Pathology_3 09: Liver

Front 1

5 patterns of liver injury

Back 1

necrosis
degeneration
inflammation
regeneration
fibrosis

Front 2

4 degrees of liver necrosis

Back 2

focal
zonal
submassive
massive

Front 3

___ necrosis is typical of viral Hep

Back 3

focal

Front 4

zonal aka ___ (2) necrosis is typical of ___ (2).

Back 4

centrilobular
periportal
drug injury
ischemia

Front 5

3 non-Hep viruses which cause hep

Back 5

HSV
EBV
CMV

Front 6

HGV causes ___ liver injury

Back 6

no

Front 7

4 hep syndromes

Back 7

carrier state
acute viral hep
chronic hep
fulminant hep

Front 8

T/F: you can dx viral hep based on biopsy

Back 8

false: need serology

Front 9

Hep viruses which cause acute hep

Back 9

all 5

Front 10

Hep viruses which cause chronic hep

Back 10

HBV
HCV
HDV

Front 11

councilman bodies indicate ___. they are made of ___.

Back 11

necrosis
apoptotic hepatocytes

Front 12

reactive changes in acute hep

Back 12

Kuppfer cell hypertrophy and hyperplasia
portal inflammation

Front 13

chronic hep is defined by ___ or ___ evidence of hep for > ___ months

Back 13

symptomatic
serological
6

Front 14

3 drugs which cause chronic hep

Back 14

INH
alpha methyl dopa
MTX

Front 15

hep staging is based on ___. hep grading is based on ___ (2).

Back 15

fibrosis
necrosis
inflammation

Front 16

morphologic change in HBV

Back 16

ground-glass hepatocytes

Front 17

reactive changes in acute hep

Back 17

Kuppfer cell hypertrophy and hyperplasia
portal inflammation

Front 18

chronic hep is defined by ___ or ___ evidence of hep for > ___ months

Back 18

symptomatic
serological
6

Front 19

3 drugs which cause chronic hep

Back 19

INH
alpha methyl dopa
MTX

Front 20

hep staging is based on ___. hep grading is based on ___ (2).

Back 20

fibrosis
necrosis
inflammation

Front 21

morphologic change in HBV

Back 21

ground-glass hepatocytes

Front 22

in autoimmune hep ___ cells predominate in ___.

Back 22

plasma
inflammatory infiltrate

Front 23

80% of autoimmune hep pts are ___

Back 23

women

Front 24

80% of autoimmune hep has ___

Back 24

auto-Abs

Front 25

3 Abs in autoimmune hep

Back 25

ANA
SMA
liver kidney microsomal (LKM)

Front 26

fulminant hep is caused most frequently by ___

Back 26

drugs/toxins

Front 27

5 drugs/toxins which cause fulminant hep

Back 27

acetaminophen
INH
methyl dopa
halothane
amanita toxin

Front 28

2 drugs which cause DILI

Back 28

chlorpromazine
halothane

Front 29

T/F: DILI always happens immediately

Back 29

false

Front 30

T/F: DILI resembles viral hep

Back 30

true