Pharm 236 Chapter 28

Front 1

__________ are male sex hormones secreted by the testes in men the ovaries of women, an the adrenal cortex of both sexes.

Back 1

Androgens

Front 2

Like the female sex hormones the naturally occurring male sex hormones are steroids synthesized from__________

Back 2

Cholesterol

Front 3

The androgens produced by the ovaries have little androgenic activity and are used mainly as precursor substances of the production of naturally occurring _____________

Back 3

estrogen

Front 4

The adrenal glands produce several androgens including ____ and dhyroepiandrosterone DHEA

Back 4

Androstenedione

Front 5

__________ is normally the only important male sex hormone.

Back 5

Testosterone

Front 6

Given to women to antagonize or reduce the effects of female sex hormones.

Back 6

Male sex hormones

Front 7

Synthetic drug with weak androgenic activity

Back 7

Danazol

Front 8

Extensively metabolized in its first pass through the liver

Back 8

Oral testosterone

Front 9

Given my injection because they are metabolized rapidly by the liver if given orally.

Back 9

Naturally occurring androgens

Front 10

Drugs with slow onsets of action and lasting 2 to 4 weeks

Back 10

Intramuscular IM testosterone cypionate and testosterone enanthate

Front 11

What is the function of testosterone as it relates to the male?

Back 11

The main function of testosterone are related to the development of male sexual characteristics reproduction and metabolism.

Front 12

Describe the function of anabolic steroids.

Back 12

Anabolic steroids are synthetic drugs with increased anabolic activity and decreased androgenic activity compared with testosterone. They were developed during attempts to modify testosterone so that its tissue building and growth stimulating effects could be retained while its masculinizing effects could be eliminated or reduced.

Front 13

What are the negative effects of anabolic steroids when used by adolescents?

Back 13

Anabolic steroids can stop bone growth and damage the heart kidneys and liver of adolescents.

Front 14

Identify the liver disorder related to anabolic steroid use.

Back 14

Liver disorder include benign and malignant neoplasms cholestatic hepatitis and jaundice and peliosis hepatitis a disorder in which blood filled cysts develop in the liver and may lead to hemorrhage or liver failure.

Front 15

Michael Smith age 6, is prescribed androgens for a diagnosed deficiency. You arrange for x rays every 6 months because androgens may cause what to happen?

Back 15

Premature epiphyseal closure

Front 16

Androstenedione and DHEA, androgens produced by the ______________ are also available as over the counter dietary supplements.

Back 16

Adrenal cortex

Front 17

Because of their abuse protential androgens and anabolic steroids are classified as what type of substances?

Back 17

Schedule III controlled substances

Front 18

Androgens and anabolic steroids are used to enhance anthletic performance and are termed ergogenic. What are the effects they have?

Back 18

They cause a decrease in musculature and increase in muscle mass.

Front 19

The main functions of testosterone are related to the development of male sexual characteristics reproduction and what other functions?

Back 19

Metabolism