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17 Cards in this Set
- Front
- Back
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MOA OF ASPIRIN |
blocks thromboxane synthesis from arachidonic acid by irreversible acetylation and inhibition of cyclooxygenase |
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USES OF ASA |
anti thrombotic anti inflammatory antipyretic analgesic txt of MI |
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moa of ticlopidine |
inhibit ADP Pathway involved in the binding of platelets to fibrinogen to fibrin |
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MOA of dipyridamole |
inhibits thromboxane synthesis by increasing IC levels of CAMP and inhibiting cyclic nucleotide phosphodiesterase |
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moa of abciximab, eptifibatide and tirofiban |
block platelet glycoprotein receptors |
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what is alteplase |
a tissue type plasminogen activator serine protease derived substance from cultured human melanoma cells |
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use of alteplase |
txt of MI txt of severe pulmonary embolism txt of ischemic stroke |
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what is streptokinase |
extracellular protein purified from group c beta hemolytic streptococci |
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use of streptokinase |
txt of pulmonary embolism txt of DVT txt of acute MI |
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what is anistreplase |
anisoylated plasminogen streptokinase an activator complex (purified human plasminogen + bacterial streptokinase) |
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what is urokinase |
an enzyme that degrades fibrin and fibrinogen obtained from the cultures of human fetal renal cells |
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use of urokinase |
txt of severe pulmonary emboli txt of DVT |
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difference of heparin and coumarin derivatives |
def: h: endogenous substance from liver c: tonka bean roa h: parenterally c: orally antidote h: protamine sulfate c: vitamin k |
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what is aminocaproic acid |
aka tranexamic acid inhibit plasminogen activation |
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what is protamine sulfate |
derived from fish sperm/ testis |
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what is vitamin k |
promotes normal blood clot formation |
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what is aprotinin |
serine protease inhibitor |
