Pharm Test 6C - Nsaids And Acetaminophen

Front 1

NSAIDS and acetaminophen action

Back 1

inhibit COX (cyclooxygenase)

Front 2

action of COX

Back 2

converts arachidonic acid into prostaglandins (PAIN, INFLAMMATION)

Front 3

first generation NSAIDS inhibit

Back 3

COX1 and COX2 (unselectively)

Front 4

second generation NSAIDS inhibit

Back 4

COX 2 selectively

Front 5

3 SE of first generation NSAIDS

Back 5

ulcers

renal

bleeding

Front 6

1 SE of 2nd gen NSAIDS

Back 6

renal

Front 7

prototype for first gen NSAID

Back 7

aspirin

Front 8

four benefits of aspirin

Back 8

inflammation

pain

fever

MI/stroke (antiplatelet)

Front 9

three benefits of of COX 2 inhibition

Back 9

inflammation, pain, fever

Front 10

1 benefit of COX 1 inhibition

Back 10

antiplatelet (MI / stroke)

Front 11

_______ generation NSAIDs aka ___________'s inhibition of COX is irreversible

Back 11

1s generation... aka aspirin

Front 12

single dose of aspirin has antiplatelet effect for life of platelet which is ________

Back 12

8 days

Front 13

take aspirin ___________ before other NSAIDS

Back 13

2 hours before

Front 14

ibuprofren is___________

Back 14

1st generation non aspirin NSAID

Front 15

because of renal impairment properties, aspirin not good for those with

Back 15

at risk for CHF (hypovolemia, hypertension, CHF)

Front 16

aspirin and NSAIDs should be avoided in children with influeza due to potential ________ syndrome

Back 16

reyes syndrome

Front 17

treat allergic reactions with

Back 17

epinephrine

Front 18

three differences between aspirin and non aspirin 1st generation NSAIDS

Back 18

non aspirin 1st generation NSAIDS:

reversible antiplatelet

not for MI

can actually cause MI/stroke

Front 19

aspirin ____________ for labor and delivery

Back 19

not good

Front 20

seond gen NSAIDS also known as

Back 20

coxibs

Front 21

coxibs only inhibit COX

Back 21

COX 2

Front 22

main differences between coxib and 1st generation NSAIDS

Back 22

less ulcers

no antiplatelet

Front 23

coxibs and MI/stroke?

Back 23

yes, they also cause it like non aspirion 1s gen NSAIDS

Front 24

name one coxib

Back 24

celebrex

Front 25

acetaminophen ihbitis prostaglandins in _______ only

Back 25

CNS

Front 26

two benefits of acetaminophen

Back 26

fever

pain

Front 27

one risk of acetaminphen

Back 27

liver damage

Front 28

acetaminophen ihibits metabolism of this drug

Back 28

warfarin

Front 29

watch out for this with acetaminphen

Back 29

rash

Front 30

antidote to acetominophen

Back 30

acetylcysteine

Front 31

other routes NSAIDs (topical etc)

Back 31

wnd with -olacs

Front 32

discard asprin that smells like

Back 32

vinegar

Front 33

NSAIDS with least antiplatelet properties

Back 33

-cylates

Front 34

tinnitus

Back 34

ringing in ear

Front 35

celecoxib (2nd gen NSAID) not good for those with this allergy

Back 35

sulfa allergy

Front 36

NSAIDS and aspirin may interact with this primary prevention measure

Back 36

vaccines

Front 37

NSAIDS cause renal issues with these two heart meds

Back 37

ACE and ARBS (prils, sartans)

Front 38

acetaminophen caution with

Back 38

alcohol

Front 39

alcoholics should take no more than _______ mg of acetaminophen per day

Back 39

2000mg

Front 40

Dysmenorrhea means

Back 40

painful menstrual cramps

Front 41

Hematemesis means

Back 41

vomiting blood

Front 42

which NSAID should you avoid after heart bypass surgery?

Back 42

second gen NSAID, celebrex

Front 43

aspirin poisonoing can have what effect on temperature?

Back 43

fever, hyperthermia