Pharm Test 2 Anemia Drugs

Front 1

Ferrous Sulfate/Gluconate/Fumarate

1)MOA
2)CU
3)AE

Back 1

1)Oral, provides iron

2)Iron Deficiency Anemia; Give for 3 months after correct cause of the anemia

3)Black Stools, nausea, cramps

Front 2

Iron Dextran

1)MOA
2)CU
3)AE

Back 2

1)Parenteral, provides iron

2)Iron Deficiency Anemia; give if cant tolerate oral iron, or have extensive chronic anemia

3)Hypersensitvity reaction; Headache, fever, arthralgia

Front 3

Na Ferric Gluconate Complex

1)MOA
2)CU
3)AE

Back 3

1)Parenteral, provides iron

2)Iron Deficiency Anemia; give if cant tolerate oral iron, or have extensive chronic anemia

3)Headache, Fever, Arthralgia

Front 4

Iron Sucrose

1)MOA
2)CU
3)AE

Back 4

1)Parenteral, provides iron

2)Iron Deficiency Anemia; give if cant tolerate oral iron, or have extensive chronic anemia

3)Headache, Fever, Arthralgia

Front 5

Deferoxamine

1)MOA
2)CU
3)What causes acute iron toxicity?
4)What causes chronic iron toxicity?
5)Most efficient way of treating iron toxicity?

Back 5

1)Iron Chelator: binds to absorbed iron and complex excreted in urine and feces

2)Acute and Chronic Iron Toxicity

3)Child Eats Iron Supplements

4)Hemosiderosis, Thal Major, Transfusions

5)Phlebotomy

Front 6

Vitamin B12

1)MOA
2)CU

Back 6

1)Provides B12

2)Treats megaloblastic anemia (d/t B12 defic) (helps with both the anemia and neuro syndrome) (but takes 5 years for B12 stores in body to get used)

Front 7

Folic Acid

1)CU

Back 7

1)Treats megaloblastic anemia (d/t Folic Acid defic)(helps with only Anemia)(have only 6 months of folic acid stores)

Front 8

Erythropoietin

1)MOA
2)CU
3)AE
4)What does it do for athletes?

Back 8

1)inc release of reticulocytes from BM
inc JAK/STAT receptors on RBC progenitors

2)Anemia of Chronic Renal Failure

3)HTN, Thrombotic episodes, Faster head and neck tumor growth

4)Inc RBC conc ->inc O2 delivery (banned by olympics)

Front 9

Darbepoetin

1)MOA

Back 9

1)Long Acting EPO (has 3X half life of EPO, and decreased clearance)

Front 10

Filgrastrim

1)MOA
2)CU
3)AE

Back 10

1)Stimulates neutrophil production/function

2)Inc neutrophils after cancer chemotherapy

3)G-CSF ->bone pain
GM-> Fever
Capillary Damage, Arthralgias

Front 11

Sargramostin

1)MOA
2)CU
3)AE

Back 11

1)Stimulates neutrophil production/function

2)Inc neutrophils after cancer chemotherapy

3)G-CSF ->bone pain
GM-> Fever
Capillary Damage, Arthralgias

Front 12

IL-11

1)MOA
2)CU

Back 12

1)Inc megakaryocyte progenitors -> inc platelets

2)Thrombocytopenia after cancer chemo (thus dec need for platelet transfusions)

Front 13

Hydroxyurea

1)MOA
2)CU
3)AE
4)How long does it take?

Back 13

1)Inc HbF (dilutes HbS)

2)Pain related to Sickle Cell Disease

3)Bone Marrow Suppression,
Cutaneous Vasculitis

4)Several Months