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142 Cards in this Set

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Banded (left) and segmented (right) neutrophil

Lymphocyte (left)

Eosinophil (right)

Basophil (center)

Monocyte

Reticulocytes

Marrow smear from a patient withhemolytic anemia. Increased numbers of maturing erythroidprogenitors (normoblasts)

Spherocyte

Bite cell (from G6PD deficiency)

Sickle cells (showing anisocytosis and poikilocytosis)

Autoinfarcted spleen remnant (from SCD)

Crew cut appearance of skull (from beta thalassemia)

Reticulocyte fragments (schistocytes) from microangiopathic anemia

Hypersegmented neutrophil seen in megaloblastic anemia

Iron deficiency anemia (hypochromic and small RBC's)

Hypocellular bone marrow (from aplastic anemia)

Thrombocytopenia (from aplastic anemia)

Intravascular thrombi (from thrombotic microangiopathies)

Fragmented RBC's (schistocytes) from hemolytic uremic syndrome

Bone marrow showing adipocytes (black arrow), bony trabeculae (red arrow), hematopoietic marrow elements (green arrow)

Hyperplastic bone marrow (fat cells disappear in this condition)

Hypocellular bone marrow (incr fat is seen)

Reactive changes in neutrophils in agranulocytosis; you can see the Dohle bodies (arrow) which represent dilated ER

Reactive follicle (caused by follicular hyperplasia seen in chronic nonspecific lymphadenitis) showing dark staining mantle zone (green arrow), light zone (blue arrow), and dark zone (orange arrow)

Reactive follicle (caused by follicular hyperplasia seen in chronic nonspecific lymphadenitis) showing mitotic figures & numerous macros (green arrow) containing phagocytosed apoptotic cells (tingible bodies).

ALL (arrow points to lymphoblast which have little cytoplasm, lack peroxidase, small nucleoli, condensed nuclear c'tin)

AML (arrow points to myeloblast which have more voluminous cytoplasm, prominent nucleoli, azurophilic cytoplasmic granules)

SLL/CLL lymph node; arrow shows diffuseeffacement of nodal architecture

SLL/CLL lymph node; green arrow shows pro lymphocytes (larger cells with centrally placed nucleoli) and yellow arrow shows small round lymphocytes

SLL/CLL; green arrow shows smudge cells and red arrow shows spherocytes

Follicular lymphoma (arrow shows nodules)

Arrow points to an absent BCL2, indicating it is not a follicular lymphoma

Arrow points to BCL2, indicating it is a follicular lymphoma

Follicular lymphoma; green arrow points to centrocytes, red arrow points to centroblasts

DLBCL (arrow shows rapidly enlarging, symptomaticmass at a nodal or extra nodal site)

DLBCL (arrow shows large and prominent nuclei)

Burkitt lymphoma (arrow shows macros with clear space around them, representing 'starry-sky' appearance)

Burkitt lymphoma (high mitotic index, multiple small nucleoli)

Skull in multiple myeloma; arrow shows punched out bone lesion

Bone marrow in multiple myeloma; plasma cells fill BM with arrow showing multiple nuclei

Bone marrow in multiple myeloma; plasma cells fill BM with arrow showing cytoplasmic droplets containing Ig

Mantle cell lymphoma; image shows neoplastic lymphoid cells surrounding a small, atrophic germinal center (a mantle zone pattern of growth)

Hairy cell leukemia; arrow shows fine hair-like cytoplasmic projections and extensions

Hairy cell leukemia; arrow shows stained smears, roundor folded nuclei & agranularcytoplasm

Hodgkin lymphoma; shows Reed Sternberg cells

Hodgkin lymphoma; arrow shows mononuclear variant

Nodular sclerosis (HL); arrow shows lacunar variant

Hodgkin lymphoma; arrow shows lymphohistocytic variant

Nodular sclerosis (HL); arrow shows collagen band dividing the lymphoid tissue into nodules

Mixed cellularity (HL); arrow shows diagnostic RS cells

Lymphocyte predominant (HL); arrows show lymphocytic and histocytic variants

AML w/ t(15:17); arrow shows aurer rods

AML w/ monocytic differentiation; arrow shows monoblast

Myelodysplastic syndrome; arrow shows neutro with 2 nuclear lobes

CML; green arrow shows mature neutrophil and red arrow shows immature neutrophil

Polycythemia vera spent phase; massive splenomegaly due to EMH in the setting of advanced marrow myelofibrosis

Essential thrombocytosis; peripheral blood smear shows markedthrombocytosis, including giant platelets

Primary myelofibrosis; green arrow shows nucleated erythroid precursor and orange arrow shows tear drop shaped RBC's (dacryocytes)

Langerhans histiocytosis; arrow shows birbeck granules

Cd-1a positive and S-100 positive

Acute mastitis

Acute mastitis; black dots represent neutrophils

Granulomatous mastitis

Granulomatous mastitis

Periductal mastitis (Zuska disease)

Mammary duct ectasia; arrow shows dilated ducts filled with lipid-laden macros

Mammary duct ectasia (white discharge from nipple)

Fat necrosis; picture shows speculated lesion on mammogram

Fat necrosis; picture shows liquefactive necrosis and foamy lipid filled macros

Non proliferative breast cyst (fibrocystic); arrow shows apocrine metaplasia

Non proliferative breast cyst (fibrocystic); picture shows calcifications

Epithelial hyperplasia; arrow shows irregular slit-like lumen

Sclerosing adenosis

Complex sclerosing lesion; picture shows central scar

Complex sclerosing lesion; arrow shows solid irregular mass

-Complex sclerosing lesion;


-Top arrow shows central nidus of small tubules entrapped in dense fibrous stroma


-Bottom arrow shows cysts/hyperplasia

Papilloma; blood stained discharge

Papilloma

Atypical ductal hyperplasia

Atypical lobular hyperplasia

Normal/non proliferative breast

Proliferative disease of breast

Atypical hyperplasia of breast

Carcinoma in situ of breast

Invasive carcinoma of breast

Fibroma; yellow arrow showing the fibrous tissue and green arrow showing squamous mucosa

Fibroma; arrow shows ulcerated nodular fibroma

Aphthous ulcer (canker sores); top arrow shows hyperemic ulcer, bottom arrow shows narrow zone of erythema

Glossitis

Oral herpes; arrow shows abrupt onset of vesicles and ulcers

Oral herpes; arrow shows abrupt onset of vesicles and ulcers

Oral herpes; arrow shows multinucleated cells from the Tzanck test

Oral herpes; arrow shows intranuclear inclusions cells from the Tzanck test

Oral candidiasis; arrow shows pseudomembrane

Oral candidiasis; green arrow shows oval yeast like budding cells and yellow arrow shows pseudohyphae

Hairy leukoplakia; white confluent patches on the lateral border of tongue

Hairy leukoplakia; arrow shows ballooning of squamous cells in upper epithelium

Leukoplakia; arrow shows homogenous area (uniformly white)

Leukoplakia; arrow shows speckled leukoplakia (white and red) and also known as leukoerythroplakia

Leukoplakia; arrow shows verrucousleukoplakia – corrugated/nodular

Leukoplakia; arrow shows hyperkeratosis and thickened, acanthoticepithelium

Erythroplakia; shows red velvet slightly depressed plaque

Oral cancer; picture shows proliferative mass

Oral cancer; arrow shows keratin pearls

Oral cancer; picture shows ulcerated mass

Nasopharyngeal undifferentiated carcinoma; non neoplastic lymphoid cells with vesicular nuclei and prominent nucleoli in syncitial

Larynx; left arrow shows keratotic, hyper plastic epithelium and right arrow shows loose myxoid CT core

Larynx; arrow points to vocal cord nodules

Carcinoma larynx

Carcinoma larynx

Branchial cyst

Thyroglossal cyst

Paraganglioma (carotid body tumor); picture shows zellballen

Pleomorphic adenoma; picture shows myxoidareas and chondroid areas

Pleomorphic adenoma; top arrow shows epithelial/myoepithelial cells and bottom arrow shows mesenchyme like stroma

Warthin's tumor; green arrow shows double cell layer and blue arrow shows stroma (mature lymphoid follicles with germinal center)

Mucoepidermoidcarcinoma; blue arrow shows mucuscells secreting mucus and red arrow shows squamous cells

Mucoepidermoid carcinoma; picture shows mucicarminestains the mucin reddish pink

Adenoid cystic carcinoma; arrow shows small cells – tubular, solid &cribriform pattern

Adenoid cystic carcinoma; red arrow shows the nerve which hasbeen invaded by malignant cells shown by green arrow

Normal muscle with checker board distribution of type 1 (light) and type 2(dark) fibers

Type grouping of muscle fibers in re-innervation and regeneration

Clustered atrophic muscle fibers in denervation (arrow)

Peripheral neuropathy in adult onset of DM; arrow head shows loss of myelinated fiber, arrow shows thickeningof endoneurialvessel wall



Propoptosis

Propoptosis

Chalazion; picture shows meibomian gland

Stye; picture shows infected eyelid

Pterygium (conjuctiva infection); fibrovasc CT invading cornea. Resembles a fan shape

Pinguecla (conjuctiva infection); picture shows small yellow discoloration. No cornea invasion

Keratinous; picture shows thinningofthe corneaw/ breaks in Bowman

Keratomalacia; picture shows xerosis and bitot spot

Lens cataract; picture shows glare

Iris melanoma; picture shows pigmented mass

Epithelial melanoma cells; largecells, vesicular nucl; prominent nucleolus, melanin pigment+

Hypertensive retinopathy; picture shows vein compressed where the sclerotic arteriole crosses over it

Non-proliferativediabetic retinopathy; b/w the arrows shows tangleof abnormal vessels lying just beneath the internal limiting membrane of theretina

Proliferative diabetic retinopathy; picture is anex of intraretinalangiogenesis known asintraretinalmicroangiopathy(IRMA)

Retinoblastoma

Retinoblastoma; red eye reflex seen in normal retina, white means there is something wrong

Retinoblastoma; red arrow shows Flexner-Wintersteinerrosettes, black arrow shows smallblue cells-round with hyperchromaticnuclei, scanty cytoplasm

Retinoblastoma; shows necrosis and dystrophic calcification

Flexner-Wintersteiner rosette; seen in retinoblastoma. Picture shows central lumen around which the cellsaggregate (Gives a flower appearance aka fleurretes)