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16 Cards in this Set

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What are the three Antiplatelet drugs/classes?
Aspirin
Dipyridamole+Aspirin
ADP-Inhibitors
What are the two Anticoagulant drugs/classes?
Heparins
Warfain (Coumadin)

"New oral drugs" - Dabigatran, Rivaroxaban
Aspirin
Dipyridamole+Aspirin

treat?

ADRs?
Antiplatelet

low dose ("cardiac dose") better antiplatelet
(81mg - baby aspirin)
upto 325mg

Antiplatelet

ADRs: GI bleeding, ulcers
ADP-Inhibitors

treat?
Unique?
ADRs?
"...grel..."

Antiplatelet (platelets can't adhere)

"MORE POWERFUL THAN ASPIRIN"

Excessive Bleeding
Heparin

treat?
Unique?
ADRs?
Anticoagulants

Venous Thrombembolism (VTE)

DOES NOT BREAK UP A CLOT; allows body to dissolve

ADRs: excessive bleeding, HAT, HIT
Risk Factor: INR>4
Warfarin (Coumadin)

MOA:
Blocks Vitamin K
(i.e. Liver can NOT make clotting factors)
What makes newer oral drugs better than Warfarin?
Dabigatran
Rivaroxaban

new: Vitamin K interaction (don't monitor INR)
EXPENSIVE
Warfarin (Coumadin)

Treats:

ADRs
Prophylaxis: DVT / PE (Pulmonary Embolism) ADRs: BLEEDING GI problems Purple Toe Syndrome NEED: Vitamin K supplements
Prophylaxis: DVT / PE (Pulmonary Embolism)

ADRs: BLEEDING
GI problems
Purple Toe Syndrome

NEED: Vitamin K supplements
Warfarin (Coumadin)

Drug Interaction
Many p450 interaction

NO NO NO NSAIDs!

LIMIT Vitamin K intake!
Warfarin (Coumadin)

PATIENT INTERACTION
Wear medical bracelet
Check PT/INR
NONONONONONON NSAIDs
Limit Vitamin K

Limit: Alcohol/pregnancy/Herbals
antidotes for warfarin
Vitamin K injection

plasma (for immediate)
List foods rich in vitamin K and patient instructions for vitamin K in the diet.
green leafy veggies
List OTC products likely to contain “hidden” NSAIDs and/or vitamin K
cough & cold products: aspirin / NSAIDs

other "foods"
Interpret the meaning of an elevated INR vs. a low INR
high INR = risk of bleeding
Signs and Symptoms:

Clot
short breath
chest pain
tenderness
swelling in legs
List the pain medications safe to take with warfarin and those that are contraindicated
Acetaminophen (Tylenol)

DO NOT TAKE:
NSAIDs/Aspirin