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24 Cards in this Set

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Dysphagia (difficulty swallowing)
Caused by:
Narrowing of esophagus
Decreased salivary secretion
Nerve damage
Scleroderma
Stroke
Manifestations:
Odynophagia: pain associated with swallowing
Hernia (protrusion of tissue through muscular wall)
Caused by: weakening of the wall allowing tissue protrusion

Sliding Hiatal Hernia: protrusion of stomach above diaphragm

Paraesophageal Hiatal Hernia: separate portion of stomach enters thorax
Manifestations:
Pain
Gastroesophageal Reflux Disease (GERD - backward movement of gastric contents back into esophagus)
Caused by:
Weak or incompetent lower sphincter
Delayed gastric emptying
Mucosal injury
Manifestations:
Heartburn
Chronic cough
Gastroesphageal Asthma
Hoarseness
May cause Barrett's Esophagus (precancerous state)
Esophageal Cancer (carcinoma of the esophagus)
Caused by:
Squamous: alcohol and tobacco use

Adenocarcinoma: Barrett esophagus
Manifestations:
Dysphagia
Odynophagia
Weight loss
Fatigue
Metastasis often has occured at time of Dx
Mallory-Weiss Syndrome (longitudinal esophageal tears)
Caused by:
Chronic Alcoholism, Bulimia, Violent/Powerful bouts of gagging (retching) & vomiting lead to very dilated esophageal veins very susceptible to laceration
Manifestations:
Bleeding (can be severe and life threatening)
Inflammatory Ulcer
Mediastinitis
Acute Gastritis (inflammation of gastric mucosa)
Caused by:
Irritants (alcohol, NSAIDs, bacterial toxins)
Manifestations:
Heartburn
Gastric Distress
Peptic Ulcer (ulcer affecting one or all layers of the stomach or duodenum)
Caused by:
Bacteria (H. pylori)
NSAIDs
Aspirin
Manifestations:
Epigastric Pain

Complications:
hemorrhage, perforation, penetration, hematemesis, & melena
Gastric Carcinoma (stomach cancer)
Caused by:
Genetic
Bacteria (H. pylori)
Nitrosamines
Autoimmune gastritis
Manifestations (Asymptomatic until late):
Epigastric pain
Vomiting
Anorexia
Cachexia
Irritable Bowel Syndrome (IBS - unexplained chronic and recurrent intestinal symptoms)
Caused by:
CNS deregulation of peristalsis
Psychological or physiological stress
More common in women
Manifestations:
Abdominal pain
Flatulence
Bloating
Nausea
Anxiety/Depression
Constipation/Diarrhea
Ulcerative Colitis (nonspecific inflammatory condition of the colon)
Caused by:
Genetic
Autoimmune (microbial trigger)
Manifestations:
Fecal urgency
Diarrhea
Weight loss
Anemia
Arthritis
Skin lesions
Thrombosis

Complications:
Toxic Megacolon, Colon Cancer
Crohn's Disease (recurrent granulomatous inflammation affecting the GI tract)
Caused by:
Genetic
Autoimmune (microbial trigger)
Manifestations:
Fecal urgency
Diarrhea
Weight loss
Anemia
Arthritis
Skin lesions
Thrombosis
Fistulas (abnormal passageway between two organs or vessels)
Skip Lesions (cobblestone)
Infectious Enterocolitis (inflammation of the small intestine and colon caused by a microbial agent)
Caused by:
Viral (rotavirus)
Bacterial (C. difficile-generally following broad spectrum antibiotic therapy or E. coli)
Manifestations:
Viral-Fever, Vomiting, Diarrhea

Bacterial, C. diff: Diarrhea, Cramping, Dehydration, Fever

Bacterial, E. coli: Hemorrhagic Colitis, Diarrhea, Renal Failure, TTP


Diverticulitis (diverticulosis-mucosal layer of colon herniates through muscularis layer, "outpouching" then becomes inflamed)
Caused by:
Low exercise
Low fiber consumption
Neglecting defecation urge
Manifestations:
Lower left quadrant pain
Nausea
Vomiting
Fever

Complications: fistulas(abnormal passage between 2 organs or vessels), hemorrhage, septic peritonitis & obstruction
Appendicitis (appendix becomes inflamed, swollen, and gangrenous)
Caused by:
Obstruction (by hard stool)
Twisting
Manifestations:
Epigastric/Preumbilical pain until rupture-short relief until intense pain from septic peritonitis
Board-like abdominal rigidity
*Rebound tenderness (unique, pain occurs when pressure is release not inflicted)
Inflammatory Diarrhea (Small Volume)
Caused by:
Crohn's Disease, Ulcerative Colitis (IBD)
Inflammatory Manifestations:
Fever
Bloody diarrhea
Non-Inflammatory Diarrhea (Large Volume)
Caused by:
Osmotic - water is pulled into bowel due to hyperosmotic contents
(lactase deficiency-lactose intolerant patients, sorbitol-sugar in diabetic candies)

Secretory - toxins from bacterial or viral infections (C. diff., E. coli), food poisoning
Non-Inflammatory Manifestations:
Excessive watery and non-bloody stools
Periumbilical cramps
Nausea
Vomiting
Bloating
Constipation (Infrequent or difficult passage of stools)
Caused by:
Decreased intestinal motility
Drugs
Inadequate fiber and fluid intake
Weakened abdominal muscles
Pregnancy
Manifestations:
Abdominal Pain
Bloating
Fecal Impaction (Retention of hardened stools in the rectum and colon)
Caused by:
Drugs (antacids, bulk laxatives)
Age (elderly)
Low residue diet
Prolonged bed rest
Manifestations:
Severe constipation
Watery diarrhea
Fecal soiling
Fecal incontinence
Peritonitis (Inflammation of membrane lining the abdominal cavity)
Caused by:
Bacteria
Chemical irritation
Rupture Appendix (acute)
Pelvic Inflammatory Disease (chronic)
Manifestations:
Nausea
Vomiting
Abdominal tenderness (stiff)
Fever
Shock
Acute vs. Chronic Diarrhea
Acute Diarrhea (excessively frequent passage of stools for less than 2 weeks)
Chronic Diarrhea (excessively frequent passage of stools for 3 to 4 weeks)
Steatorrhea (Inability to absorb fats from diet)
Caused by:
Inadequate pancreatic lipase, bile salts, or lymphatic channels
Manifestations:
Yellow-gray stools
Weight loss
Fat soluble vitamin deficiency

Celiac Disease (Immune disorder triggered by ingestion of gluten)
Caused by:
Genetic
Higher incidence in diabetics and females
Manifestations:
Diarrhea
Constipation
Bloating
Flatus
Chronic dermatitis
Adenomatous Polyps (Benign neoplasms of intestinal epithelium)
Caused by:
Advancing Age
Manifestations:
Asymptomatic

Types:
Pedunculated: stalk
Tubular: smooth, tubule, gland like
Villous/Sessile: raised, cauliflower surface
Tubulovillous: both raised & tubule
Colorectal Cancer (Cancer of the colon and rectum, common, high mortality rate)
Caused by:
Adenomatous polyps
Chronic GI inflammation
Genetic
Diets high in fat and sugar
Low fiber intake

*aspirin may decrease incidence
Manifestations:
Blood in stool
Bowel habit change
Pain (late manifestation)