Pharm Exam 1, 2014

Front 1

BP compensation pharmacological interventions:

Back 1

vasoconstrictors (norepi) and cardiotonic agents (dopa)

Front 2

_________ via normal homeostatic response includes increased aldosterone and ADH.

Back 2

BV compensation

Front 3

BV compensation pharmacological interventions:

Back 3

Whole-blood, crystalloids (5% dextrose/H2O), colloids (albumin)

Front 4

Colloids cannot enter ____ like crystalloids can.

Back 4

Cells

Front 5

Maintains plasma osmotic pressure, transports substances thru blood.

Back 5

MOA of colloids

Front 6

Primary use of colloids.

Back 6

Restoration of plasma volume and blood proteins

Front 7

Plasmanate, dextrans, serum albumin. They expand plasma volume and maintain blood pressure. What type of fluids are these?

Back 7

Colloids

Front 8

NS, LR, plasmalyte, hypertonic saline. Have concentrations of lytes resembling those of plasma

Back 8

Crystalloids

Front 9

Crystalloid MOA:

Back 9

Can readily leave blood and enter cells to expand blood and cell volume

Front 10

Primary use of crystalloids is to ______ fluids that have been lost and to promote _____:

Back 10

Replace; u/o

Front 11

Adverse effects of vasoconstrictors;sympathomimetics:

Back 11

tachycardia and hypertension

Front 12

MOA: strongly activate alpha-adrenergic receptor to increase bp; increase cardiac contractility via beta-receptors (positive inotropic effect)

Back 12

Vasoconstrictors/sympathomimetics (norepi)

Front 13

Primary use is to tx hypovolemic and cardiogenic shock. Adverse effects of arrhythmias, HTN, and gangrene.

Back 13

Inotropic agents

Front 14

Inotropic agents prototype drugs.

Back 14

Dopamine, dig, dobuta

Front 15

MOA of inotropic agents: increase intracellular ______ and strength of _____ which leads to increased CO.

Back 15

Ca; cardiac contraction

Front 16

Low dose dopa; dopaminergic effect, 'renal dose'

Back 16

2-5 mcg/kg /min

Front 17

High dose dopa; B-adrenergic effect, increase CO/BP

Back 17

5-10 mcg/kg/min

Front 18

Extremely high dose; 'pressor dose'

Back 18

10-20 mcg/kg/min

Front 19

Constriction of BSM, decreased CO, VD, and increased leakage from BV all occur during:

Back 19

Anaphylaxis

Front 20

Adverse effects of epi.

Back 20

HTN, arrhythmias

Front 21

MOA: use as nonselective adrenergic agonist --> vasoconstriction and increased cardiac contractility. Use in anaphylaxis.

Back 21

Epi