium acne (bact.)
|