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13 Cards in this Set
- Front
- Back
Dinoprstone: (Cervidil)
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-Class: Prostaglandin analog, “Abortifiacient”, Pregnancy Category “C”
-Therapeutic Use: Cervical ripening or termination of pregnancy from weeks 12-20. -Important Side Effect: Bradycardia/syncope, abnormal uterine contraction, bronchospasm, headaches/ flushing, blurred vision. -Important Interactions: Augments the action of Oxytocin agents |
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Carboprost:
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-Class: Analog of PGF2a
-Therapeutic Use: Controls postpartum bleeding -Important Side Effect: vasospasm, potential increase in BP -Important Interactions: Diarrhea |
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Alprostadil:
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-Class: PGE1 agonist
-Therapeutic Use: Maintain patent ductus arteriosus and treatment of ED -Important Side Effect: Bradycardia, hypotension, CHF, seizures, diarrhea, penile pain -Important Interactions: none |
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Epoprostenol:
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-Class: Analog of PGI-1
-Therapeutic Use: long term treatment of pulmonary HTN. -Important Side Effect: Headaches, dizziness, diarrhea, mylagia, flushing and tachycardia -Important Interactions: increased risk of bleeding w/ anti-coagulants |
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Remodulin
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Prostacyclin analog approved for continuous infusion in 1o Pulmonary HTN.
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Misoprostol:
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-Class: Prostaglandin analog, “Abortifacient”, Pregnancy Category “X”
-Therapeutic Use: Prevent PUD in NSAID users and Rx of ulcers unresponsive to H2 antagonists. -Important Side Effect: headache, diarrhea, cramps and uterine contractions -Important Interactions: none |
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Latanoprost:
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-Class: analog of PGF2a (agonist)
-Therapeutic Use: Reduction of IOP in open-angle glaucoma and ocular HTN -Important Side Effect: Increased melanin = increased brown color in iris -Important Interactions: few if administered properly – effects restricted to the eye. |
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Bimatoprost:
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-Class: analog of PGF2a (agonist)
-Therapeutic Use: Reduction of IOP in open-angle glaucoma and ocular HTN -Important Side Effect: Increased melanin = increased brown color in iris -Important Interactions: few if administered properly – effects restricted to the eye. |
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Travoprost:
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-Class: analog of PGF2a (agonist)
-Therapeutic Use: Reduction of IOP in open-angle glaucoma and ocular HTN -Important Side Effect: Increased melanin = increased brown color in iris -Important Interactions: few if administered properly – effects restricted to the eye. |
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Unoprostone:
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-Class: analog of PGF2a (agonist)
-Therapeutic Use: Reduction of IOP in open-angle glaucoma and ocular HTN -Important Side Effect: Increased melanin = increased brown color in iris -Important Interactions: few if administered properly – effects restricted to the eye. |
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Montelukcast:
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-Class: Leukotriene Cys LT1-antagonist
-Therapeutic Use: Asthma (1 x day) -Important Side Effect: well tolerated, may cause diarrhea, laryngitis, otitis, sinusitis, and nausea -Important Interactions: avoid in NSAID-sensitive patients. Chewable tablets contain Phenylalanine. |
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Zafirlukast:
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-Class: Leukotriene Cys LT1-antagonist
-Therapeutic Use: Asthma (2x day) -Important Side Effect: Same as Montelukast, plus rash and/or neuropathy similar to Churg-Strauss -Important Interactions: Increases Warfarin effects, erythromycin and theophylline decrease Zafirlukast [], Aspirin increases [] of Zafirlukast. |
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Zileuton:
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-Class: 5-Lipoxygenase inhibitor – inhibit leukotrienes synthesis
-Therapeutic Use: Asthma prophylaxis -Important Side Effect: well tolerated, may cause headaches -Important Interactions: Zileuton increases the plasma [] of Propranolol, Theophylline, and Warfarin |