Pharm Exam 3 Sem 2

Front 1

Prednisone is what drug class?

Back 1

Glucocorticoid

Front 2

Mineralocorticoids maintain ______ and _________ balance

Back 2

Fluid and electrolyte

Front 3

Name a mineralocorticoid

Back 3

Fludrocortisone (Florinef)

Front 4

What is the main mineralocorticoid and what does this mean?

Back 4

Aldasterone. Na and fluid retention

Front 5

Contraindications for a _______________ includes systemic fungal infections

Back 5

Corticosteroid

Front 6

Adrenal can take up to __ weeks to suppress and _____ to recover

Back 6

2 weeks, 9-12 months

Front 7

How do you determine lowest possible dose in steroids?

Back 7

Taper until symptoms worsen

Front 8

DOC for adrenocortical insufficiency

Back 8

Hydrocortisone/cortisone

Front 9

DOC for nonendocrine disorders for anti-inflammatory, antiallergic, immunosuppressive effects

Back 9

Prednisone

Front 10

DOC for cerebral edema. Can penetrate BBB well.

Back 10

Dexamethasone

Front 11

Major adverse reaction for corticosteroids

Back 11

Suppression of HPA axis

Front 12

You can abruptly stop corticosteroids as long as tx is under __ days

Back 12

7

Front 13

Corticosteroid dosage must be ___________ during times of stress

Back 13

Increased

Front 14

Nasal corticosteroids can take ___ weeks to work

Back 14

2

Front 15

Must taper corticosteroids if taking for longer than __ weeks

Back 15

2

Front 16

Thyroid hormone can still stay in the blood for __ weeks after starting antithyroid drugs

Back 16

6

Front 17

Levothyroxine take on empty stomach or with meals?

Back 17

EMPTY stomach!

Front 18

Levothyroxine is what percent protein bound?

Back 18

99%

Front 19

Propylthiouracil (PTU) (Thiomide) tx HYPERthyroidism by

Back 19

Inhibiting production of thyroid hormone and conversion of T4 to T3

Front 20

This drug is used for tx during thyroid storm, pre thyroidectomy, and before or after radioactive iodine therapy

Back 20

PTU

Front 21

This med can be given while the pt is waiting for hyperthyroid med to start working

Back 21

Propranolol

Front 22

Levothyroxine May be given IV to tx

Back 22

Myxedema coma

Front 23

Radioactive iodine can cause hypothyroidism, and may take up to __ months to tx hyperthyroidism

Back 23

3

Front 24

Radioactive iodine is usually a one time dose administered in an outpatient setting. If high dose is used, pt may need to be isolated for __ days (half life of the drug)

Back 24

8

Front 25

May take up to __ months for radioactive iodine to take effect

Back 25

6

Front 26

Do not administer thyroid hormones if HR is > _____ due to drug causing increased workload to the heart. USE CAUTIOUSLY IN PTS WITH CV DISEASE!

Back 26

100 bpm

Front 27

PTU usually given every ___ hours

Back 27

Q8H

Front 28

After age ___, bone resorption exceeds formation

Back 28

35

Front 29

Recommended daily dose of cholecalciferol

Back 29

400-1000 IU

Front 30

This drug class works by binding to bone and preventing calcium to leave to the blood

Back 30

Bisphosphonates

Front 31

Where are bisphosphonates metabolized?

Back 31

They’re not lol. They be excreted directly in urine

Front 32

Take bisphosphonates with or without food?

Back 32

Without. They’re poorly absorbed in the GI tract. Take 30 min before meals

Front 33

Routes of calcitonin (3)

Back 33

SQ, Intranasal, IM

Front 34

This med is a version of Parathyroid hormone

Back 34

Forteo

Front 35

This osteoporosis drug can cause cancer

Back 35

Forteo

Front 36

This drug acts by increasing osteoblasts

Back 36

Forteo

Front 37

When do you give calcitonin and why

Back 37

Bedtime, reduces flushing and nausea

Front 38

Other than sitting up for 30 min to prevent acid after giving bisphosphonates, what is something to look out for

Back 38

Jaw pain

Front 39

Average adult pancreas secretes ___-___ units of insulin daily

Back 39

40-60

Front 40

Basal insulin amount is normally __-__ units per hour

Back 40

1-2

Front 41

Symptoms in type 1 diabetics occurs when only ___-___% of beta cells remain

Back 41

10-20%

Front 42

What insulin is used for emergencies since it is the only insulin that can be given IV

Back 42

Regular (Humulin R, Novolin R)

Front 43

Isophane (NPH) is what type of insulin

Back 43

Intermediate (used long term!)

“The cloudy clouds are long term lol”

Front 44

Black box warning for biguanide

Back 44

Lactic acidosis