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19 Cards in this Set

  • Front
  • Back

irritant herbal laxatives

-cascara sagrada bark


-rhubarb root



bulk forming herbal laxatives

psyllium husks


-flax seed

laxative efficacy

likely quite effective short term

laxative safety

-dependence (poor gastric motility, diarrhea and non-functioning colon)


-alteration of ADME of drugs/nutrients


-hypokalemia




do not recommend irritant laxatives for more than 1-2 weeks

laxative CI

GI conditions (obstruction, inflammation, ulcers)

diuretic efficacy

likely quite effective short term

diuretic safety

hypokalemia




not to be used long term

conjugated linoleic acid (CLA) efficacy

may decrease body fat and lead to leaner body (CS?)

CLA safety

generally well tolerated (up to 2 years in study)


no known drug interactions




caution: diabetic pts (may increase insulin resistance)

pyruvate efficacy

modest weight and fat loss (when combined w diet and exercise!!)

pyruvate safety

GI upset (gas, bloating, diarrhea)




safe short term (6wk)

bitter orange efficacy

mixed results when used in combination products with caffeine and SJW

bitter orange safety

-significant increase in HR, but not BP (only increased w addition of caffeine)

bitter orange DI

other stimulants




selectively inhibits cyp3a4


-avoid: MAOIs (may increase BP effects of synephrine), cyp3a4 substrates

bitter orange CI

avoid in CV patients


-hypertension


-prolonged QT-interval


-tachyarrhythmias




these effects w caffeine

Garcinia cambogia hydroxycitric acid (HCA) efficacy

-weight loss (mixed)


-decrease appetite??

Garcinia (HCA) DI

avoid serotonergic drugs

Glucomannan/PGX efficacy

small weight loss observed; clinically significant?

glucomannan/PGX safety

space meds


decrease BG


GI obstruction?




drink lots of water