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11 Cards in this Set
- Front
- Back
What are the Gram (+) and Gram (-) cell walls made out of?
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1. Peptidoglycan only
2. LPS + Peptidoglycan + others(Porins) |
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How do the PCNs act?(2)
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1. Interact with PBPs
2. Inhibit Transpeptidation |
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What are the first generation PCNs?(2)
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1. PCN V
2. PCN G(Syphillis) |
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What are some Generation 2 PCNs?(3)
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1. Methicillin
2. Naficillin 3. Oxacillin |
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How is naficillin metabolized?(2)
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1. Fat soluble so through the bile
2. Can cause seizures |
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What were the Generation 2 PCNs mainly used for?
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1. Staph
2. They were over used and this is why we have MRSA |
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Name 2 Generation 3 PCNs?
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1. Amoxicillin(B. burgdoferi, H. pylori)
2. Ampicillin(Lysteria) |
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What are the Generation 3 PCNs normally combined with?(3)
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1. Suicide inhibitors(Destroy Beta lactamases)
2. Amoxicillin with Sulbactam 3. Ampicillin with Clavulonic acid |
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Name four generation 4 PCNs and their main target?
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1. Carbenicillin
2. Azlocillin 3. Ticarcillin 4. Pipercillin 1. Pseudomonas aeruginosa |
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What are the side effects of Generation 1 PCN?
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1. Jarrisch Herxheimer happens when lots of Spirochetes Die(Chills, fever, malaise, Mayalgia)
2. Type 1 Hypersensitivity |
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What are the Side Effects of generation two PCNs?
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1. Methicillin can cause interstitial nephritis
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