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8 Cards in this Set

  • Front
  • Back
General model for deliverting scientifically grounded medical care
Generalizable scientific knowledge + particular pt leads to a measurable outcome

Explore a method for summarizing evidence is what you do to attain generalizable scientific knowledge

To integrate the knowledge and pt you must hear stories about applying this information in clinical care.
Quality of evidence hierarchy
Lowest to highest

At least one RCT
Controlled trials without randomization
Cohort of case-control studies
Multiple time series or dramatic results
Agreement among respected authorities.
Quality of evidence grades
A - Found good evidence that the service improves health - benefits outweight harms

B - Fair evidence...

C - Balance of benefits and harms are too close to tell

D - Service is ineffective and harms outweight benefits

I - Service is bad.
What EBM is NOT
Common practice

impossible to practice

culinary medicine

a cost cutting strategy

restricted to randomized clinical trials and meta-analyses.
How to practice evidence based medicine
Formulate a clinical question

Find the best evidence

Eval and summ that evidence

Apply to clinical care

Evaluate performance.
Categories of clinical questions
Dx test - test accuracy
Px - Risk
Tx - effectiveness
Framing an answerable question
Define the pt or clinical problem
What is the test or intervention?
Who is the comparison group?
Define diagnosis or outcome
The things that make up a treatment question:
Patient or clinical problem
“In this postmenopausal woman with possible early osteoporosis”

Intervention
“is the addition of alendronate”

Comparison
“compared to current treatment with estrogen, calcium and Vitamin D”

Diagnosis or Outcome
“associated with a stabilization of her bone density?”