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6 Cards in this Set

  • Front
  • Back
2 categories of antihistamines
1st generation
2nd generation
1st generation antihistamines
Chlorpheniramine
Diphenhydramine
Promethazine
2nd Generation antihistamines
Loratadine
Fexofenadine
Cetirizine
Desloratadine
Mechanism for Antihistamines
H1 receptor antagonists (inhibit mediator release, basophil migration, and eosinophil recruitment)
Uses for antihistamine
Anti-allergy
Side Effects:
Antihistamines
Anti-muscarinic Actions
Sedative Effects
CNS Depression
Paradoxical Excitation in
Children
Topical use leads to allergic
reactions