Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
50 Cards in this Set
- Front
- Back
Primary endogenous substrate for Nitric Oxidase Synthase
|
Arginine
|
|
MOA and effect of nitric oxide
|
Stimulates cGMP which leads to vascular smooth muscle relaxation
|
|
Long acting beta 2 agonist used in asthma
|
Salmeterol
|
|
Muscarinic antagonist used in asthma
|
Ipratropium
|
|
MOA action of cromolyn
|
Mast cell stabilizer
|
|
Methylxanthine derivative used as a remedy for intermittent claudication
|
Pentoxifylline
|
|
MOA of corticosteroids
|
inhibit phospholipase A2
|
|
SE of long term (>5 days) corticosteroid therapy and remedy
|
Adrenal suppression and weaning slowly, respectively
|
|
Antimicrobials
|
|
|
MOA of quinolones
|
Inhibit DNA gyrase
|
|
MOA of penicillin
|
Block cell wall synthesis by inhibiting peptidoglycan cross-linkage
|
|
Drug used for MRSA
|
Vancomycin
|
|
Vancomycin MOA
|
Blocks peptidoglycan synthesis
|
|
Type of resistance found with vancomycin
|
Point mutation
|
|
Meningitis prophylaxis in exposed patients
|
Rifampin
|
|
Technique used to diagnose perianal itching, and the drug used to treat it
|
Scotch tape technique and mebendazole
|
|
Two toxicities of aminoglycosides
|
nephro and ototoxicity
|
|
DOC for Legionnaires' disease
|
Erythromycin
|
|
MOA of sulfonamides
|
Inhibit dihydropteroate synthase
|
|
Penicillins active against penicillinase secreting bacteria
|
Methicillin, nafcillin, and dicloxacillin
|
|
Cheap wide spectrum antibiotic DOC for otitis media
|
Amoxicillin
|
|
Class of antibiotics that have 10% cross sensitivity with penicillins
|
Cephalosporins
|
|
PCN active against pseudomonas
|
Carbenicillin, piperacillin and ticarcillin
|
|
Antibiotic causing red-man syndrome, and prevention
|
Vancomycin, infusion at a slow rate and antihistamines
|
|
Drug causes teeth discoloration
|
Tetracycline
|
|
MOA of tetracycline
|
Decreases protein synthesis by inhibiting 30S ribosome
|
|
Drug that causes gray baby syndrome and aplastic anemia
|
Chloramphenicol
|
|
Drug notorious for causing pseudomembranous colitis
|
Clindamycin
|
|
DOC for tx of pseudomembranous colitis
|
Metronidazole
|
|
Treatment of resistant pseudomembranous colitis
|
ORAL vancomycin
|
|
Anemia caused by trimethoprim
|
Megaloblastic anemia
[TMP inhibits dihydrofolate reductase --> defect in folate metabolism --> megaloblastic anemia] |
|
Reason fluoroquinolones are contraindicated in children and pregnancy
|
Cartilage damage
|
|
DOC for giardia, bacterial vaginosis, pseudomembranous colitis, and trichomonas
|
Metronidazole
|
|
Treatment for TB patients (think RIPE)
|
Rifampin, Isoniazid, Pyrazinamide, and Ethambutol
|
|
Metronidazole SE if given with alcohol
|
Disulfiram-like reaction
|
|
Common side effect of Rifampin
|
Red urine discoloration
|
|
MOA of nystatin
|
Bind ergosterol in fungal cell membrane
|
|
Neurotoxicity with isoniazid (INH) prevented by
|
Administration of Vit. B6 (pyridoxine)
|
|
Toxicity of amphotericin
|
Nephrotoxicity
|
|
SE seen only in men with administration of ketoconazole
|
Gynecomastia
|
|
Topical DOC in impetigo
|
Topical mupirocin (Bactroban)
|
|
DOC for influenza A
|
Amantadine
|
|
DOC for RSV
|
Ribavirin
|
|
DOC for CMV retinitis
|
Ganciclovir
|
|
SE for ganciclovir (3)
|
Neutro, leuko and thrombocytopenia
|
|
Anti-viral agents associated with Stephen Johnson syndrome (2)
|
Nevirapine, amprenavir
|
|
HIV antiviral class known to have severe drug interactions by causing inhibition of metabolism
|
Protease inhibitors
|
|
Antivirals that are teratogens
|
ribavirin, efavirenz, and delavirdine
|
|
Antivirals associated with neutropenia (4)
|
Ganciclovir, zidovudine (AZT), saquinavir, and interferon
Sucks that I Got Zero neutrophils |
|
HIV med used to reduce transmission during birth
|
AZT (zidovudine)
|