Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
34 Cards in this Set
- Front
- Back
Prion disease
|
??
|
|
Prion disease
-spongiform with plaques |
Dx?
|
|
Prion disease
-plaques are shown...cool |
Dx?
|
|
Alzheimers
-neurofibrillary tangles -senile plaques |
Dx?
|
|
Alzheimers
-senile plaques |
Dx?
|
|
Alzheimers
-Senile plaques = Beta-amyloid -neurofibrillary tangles = tau protein |
Whats the diagnosis bitches?
|
|
Alzheimers
-neurofibrillary tangles |
Dx?
|
|
Alzheimers
-nope, not Pick's disease u silly fuck |
Dx?
|
|
Pick's Disease
|
Dx?
|
|
Pick's Disease
-Pick bodies = tau |
Dx?
|
|
-Lewy bodies = contain alpha-synuclein protein
-Parkinson's |
What is this called?
What disease? |
|
Parkinson's with Lewy body
|
Dx?
|
|
This is a cause of Parkinsonism
|
Multiple System Atrophy
-honestly, i don't know what the fuck is going on in this picture |
|
Multiple System Atrophy
|
This causes Parkinsonism
|
|
Progressive Supranuclear Palsy
|
This is when many nuclei are involved & Parkinsonism also develops
|
|
Progressive Supranuclear Palsy
-if this is on our test I will probably pull a Cho |
This is a cause of Parkinsonism
|
|
Corticobasal Degeneration
|
-Occurs in the motor, premotor cortex
-Ballooned neurons -Tau-positive inclusions in Astrocytes, Oligos, neurons -causes Parkinsonism |
|
ALS
|
This disease affects Anterior horn cells in Spinal Cord & Motor nuclei in Brain stem
|
|
ALS = degeneration of axons/myelin in Lateral & Anterior Corticospinal tracts
*this is also a xeroxed copy of my mom's ass during a drunken work christmas party |
Dx?
|
|
ALS
|
Dx?
|
|
Huntington Disease = chorea + dementia
|
Dx?
|
|
Huntington Disease
-atrophy of Caudate Nucleus, Putamen, Frontal Cortex |
Pathology on right?
|
|
Friedrich's Ataxia
-Posterior = diminished joint sensation -Lateral = spasticity Hypertrophic Cardiomyopathy |
Loss of posterior & lateral columns of Spinal Cord?
Most frequent cause of death in this disorder? |
|
Acute Hemorrhagic Leukoencephalitis
Hyperacute, follows respiratory infection |
What is this?
Describe the clinical scenario |
|
Acute Hemorrhagic Leukoencephalitis
|
WHat is seen here?
|
|
Progressive Multifocal Leukoencephalopathy = JC virus...aka the Jesus Christ virus
|
What is seen here?
|
|
Progressive Multifocal Leukoencephalopathy
-occurs in IC'ed patients |
Dx?
|
|
Central Pontine Myelinosis
Person comes in who is Hyponatremic --> rapid correction causes this |
Dx?
Clinical scenario? |
|
Adrenoleukodystrophy
Unable to Beta-oxidize "very long chain fatty acids" = LCFA's in peroxisomes |
What is seen here?
Mechanism? |
|
Adrenoleukodystrophy
-LCFA in peroxisomes -parieto-occipital myelin loss |
Dx?
|
|
Metachromatic Leukodystrophy
Arylsulfatase A deficiency = Autosomal Recessive -Sulfatides accumulate -Children = motor symptoms -Adults = psychiatric symptoms |
Dx?
Mechanism? |
|
Multiple Sclerosis
|
Patient has Oligoclonal bands in CSF...diagnosis?
|
|
Multiple Sclerosis
|
Dx?
|
|
Multiple Sclersosis - Balo's Concentric type
|
Dx?
|