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47 Cards in this Set

  • Front
  • Back

risk factors for fracture (age < 50)

-fragility fractures


-use of high-risk medications


-hypogonadism


-malabsorption syndromes


-chronic inflammatory conditions


-perimary hyperparathyroidism


-other disorders strongly associated w rapid bone loss or fractures

risk factors for fracture (age 50-64)

-fragility fx after age 40


-prolonged use of glucocorticoids or other high risk medications


-parental hip fx


-vertebral fx or osteopenia identified on radiography


-high alcohol intake or current smoking


-low body weight (<60kg) or major weight loss (>10% of body weight at age 25)


-other disorders strongly associated w osteoporosis

dietary sources of calcium

milk


cheese


yogurt


ice cream


tofu with calcium sulphate


white beans


almonds


sardines


salmon


rice or soy beverage


fortified orange juice


broccoli


orange

calcium in 1 cup milk

300mg

calcium in 50g hard cheese

370mg

calcium in 1/4 cup almond

90mg

calcium in 1 med orange

50mg

calcium in 1/2 cup fortified orange juice

185mg

how much calcium in Tums regular

200mg elemental per

how much calcium in caltrate

600mg elemental

how much calcium in citracal

200mg elemental

how much calcium in citracal + D

315mg elemental

how much vit D in caltrate600 + D

800 IU

how much vit D in caltrate plus

800 IU

how much vit D in citracal + D

200 IU

health canada calcium requirements:


51-70 y/o

males: 1000mg


females: 1200mg

health canada calcium requirements:


> 70 y/o

1200mg

health canada calcium requirements


pregnancy/lactation

14-18 y/o: 1300mg




16-50 y/o: 1000mg

health canada vit D requirements:


9-70 y/o

600 IU

health canada vit D requirements


> 70 y/o

800 IU

health canada vit D requirements


pregnancy/lactation

600 IU

vit D: canadian pediatric recommendations

premature infants:


-200 IU/kg/d


-max 400 IU/d




infants first year:


-400 IU/d


-increase to 800IU/d from oct-april for those living north of 55th parallel (edmonton)




infants and children should be exposed to sunlight for short periods (15min/d)




suggest considering 2000IU daily to pregnant and lactating women

dietary sources of vit D

milk


rice or soy beverage


fortified orange juice


egg yolk


sockeye salmon, canned


atlantic sardines


pacific sardines


tuna

vit D in 1 cup milk

100 IU


vit D in 1/2 cup fortified orange juice

50 IU

vit D in 75g sockeye salmone

585IU

vit D in 1 egg yolk

25 IU

calcium carbonate % elemental calcium

40%

calcium citrate % elemental calcium

21%

calcium gluconate % elemental calcium

9%

calcium carbonate pros

inexpensive


contains highest amount of elemental calcium


well absorbed by most of the popn




to enhance abs:


-take w food (comparable abs to calcium citrate)


-take in divided doses (can only abs 500mg/dose)

calcium carbonate cons

SE:


-flatulence, bloating, constipation

calcium citrate pros

-pH independent


-less carbon dioxide production




recommended for pts w:


-achlorhydria


-kidney stones


-intolerable gas w carbonate

calcium citrate cons

more expensive than carbonate in general




avoid in chronic renal failure


-binds albumin in dialysis soln

coral calcium

contains: calcium carbonate, magnesium, trace amounts of other minerals


-claimed to be from coral reefs




marketed as:


-a calcium w superior absorption


-a panacea for Alzehimer's, cancer, diabetes, fibromyalgia


-claimed that low body pH causes these conditions and that coral calcium increases pH




no benefit

milk-alkali syndrome

-historically occurred w ingestion of large amounts of calcium and an absorbable alkali (eg sodium bicarbonate) leading to hypercalcemia




today more likely w inappropriate high doses of calcium carbonate


- >4000mg elemental calcium/d


-cases have occured w 1000-1500mg elemental calcium/d


-recent resurgence in geriatric popn




usual presentation: hypercalcemia, metabolic alkalosis, imparied renal fxn


-sn/sx hypercalcemia: fatigue, depression, mental status changes, N/V/C, urinary frequency, ECG changes, arrhythmias




large amounts of milk or dairy products are not necessary for this condition to develop

kidney stones

4 types: calcium, uric acid, struvite, cysteine




most kidney stones made of caclium oxalate


-precipitation of calcium oxalate crystals in the urine


-increased oxalate likely cause of kidney stones




dietary calcium binds oxalates in the GIT


-limits their abs and prevents their precipitation in the kidney




low calcium diet increases oxalate in the urine

advise kidney stone pts to:

-limit sources of oxalate (beet greens, rhubarb, sorrel, nuts, berries, spinach, chocolate)


-continue w calcium intake (dietary more protective?)


-calcium citrate may have protective effect

pts who may be at risk for lead toxicity

renal failure pts using large amounts of calcium acetate

lead contamination

lead is a natural component in many foods and supplements




a serving of raisins, grapes, berries, wine, or leafy greens contains more lead than a typical calcium supplement

lead content in calcium supplements

per 1500mg elemental calcium/d:


-caltrate > 3mcg


-nature made (oyster shell) 1.95mcg


-oscal 1.74mcg


-Tums below level of detection

sx of calcium toxicity

-increased thirst


-urinary frequency


-nocturia


-anorexia


-nausea


-lightheadedness


-mental confusion

foods/medications that may interact w calcium

-Phytates (bran, metamucil, soybeans, seeds)


-some Abx (quinolones, tetracyclines)


-thiazide diuretics


-bisphosphonates


-L-thyroxine


-iron

magnesium benefit

has a role in bone and teeth formation




possible benefits of concurrent use w calcium


-laxative effect > 350mg


-concurrent ingestion w calcium does not seem to affect abs or either mineral

sources of magnesium

-whole grains


-green leafy vegetables


-nuts


-seafood

magnesium DRI

320-420mg

vit K recommendations

-not recommended for prevention of post-menopausal osteoporosis


-not recommended for tx of postmenopausal osteoporosis


-not recommended for use in men or premenopausal women