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44 Cards in this Set
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- Back
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Psorasis Tx |
Coal tar, anthralin, CS, Vit D Resistent: UVB, Psoralen + UVA, retinoids, MTX, cyclosporine |
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2-10 cm red scaly patch followed by generalized eruption of pink oval scaly itchy patches over trunk & UEs |
Pityriasis Rosea - herald patch followed by Christmas tree distribution |
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Pityriasis Rosea Tx |
Self-limited - 6-12 weeks Sx'tic Tx - topical CS, oral anti-histamines, UVB/sunlight |
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Eczema Tx |
topical CS, skin care |
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Contact dermatitis Tx |
Topical CS, dressing soaked in Burow's solution (aluminum acetate) |
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Greasy erythematous scaling - Tx? |
Seborrheic dermatitis Tx: selenium sulfide, pyrithione zinc or ketoconazole-containing shampoos, topical corticosteroids. |
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Oral blisters that rupture easily Months later - bullae that emerge and rupture, leaving eroded crusted surfaces |
Pemphigus Vulgaris |
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Pemphigus Vulgaris pathophys |
Abs to surface GPs that hold epidermal cells together --> intraepidermal blisters
Look for IgG deposits by IF for Dx |
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Pemphigus Vulgaris Tx |
Systemic CS, immunosuppressive agents |
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Causes of erythema multiforme |
Drugs - penicillin, sulfonamides, barbiturates, NSAIDs, thizaides, phenytoin, vaccinations Viruses - HSV, Hep A & B Bacteria - strep Fungi, mycoplasma, cancer, radiotherapy, pregnancy Idiopathic |
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Erythema multiform + mucosal membranes + ocular Sx (uveitis / conjuctivitis) |
SJS (EM major) |
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Prodrome flu-like Sx Widespread, full thickness necrosis of skin covering > 30% of body surface
Complications? Tx |
TEN Complications - 2' skin infections, fluid/electrolyte abnl, pre renal azotemia, 30% mortality
Tx - Remove causitive agent, hospitalize, fluid/electrolyte replacement, systemic CS |
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Impetigo bugs
Tx |
S. aureus (bullous lesions) GAS (nonbullous lesions)
Tx- soak in warm water to remove crusts, benzoyl peroxide, topical or oral Ab depending on severity |
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Warm, tender, red, edematous skin, non elevated borders
Bugs? Tx? |
Cellulitis S. aureus, GAS, H. flu
Oxacillin or 1st gen cephalosporin (Cephalexin = Keflex) MRSA - vanc H. flu - ceftriaxone |
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Red / tender skin w/ flaccid bullae --> sloughs off Widespread Kids < 2 yo
Tx |
Staph scalded skin syn Clinical Dx, but if Cx need to Cx site of colonization (nose, eyes, throat), not skin
Tx - hospitalize if extensive, deride, oxacillin or dicloxacillin, IV fluids if severe |
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Pink exanthem appears on upper trunk 12-48 hrs after onset of fever --> spreads to extremities and becomes sandpaper rash --> fades in 4-5 days & desquaminates
Bug & drug |
Scarlet Fever GAS Penicilin, macrolide, cephalosporin |
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Single or multiple 2-5 mm firm, umbilicated pearly-white papules |
Molluscum contagiosum
Multiple facial lesions --> think HIV |
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Spaghetti & meatball on KOH |
Tinea versicolor |
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Annular lesions with peripheral scale & central clearing |
Tinea corporis (ringworm) |
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Bright green fluorescence of hair shaft under Wood's lamp |
Tinea capitis |
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Tinea Tx's |
Topical antifungals - imidazoles & terbinafine Systemic if unresponsive or nail / hair involvement (griseofulvin, terbinafine) Topical CS if severe pruritus |
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Intensely pruritic, small red macule or papule w/ central hemorrhagic punctum on shoulders, trunk or butt
Tx |
Pediculosis corporis - body lice
Permethrin rinse, pyrethrin or lindane |
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Raised, red, serpiginous tracts on extremities or butt
Tx |
Cutanous larva migrans - from dog or cat hookworm
Tx - self-limited or give thiabendazole |
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Multiple types of lesions - 1-2 mm red papules (pruritic), threadlike burrows
Tx |
Scabies
Lindane - leave on for 8-12 hours - Neurotoxic - avoid w/ infants
Permethrin or sulfur ointment |
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Palpable purpura, arthritis, abd pain
Tx? |
HSP - IgA mediated vasculitis, commonly follows strep or viral infections
Usually self-limited, CS if severe, monitor for renal dysfunction
May see intussussception |
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Vitiligo Tx |
Psoralen + UV therapy
Topical steroids for areas like lips that aren't good for phototherapy. |
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Blue-gray macules in nonwhite infants |
Mongolian spots - melanocytes arrested in migration from neural crest to epidermis. Most resolve w/ in first few years; some never due |
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Alopecia areata pathophys & tx |
Immune mediated loss of hair - lymphs Usually regrows spontaneously w/in 1 yr, can give systemic, topical steroids or minoxidil / immune modulation |
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Facial red macules & papules, spreading inferiorly w/in 2-3 days & fading w/in 4-6 days w/ subsequent desquamation + white papules on red base over buccal mucosa |
Measles (rubeola) - Koplik spots pathognomonic |
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Blanchable macules on hands / feet (incl palms & soles) spreading to trunk w/in 6-18 hrs. Becomes non-blanchable w/in 2-4 days |
RMSF |
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Red papules that coalesce on face, reticulate rash on butt & upper arms (can include palms/soles), may have red spots on mucous membranes |
Erythema infectious (Parvovirus, 5th dz) |
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Red macules over arms & legs --> hemorrhagic, painful pustules w/in 2-3 days |
Gonococcemia |
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Ham-colored papules over trunk, palms, soles, genitals |
2' syphilis |
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red macules/plaques on hands/feet --> trunk / extremities w/in 2 days + fever |
Kawasaki dz |
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Ash leaf |
Tuberous sclerosis |
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raised patches on lower back w/ orange-peel texture |
Shagreen patch - Tuberous sclerosis |
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Red vascular nodules on face - look like aggravated acne |
Adenoma sebaceum - Tuberous sclerosis |
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Periungal fibromas |
Tuberous sclerosis |
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Cafe-au-lait spots |
NF 1 - cafe au lait, macrocephaly, MR, feeding problems
Note: NF2 = bilateral acoustic neuromas, cataracts, not assc w/ cafe-au-lait spots
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Tender, vioaceous SQ nodules on palms/soles |
Osler's nodes - Bacterial endocarditis |
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Hemorrhagic nontender macules on fingers/toes |
Janeway lesions - Bacterial endocarditis |
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Subungual splinter hemorrhages |
Bacterial endocarditis |
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Hyperpigmented macules on nose, mouth, hands, feet |
Lentigines - Peutz-Jeghers syn |
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Well-demarcated, indurated, elevated advancing border, local pain Fever, malaise, shivering
Bug & drug? |
Erysipelas GAS Penicillin, cephalosporin, macrolide, vanc |
