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11 Cards in this Set
- Front
- Back
Nitrous Oxide
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MOA: blocks glutamate
no odor/taste, adjunct use only, rapid and not toxic (dental only) hypoxia if used alone |
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Halothane (Fluothane)
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MOA: enhance GABA and glycine, block nicotinic R's
rapid induction, no bronchospasm, hypotension, uterine relaxation for fetus extraction Halothane Hep (no longer used) |
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Enflurane (Ethrane)
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MOA: enhance GABA and glycine, block nicotinic R's
similar to halothane but less cardiac effects, cerebral effects, inc. mm relax (avoid OB), more rapid chance of seizure |
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Isoflurane (Forane)
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MOA: enhance GABA and glycine, block nicotinic R's
similar Enflurane, less inotropic effects, CV safety better, depth of anesthesia controlled better pungent odor, most widely used, neuro espc. |
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Methoxyflurane (Metofane)
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MOA: enhance GABA and glycine, block nicotinic R's
very rapid, most potent, no uterine relax (good OB) nephrotoxic metabolites, use for short times only |
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Thiopental (Barb)
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I.V.
MOA: binds GABAb2, increase GABA inhibition produces effect within one circulation to the brain high lipid solubility so fast in and fast out redistribution is reason so short acting |
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midazolam (Benzo)
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I.V.
MOA: bind GABAa1,a2 increases GABA fastest onset of action also used as premedication as good for producing amnesia |
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fentanyl (opioid)
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I.V.
MOA: used most particularly in cardiac surgery withlittle cardiovascular effects |
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Propofol
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I.V.
MOA: used mostly for day surgery as faster recovery than barbiturates or benzos |
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Etimodate
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I.V.
MOA: sedative-hypnotic used for induction, but get pain at injection site and vomiting |
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Ketamine
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I.V.
MOA: get catatonia, analgesia, and amnesia due to blockade of NMDA receptor |