Pharm Ati

Front 1

Tylenol uses

Back 1

Pain
Fever

Front 2

Tylenol action

Back 2

Slows production of prostaglandins in the CNS

Front 3

Side effects of Tylenol

Back 3

Liver damage
Early signs- N/V/D, sweating, and abdominal discomfort progressing to liver failure, coma and death.

Front 4

Limit on Tylenol per day

Back 4

4gm

Front 5

Antidote to Tylenol

Back 5

Mucomyst
(Acetylcystine)

Front 6

Medication/food interactions for Tylenol

Back 6

Alcohol (Inc. liver damage)
Warfarin (Slows metab of warfarin leading to inc levels)

Front 7

Examples of Morphine Sulfate

Back 7

Fentanyl, Demerol, Codiene, oxycodone

Front 8

Morphine action

Back 8

Acts on Mu receptors. Produces analgesia, resp depression, euphoria, and sedation.

Front 9

Morphine uses

Back 9

Pain, sedation, reduction of bowel motility

Front 10

Side effects of Morphine

Back 10

Resp depression, constipation, orthostatic hypotension, urinary retention, cough suppression, Sedation, biliary colic, emesis, opioid overdose.

Front 11

Morphine is contraindicated in

Back 11

Premature infants

Front 12

Repeated use of demerol results in

Back 12

Accumulation of normeperidine. This can cause seizures and nephrotoxicity. No more than 600mg/24 hours.

Front 13

Med/food interactions for Morphine

Back 13

CNS depressants, anticholonergic agents, MAOI's, Antihypertensives

Front 14

Hold morphine if respirations are less than

Back 14

12

Front 15

Morphine reversal

Back 15

Narcan

Front 16

Fentanyl is _____x stronger than morphine

Back 16

100

Front 17

Morphine classification

Back 17

Opioid agonist

Front 18

Pentazocine (Talwin)
Butorphanol (Stadol)
Classification

Back 18

Agonists- antagonist opioid

Front 19

Action of Agonists- antagonist opioids

Back 19

Antagoists to mu receptors = analgesia, euphoria, resp depression, sedation, dependance and decresed GI.
Agonist to kappa = analgesia, sedation and decreased GI.

Front 20

Agonist- antagonist opioids are used for

Back 20

Mild to mod pain

Front 21

Side effects of agonist-antagonists

Back 21

Abstinence syndrome (cramping, hypertension, and vomiting)

Front 22

Example of opioid antagonist

Back 22

Narcan

Front 23

What is the action of Narcan?

Back 23

Competes for opioid receptor sites

Front 24

What is narcan used for?

Back 24

To reduce effects of opioids such as resp depression, treatment of opioid overdose

Front 25

Side effects of Narcan

Back 25

Tachycardia, tachypnea, abstinence syndrome

Front 26

Adjuvant medications for pain
Examples

Back 26

Tricyclic antidep- Elavil
Anticonvul- Neurontin, dilantin
CNS stim- Ritalin
Antihistam- Vistaril
Glucocortico- Decadron, deltasone
Biphosph- Aredia, etidronate

Front 27

Action of adjuvant medications

Back 27

Enhance the effects of opioids- Allows for lower doses of opioids

Front 28

Uses of adjuvant medications

Back 28

Neuropathic pain, cancer related conditions, relieves symptoms that aggravate pain

Front 29

Side effects of tricyclic antidepressants

Back 29

Orthostatic hypotension, sedation, anticholonergic effects

Front 30

Side effects of anticonvulsants

Back 30

Bone marrow suppression

Front 31

Side effects of CNS stimulants

Back 31

Weight loss and insomnia

Front 32

Antihistamine side effects

Back 32

Sedation

Front 33

Glucocorticoid side effects

Back 33

Adrenal insufficiency, osteoporosis, hypokalemia, glucose intolerance, PUD

Front 34

Biphosphonate side effects

Back 34

Flu like symptoms, venous irritation and IV site

Front 35

Examples of antigout medication

Back 35

Colchicine, allopurinol, indocin, probenecid

Front 36

Colchicine action

Back 36

Decreases inflammation by preventing infiltration of leukocytes

Front 37

Allopurinol action

Back 37

Inhibits uric acid production

Front 38

Probenecid action

Back 38

Inhibits uric acid reabsorption by the renal tubules

Front 39

Side effects of colchicine

Back 39

GI toxicity, abdominal pain, N/V/D

Front 40

Side effects of probenecid

Back 40

Renal injury

Front 41

Med/food interactions with allopurinol

Back 41

Warfarin (slows metabolism)

Front 42

Med/food interactions with probenecid

Back 42

Salicylates- lessens the effectiveness of probenecid

Front 43

Foods to avoid with antigout medications

Back 43

Alcohol and foods high in purine

Front 44

Side effects of Ergot alkaloids

Back 44

GI discomfort, Ergotism (muscle pain, cold pale extremities), phy dependence, abortion

Front 45

Side effects of serotonin receptor antagonists

Back 45

Chest symptoms, coronary vasospasm, tetrogenic

Front 46

Side effects of beta blockers

Back 46

Tiredness, fatigue, depression, and asthma exac

Front 47

Anticonvulsant side effects

Back 47

Neural tube defects

Front 48

Tricyclic antidepressant side effects

Back 48

Anticholonergic effects

Front 49

Calcium channel blocker side effects

Back 49

Orthostatic hypotension, constipation

Front 50

Contraindications of ergotamine

Back 50

Renal or liver dysfunction, sepsis, CAD, and pregnancy

Front 51

Medications for rheumatoid arthritis
Examples

Back 51

DMARDS
Glucocorticoids
Immunosuppressants
NSAIDS

Front 52

Action of DMARD

Back 52

Slows joint degeneration and progression of RA

Front 53

Side effects of cytotoxic agents

Back 53

Hepatic fibrosis, bone marrow supression, GI ulceration, fetal death

Front 54

Side effects of gold salts

Back 54

Toxicity, blood dyscrasias, hepatitis, GI discomfort

Front 55

Antimalarial side effects

Back 55

Retinal damage

Front 56

The gold standard opioid used for mod to severe pain?

Back 56

Morphine sulfate

Front 57

80-100 times more potent than morphine

Back 57

Fentanyl

Front 58

Opioid used for cough suppression

Back 58

Codiene

Front 59

Tricyclic depressant used for neuropathic pain

Back 59

Amitriptyline (Elavil)

Front 60

Imitrex is contraindicated for clients with

Back 60

CAD

Front 61

Which opioid should not be used for more than 48 hours?

Back 61

Demerol

Front 62

Treatment of parkinsons requires what two main classes of medications?

Back 62

Meds that activate dopamine receptors
Meds that block acetylcholine receptors

Front 63

Three main meds to treat bipolar

Back 63

Lithium, valproic acid, and cabamazepine

Front 64

Examples of neuromuscular blocking agents

Back 64

Tubocurarine- Nondepolarizing
Succinylcholine- Depolarizing

Front 65

Why are neuromuscular blocking agents used?

Back 65

Used as adjuncts to general anesthesia to promote muscle relaxation.
Used to control spontaneous resp movements in clients on the vent.

Front 66

Succinylcholine is the preferred agent for (3)

Back 66

Seizure control during electroconvulsive therapy, ET intubation, endoscopy

Front 67

Side effects of succs

Back 67

Low pseudocholinesterase leads to apnea, malignant hypothermia, hyperkalemia and after 12-24 hours post op may result in muscle pain in upper body and back.

Front 68

Med/food interactions for neuromuscular blocking agents

Back 68

General anesthesia, aminoglycosides, tetracycline, neostigmine and other cholinesterase inhibitors.

Front 69

Examples of dopaminergics

Back 69

Levodopa, Sinmet, Levodopa Carbidopa

Front 70

What does Levadopa do?

Back 70

Crosses blood brain barrier and is taken up by dopaminergic nerve terminals and is converted to dopamine. DA is then released into synaptic space and causes stim of DA receptors.

Front 71

What does carbidopa do?

Back 71

Inhibits conversion of levadopa to DA in intestine and periphery and allows more levadopa to reach the CNS.

Front 72

Examples of Dopamine agonists

Back 72

Mirapex, Requip, Parlodel

Front 73

What do dopamine agonists do?

Back 73

Act directly on DA receptors

Front 74

Examples of centrally acting muscle relaxants

Back 74

Valium (Diazepam)
Baclofen
Flexeril
Skelaxin

Front 75

Action of centrally acting muscle relaxants

Back 75

Acts in the CNS to enhance GABA and produce sedative effects

Front 76

Examples of peripherally acting muscle relaxants

Back 76

Valium
Baclofen
Dantrium

Front 77

Action of peripherally acting muscle relaxants

Back 77

Depresses spacticity

Front 78

What are side effects of lidocaine?

Back 78

Spinal headaches and urinary retention

Front 79

Action of clozaril, risperdal, zyprexa, seroquel, abilify

Back 79

Blocks serotonin and dopamine receptors. Also blocks receptors for norepi, histamine, and acetylcholine.

Front 80

Examples of SSRI's

Back 80

Lexapro, celexa, zoloft, paxil, prozac