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5 Cards in this Set
- Front
- Back
Substances produced by endothelium that affects hemostasis and thrombosis
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- antithrombotic factors (heparin-like substance)
- tissue plasminogen - vasoactive factors (prostacyclin) - platelet aggregation inhibitor - vasodilator (endothelin) - factors that promote thrombosis (vWF, PAI-1) |
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platelet receptor for collagen
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glycoprotein Ia, IIa
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platelet receptor for vWF
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glycoprotein Ib
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platelet receptor for fibrinogen
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glycoprotein IIb, IIIa
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how does aspirin affect platelet fnxn
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aspirin inhibits platelet function
- inhibits cyclooxygenase so thromboxane A2 is not formed - decreases platelet aggregation |