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11 Cards in this Set
- Front
- Back
Agent that is metabolized to acetaldehyde by alcohol dehydrogenase and microsomal ethanol-oxidizing system (MEOS)
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Ethanol
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Agent with zero-order kinetics
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Ethanol
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Rate limiting step of alcohol metabolism
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Aldehyde dehydrogenase
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System that increases in activity with chronic exposure and may contribute to tolerance
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MEOS
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Agent that metabolize acetaldehyde to acetate
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Aldehyde dehydrogenase
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Agents that inhibit Acetaldehyde
dehydrogenase |
Disulfiram, metronidazole, certain sulfonylureas and cephalosporins
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Agent used in the treatment of alcoholism, if alcohol is consumed concurrently, acetaldehyde builds up and results in nausea, headache, flushing, and hypotension
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Disulfiram
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The most common neurologic abnormality in chronic alcoholics
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Peripheral neuropathy (also excessive alcohol use is associated with HTN, anemia, and MI)
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Agent that is teratogen and causes a fetal syndrome
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Ethanol
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Agent that is the antidote for methanol overdose
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Ethanol
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Drug that inhibits alcohol dehydrogenase and is used in ethylene glycol exposure
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FOMEPIZOLE – used to prevent formation of toxic metabolites from methanol and ethylene glycol ingestion
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