Pharm Exam 2 Drugs And Categories

Front 1

Cholinergic Agonists

Back 1

Teens Pile in Bethany's Chevy Car someWhere
Nicotine Pilo Bethan Ceve Carb Vare
Bethanechol
Pilocarpine
Cevimiline
Carbachol
Nicotine
Varemidine (chantix)

Front 2

Cholinesterase Inhibitors

Back 2

EdroNeoPhysoEchoOrgo2-PAM- DONE! (say it fast)
Edropium
Neostigmine
Physostigmine
Organophosphate Pesticides
Echothiophate
Donepazil
2-PAM

Front 3

Cholinergic Antagonists

Back 3

Scopolamine
Tolterodine (Detrol)
Solfenacin (Versican)
Glycopyrolate (Robinul)
Oxybutymin
Dicyclomine (Bentyl0
Ipratroprium (atrovent)
Tropicamide (Mydriacil)
Diphenoxylate-atropine (lomotil)

Front 4

Non Depolarizing Muscle Block

Back 4

D-uronium
D-Tubocurarine
Pancuronium
Vecuronium
Cisatracurim
Rocuronium

Front 5

Depolarizing Muscle Block

Back 5

Succinylcholine

Front 6

Ganglion Blockers

Back 6

Mecamylamine (inversine)
Hexamethonium

Front 7

alpha blocker

Back 7

phentolamine
phenoxybenzamine (dibenzylene)

Front 8

A1 blocker

Back 8

Prazoisn (minipress)
Tamsulosin (flomax)

Front 9

A2 blocker

Back 9

Yohimbine

Front 10

B blocker

Back 10

Propanolol

Front 11

Beta 1 blocker

Back 11

B-Men
Metaprolol (lopressor)
Esmolol (brevibloc)
Betaxolol (betoptic)
Nebivolol (Bystolic)

Front 12

Beta Blocker W/ Intrinsic Sympathetic Activity

Back 12

PinAce (Penis, sympathetic, pfffff)
Pindolol
Acebutolol

Front 13

A,B combo blocker

Back 13

ABs=Core (muscles)
Carvedilol (Coreg)

Front 14

Neurotransmitter release inhibitors

Back 14

Guanetheline
Reserpine

Front 15

Catecholamines

Back 15

Epi, NOrepi, Isoproterol

Front 16

A1 agonists

Back 16

Phenylephrine
Pseudoephedrine (Sudafed)

Front 17

A2 Agonists

Back 17

A2=Clone of A
Clonadine (Catapress)
Apriclonidine (Iopidine)

Front 18

B1 Agonist

Back 18

Dobutamine (dobutrex)

Front 19

B2 Agonist

Back 19

Alberuterol

Front 20

Other Adrenergic Stimulants

Back 20

Ephedrine
Amphetamine
Methylphenidate-Ritalin
Cocaine
Tyramine

Front 21

DA agonists

Back 21

Dopamine
Fenodopam

Front 22

Bethanechol (urecholine)

Back 22

M-Cholinergic Agonist
increase bowel and bladder motility
urinary retention drug

Bath=Bowel and Bladder (no Brains)

Front 23

Pilocarpine (pilocar)

Back 23

M-cholinergic agonist
increase saliva and sweat(excessive)
BBB, Eye- cycloplegia.

S&S. Erector Pili next to sweat glands, then, of course you lick the sweat.

Front 24

Cevimelin (evoxac)

Back 24

M3- cholinergic agonist
increase sweat/saliva
Sjogrens Dry mouth- less effect on sweat gland

New York Jew "Sjogren" taking the Civeme-line train downtown.

Front 25

Carbachol

Back 25

M+N Cholinergic Agonist
Closest to ACh, doesn't cross BBB
effects both pre-post terminals

Front 26

Nicotine

Back 26

Nicotinic-Direct activation
Sympathetic and Parasympathetic action
Rapid desensitization of receptor- no secondary response shortly after
Poisoning a lot like Organophosphate
Low dose= alertness/attention
High dose= vomiting, tremors

Front 27

Varemicline (chantix)

Back 27

Nicotine partial agonist- decreases effects
Stop smoking drug
Nightmare farts

Front 28

Edrophonium

Back 28

Cholinesterase inhibitor
Used to diagnose myasthenia gravis
quick acting
can reverse NeuroMuscular Block

Front 29

Physostimin

Back 29

Cholinesterase inhibitor
Could be used for glaucoma-won't be
CNS side effects

EYE! So stick me!

Front 30

Echothiophate

Back 30

Cholinesterase inhibitor
Organophosphate
SLUDGE symptoms= poisoning

Eco-Phate (name says Organophosphate in it)

Front 31

Organophosphate pesticides

Back 31

Cholinesterase inhibitors
SLUDGE -2 PAM Atropine

Front 32

Donepezil

Back 32

Cholinesterase inhibitor
Alzheimers
Similar to physostygmine

Alzheimers pts are almost DONE!

Front 33

Scopolamine

Back 33

Cholinergic Agonist
Motion sickness patch
Oral= CNS effects, amnesia, sedation
old date rape drug

Get dizzy looking through a scope

Front 34

Tolterodine (Detrol)

Back 34

Cholinergic Agonist
M3 receptor
bladder incontenence in elderly
NO CNS effect

Sol/terodine - old and single if you're peeing your pants all the time

Front 35

Solifenacin (Versican)

Back 35

Cholinergic Agonist
M3 selective
overactive bladder and bladder spasms
No salivation effect

Sol/terodine

Front 36

Glycopyrorrolate (Robinul)

Back 36

Cholinergic antagonist
used in surgery to prevent vagal response when handling organs
Reduces neostigmine/edroponium effect

Robbin U Liver- sucka!

Front 37

Oxybutynin (Ditropan)

Back 37

Cholinergic Antagonist
Prevent bladder spasms post prostate surgery
closes bladder sphincter tight
NOT for BPH pts

Front 38

Dicyclomine (Bentyl)

Back 38

Cholinergic Antagonist
Antispasmodic for GI

you're not bentyl you're not crappin yourself.

Front 39

Ipratroprium (Atrovent)

Back 39

Cholinergic Antagonist
Bronchodilator in acute asthma/ CHF (inhaler)
quaternary amine- large- diesn't get to brain
Causes dry mouth

I Pray To Breathe

Front 40

Tropicamide (mydriacil)

Back 40

Cholinergic Antagonist
Short acting Mydriasis, cycloplegia

Mydriacil (seriously?)

Front 41

Diphenoxylate-Atropine (lomotil)

Back 41

Cholinergic antagonist
opioid w/atropine to treat diarrhea.

low#2- only two worded drug we have

Front 42

Anticholinergic side effects

Back 42

Dry mouth
Tachycardia in youth
Decreased GI control
mydriasis + cycloplegia

Front 43

D-Tubocurarine

Back 43

Non-Depolarizing Muscle Block
Long-acting
decrease plate potential
causes histamine release- hypotension/bronchospasm

Front 44

What drug releases histamine?

Back 44

D-tubocurarine

Front 45

Pancuronium

Back 45

NonDepolarizing Muscle block
Slow-long
ganglionic block w/ Muscarinic Vagal block- Tachycardia

Front 46

Vecuronium

Back 46

nonDepolarizing Muscle block
intermediate length action
Metabolized in the liver and products can be toxic

Front 47

Cisatracurium (nimbex)

Back 47

nonDepolarizing Muscle block
low toxicity, no histamine= POPULAR

Front 48

Rocuronium

Back 48

nonDepolarizing Muscle Block
Rapid acting intermediate effect
paralytic in surgery
immediate- contractures/fasiculations to paralysis
effect prolonged by cholinesterase inhibitors!

Front 49

Succinylcholine

Back 49

Nicotinic Depolarizing Muscle block
Rapid/short effect for trach/intubation
if prolonged causes desensitization
Size of twitch reduced, no reduce in height
Hydrolyzed by plasma pseudocholinesterase

Front 50

Mecamylamine (inversine)

Back 50

Gainglion blocker (only available)
Blocks sympathetic and parasympathetic
SO... TONE will determine response.

Front 51

Hexamethonium

Back 51

Prototype ganglia blocker- no sympathetic or parasympathetic response at all
no physical reaction

Front 52

Phentolamine

Back 52

alpha blocker
Reversible
decrease BP increase HR
decrease gastric secretion b/c of lack of serotonin
tachycardia, hypotension

Front 53

Phenoxybenzamine (dibenzylene)

Back 53

Alpha blocker
Irreversible
Epi reversal in pheochromocytoma (makes it more like isoproternol)
Tachycardia hypotension if hypovolemic

Front 54

Which alpha blocker (blocks both) is reversible vs irreversible?

Back 54

Phentolamine
Phenoxybenzamine
Say them backwards, can't say the longer one if my life depended on it

Front 55

Prazosin (minipress)

Back 55

Alpha 1 blocker
Reversible
relax A/V through a1
no change in HR- blocks reflex tach
First dose phenom

Front 56

Tamsulosin (Flomax)

Back 56

a1 blocker
a1a in prostate (specific)
no change in BP (for hypertensive pt)
Relaxes prostate bladder/sphincter for BPH
NO Ejac... sorry bro

Front 57

Yohimbine

Back 57

A2 blocker
increase NE/BP/HR
Antagonize clonidine
NOT for hypertension
Doesn't work

Front 58

Propanolol

Back 58

B1,2 blocker
Prototype blocker
Hyperthryroidism, Ischemic heart disease, Migraine
locla anesthetic (not for eyes)
don't stop quickly
problems with hypoglycemia
efects prolonged with cimetidine
shortened with phenobarb/phentoyn

Front 59

Metaprolol (lopressor)

Back 59

B1 blocker
Decrease HR
used in Hypertension, MI, migraine

Front 60

Esmolol (brevibloc)

Back 60

Beta1 blocker
short duration -8min
used IV during surgery

Front 61

Betaxolol (Betoptic)

Back 61

B1 blocker
Asthmatics
Glaucoma relief

Front 62

Nebivolol (Bystolic)

Back 62

Beta1 blocker
VasoD due to NO
Most B1 selective drug
decrease BP w/o decrease Lvent action
decreases cholesterol/glucose/triglycerides

Front 63

Pindolol (Visken)

Back 63

Beta w/ISA
local anesthetic
HTN in angina
lower bradycardia risk

Front 64

Acebutolol

Back 64

B1! w/ISA
local anesthetic
HTN in angina,
lower bradycardia risk

Front 65

What drugs also have local anesthetic properties that shouldn't be used in the eye?

Back 65

Pindolol
Acebutolol
Metoprolol
propanolol
Labetolol

Front 66

Caredilol (Coreg)

Back 66

A,B combo
VasoD, Decrease BP w/o Tachy
used for HTN, CHF, MI

ABs-Core muscles

Front 67

Guanethidine (Ismelin)

Back 67

NT release drug
inhibits NE release
displaces from vesicles
inhibited by cocaine

Front 68

Reserpine

Back 68

NT release drug
inhibits NE release
deplete NE/Epi/Dop/Ser/ from nerve terminals

Front 69

Metyrosine

Back 69

RLS in Dopamine synthesis
Decreases Norepi/Epi
Pre-surg drug for Pheochromocytoma

Front 70

Epinephrine

Back 70

Catecholamine, a1b1b2
Anaphylactic shock BronchoD
Vasopressor
Glaucoma- decrease aqueous humor
Not for ppl on B blockers, causes severe hypertension

Large dose- HTN hemmorhage, arrythmia

Front 71

Isoproternol

Back 71

Chatecholamine
Isolate B1 (b/c of large molecular size)
Increase HR, contractility, Vasodilates Sk M, decreases reflex brady

Front 72

Phenylephrine

Back 72

a1 agonist
vasoconstriction, increase bp w/ reflex
Decongestant w/ rebound effect
cautions w/ HTN patients
Causes Medriasis

Front 73

pseudoephedrine (sudafed)

Back 73

a1 agonist
decongestant without HTN

Front 74

Clonidine (catapress)

Back 74

a2 agonist
brain, decrease NE, decrease sympathetic response, decrease BP/HTN
for recovering addicts and hot flashes in menopause
excess= hypotensive
rapid withdrawal= hypertension

Front 75

apraclonidine (Iopidine)

Back 75

a2 agonist
decrease intraoccular pressure through a2 mediated vasoconstriction

Front 76

dobutamine

Back 76

B1agonist
INcrease Heart contractility/force
increase renin,
cardiac stress test- short acting

all those dopes can't even get out of bed we have to stress their hearts while they sit there.

Front 77

Albuterol

Back 77

B2 agonist
Relax respiratory sm m/ Uterine, BV to SkM
increases K uptake into muscle and increases glycogenolysis

Front 78

Ephedrine

Back 78

Adrenergic Stimulant
Not catecholamine
similar to NE,
CNS stimulant, bronchoDilator
causes HTN (ephedra)

Front 79

Amphetamine

Back 79

Not catecholamine
Indirect- displaces NE into synapses
Psychosis and tachycardia

Front 80

Methylphenidate (Ritalin)

Back 80

Not catecholamine,
like amphetamine
Paradoxical decrease in activity in ADHD disorder

Front 81

Cocaine

Back 81

Adrenergic Stimulant
inhibits reuptake of NE, addictive, causes HTN, stroke, arrythmia, MI, Psychosis

Front 82

Tyramine

Back 82

adrenergic stimulant
indirect- displaces NE from nerve ending, hydroxylized by MAO
if taking MAOinhibitors and eat lots of tyramine= Hypertension emergency

Front 83

Dopamine

Back 83

DA agonistf
low dose- D1 receptors on renal vasculature- vasoD/increased flow
High dose-B1 stimulation-> positive inotropy similar to epi-> nausea and vomiting

Front 84

Fenoddolpam (Corlopam

Back 84

D1 agonist
dilation of vascular bed
decreases BP short term for severe HTN tx