Pharm Exam 3 - Drugs

Front 1

Divalprox sodium

Back 1

(Depakote)

Anti-epileptic.
-old generation. sedating, blood serum levels, difficult to manage.

Bipolar mood disorder drug.
-Higher TI than lithium, fewer side effects. Less effective for suicide/relapses

Front 2

Phenytoin

Back 2

(Dilantin)

Anti-epileptic
-old generation, sedating, blood serum levels, difficult to manage.
-S/A Dilantin faces (moon face, round face), acne, hirsutism, gingeval hyperplasia. bad mix with alcohol
naseau/vomiting, nystagmus, ataxia, coarsening of features, hepatic failure, lymphadenopathy, osteomalacia

Front 3

Ethosuximide

Back 3

(Zarontin)

Anti-epileptic
-S/A GI upset, sedation and headaches, potential idiosyncratic reactions (ie: rash, blood dyscrasias) are rare

Front 4

Gabapentin

Back 4

(Neurontin)

Anti-epileptic

New line drug, better tolerated, good seizure control, less sedating

drowsiness, ataxia, weight gain and behavioral changes

Front 5

Levetiracetam

Back 5

(Keppra)

Anti-epileptic

New line drug, better tolerated, good seizure control, less sedating

Somnolence, tiredness, dizziness, and upper respiratory infections

Front 6

Carbidopa/levodopa

Back 6

Parkinson Disease

increases dopamine
(carbidopa is decoy, uses up enzymes in periphery, so more levodopa can cross BBB)

S/A:
1. dyskineasias, choreothosis, ticks, big metabolic requirements
2. on-off effect (also from dose just wearing out)
3. naseau effects
4. vivid dreams, hallucinations

to battle Parkinson symptoms of S L U D G E (salivation, lacrimation, urinary stasis, dizziness, diaphoresis, defacation, GI upset, emeses)

Front 7

Benztropine

Back 7

Parkinson disease

Anti-cholinergic. causes SM to relax, to calm extrapyridmal symptoms (acute dyskinesias caused by anti-psychotic drugs)

S/A: possible heat stroke from losing ability to cool down via sweating. not having signs of overheating

Front 8

Donepezil

Back 8

Alzheimer Disease

the cholinesterase inhibitor

makes more ACh available for brain.

S/A: too much ACh in periphery = cog wheel, salivation, tremors, S L U D G E (salivation, lacrimation, urinary stasis, dizziness, diaphoresis, defacation, GI upset, emeses)

Front 9

Lorazepam

Back 9

(Ativan)

Anti-anxiety. Long acting (slower onset, longer duration)

potentiates GABA

withdrawl possible, sedation, physical dependence

S/A: headache, drowsy, dizzy, veritgo, lethargy, fall hazard, hangover effect,/daytime sleepys, elderly CNS depression

Front 10

Alprazolam

Back 10

(Xanax)

(Ativan)

Anti-anxiety. short-acting (faster onset, shorter duration)

MORE ADDICTING THAN ATIVAN!

potentiates GABA

withdrawl possible, sedation, physical dependence

S/A: headache, drowsy, dizzy, veritgo, lethargy, fall hazard, hangover effect,/daytime sleepys, elderly CNS depression

Front 11

Buspirone

Back 11

(Buspar)

Anti-anxiety

non-addicting, well tolerated, minimal sedation, fewer D/D interactions, MAOI (monoamine oxidase inhibitor = treats depression), CNS depressant.

Becoming first line for anxiety

Front 12

Lithium

Back 12

bipolar / mood stabilizer

Front 13

Divalproex sodium

Back 13

Bi-polar / mood stabilizer

Front 14

SSRI

Back 14

Fluoxetine (Prozac)

Front 15

SNRI

Back 15

Duloxetine (Effexor)

Front 16

Trycyclics

Back 16

imipramine (Tofranil)

Front 17

MAOIs

Back 17

isocarboxazid (Marplan)

Front 18

Buprorion

Back 18

(Welbutrin)

anti-depressant

Front 19

Haloperidol

Back 19

(Haldol)

First gen

Anti-psychotic/neuroleptics

Front 20

Clozapine

Back 20

(Clozaril)

Second gen

Anti-psychotic/neuroleptics

Front 21

Quetiapine

Back 21

Anti-psychotic/neuroleptics

Front 22

Digoxin

Back 22

Inotropix agent

for heart failure
increase squeeze, decreases HR

low K+ increases risk of Dig toxicity